Safety and efficacy of factorXIa inhibition with milvexian for secondary stroke prevention (AXIOMATI...
Safety and efficacy of factorXIa inhibition with milvexian for secondary stroke prevention (AXIOMATIC-SSP) : a phase 2, international, randomised, double-blind, placebo-controlled, dose-finding trial
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Author / Creator
Sharma, Mukul , Molina, Carlos A. , Toyoda, Kazunori , Bereczki, Daniel , Bangdiwala, Shrikant , Kasner, Scott E. , Lutsep, Helmi L. , Tsivgoulis, Georgios , Ntaios, George , Czlonkowska, Anna , Shuaib, Ashfaq , Amarenco, Pierre , Endres, Matthias , Yoon, Byung-Woo , Tanne, David , Toni, Danilo , Yperzeele, Laetitia , von Weitzel-Mudersbach, Paul , Silva, Gisele Sampaio , Avezum, Alvaro , Dawson, Jesse , Strbian, Daniel , Tatlisumak, Turgut , Eckstein, Jens , Ameriso, Sebastian F. , Weber, Joerg R. , Sandset, Else Charlotte , Pogosova, Nana Goar , Lavados, Pablo M. , Arauz, Antonio , Gailani, David , Diener, Hans-Christoph , Bernstein, Richard A. , Cordonnier, Charlotte , Kahl, Anja , Abelian, Grigor , Donovan, Mark , Pachai, Chahin , Li, Danshi and Hankey, Graeme J.
Journal title
Language
English
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Scope and Contents
Contents
Background People with factor XI deficiency have lower rates of is chaemic stroke than the general population and infrequent spontaneous bleeding, suggesting that factor XI has a more important role in thrombosis than in haemostasis. Milvexian, an oral small-molecule inhibitor of activated factor XI, added to standard antiplatelet therapy, might re...
Alternative Titles
Full title
Safety and efficacy of factorXIa inhibition with milvexian for secondary stroke prevention (AXIOMATIC-SSP) : a phase 2, international, randomised, double-blind, placebo-controlled, dose-finding trial
Authors, Artists and Contributors
Author / Creator
Molina, Carlos A.
Toyoda, Kazunori
Bereczki, Daniel
Bangdiwala, Shrikant
Kasner, Scott E.
Lutsep, Helmi L.
Tsivgoulis, Georgios
Ntaios, George
Czlonkowska, Anna
Shuaib, Ashfaq
Amarenco, Pierre
Endres, Matthias
Yoon, Byung-Woo
Tanne, David
Toni, Danilo
Yperzeele, Laetitia
von Weitzel-Mudersbach, Paul
Silva, Gisele Sampaio
Avezum, Alvaro
Dawson, Jesse
Strbian, Daniel
Tatlisumak, Turgut
Eckstein, Jens
Ameriso, Sebastian F.
Weber, Joerg R.
Sandset, Else Charlotte
Pogosova, Nana Goar
Lavados, Pablo M.
Arauz, Antonio
Gailani, David
Diener, Hans-Christoph
Bernstein, Richard A.
Cordonnier, Charlotte
Kahl, Anja
Abelian, Grigor
Donovan, Mark
Pachai, Chahin
Li, Danshi
Hankey, Graeme J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_gup_ub_gu_se_334571
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_334571
Other Identifiers
ISSN
1474-4422,1474-4465
DOI
10.1016/S1474-4422(23)00403-9
