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APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans

APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_307677

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Atherosclerotic cardiovascular disease causes heart attacks and strokes, which are the leading causes of mortality worldwide
1
. The formation of atherosclerotic plaques is initiated when low-density lipoproteins bind to heparan-sulfate proteoglycans (HSPGs)
2
and become trapped in the subendothelial space of large and medium size arter...

Alternative Titles

Full title

APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_gup_ub_gu_se_307677

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_307677

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-021-03818-3

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