Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multi...
Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis
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HNCIG-EPIC group , Mehanna, Hisham, Prof , Taberna, Miren, PhD , von Buchwald, Christian, Prof , Tous, Sara, BSc , Brooks, Jill, PhD , Mena, Marisa, PhD , Morey, Francisca, BSc , Grønhøj, Christian, Prof , Rasmussen, Jacob Høygaard, PhD , Garset-Zamani, Martin, MD , Bruni, Laia, PhD , Batis, Nikolaos, PhD , Brakenhoff, Ruud H, Prof , Leemans, C René, Prof , Baatenburg de Jong, Robert J, Prof , Klussmann, Jens Peter, Prof , Wuerdemann, Nora, MD , Wagner, Steffen, Dr. rer. nat , Dalianis, Tina, Prof , Marklund, Linda, Prof , Mirghani, Haïtham, Prof , Schache, Andrew, PhD , James, Jaqueline A, Prof , Huang, Shao Hui, Prof , O'Sullivan, Brian, Prof , Nankivell, Paul, PhD , Broglie, Martina A, MD , Hoffmann, Markus, Prof , Quabius, Elgar Susanne, MD and Alemany, Laia, PhD
Publisher
England: Elsevier Ltd
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English
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Publisher
England: Elsevier Ltd
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Contents
SummaryBackgroundp16 INK4a (p16) immunohistochemistry is the most widely used biomarker assay for inferring HPV causation in oropharyngeal cancer in clinical and trial settings. However, discordance exists between p16 and HPV DNA or RNA status in some patients with oropharyngeal cancer. We aimed to clearly quantify the extent of discordance, and it...
Alternative Titles
Full title
Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis
Authors, Artists and Contributors
Author / Creator
Mehanna, Hisham, Prof
Taberna, Miren, PhD
von Buchwald, Christian, Prof
Tous, Sara, BSc
Brooks, Jill, PhD
Mena, Marisa, PhD
Morey, Francisca, BSc
Grønhøj, Christian, Prof
Rasmussen, Jacob Høygaard, PhD
Garset-Zamani, Martin, MD
Bruni, Laia, PhD
Batis, Nikolaos, PhD
Brakenhoff, Ruud H, Prof
Leemans, C René, Prof
Baatenburg de Jong, Robert J, Prof
Klussmann, Jens Peter, Prof
Wuerdemann, Nora, MD
Wagner, Steffen, Dr. rer. nat
Dalianis, Tina, Prof
Marklund, Linda, Prof
Mirghani, Haïtham, Prof
Schache, Andrew, PhD
James, Jaqueline A, Prof
Huang, Shao Hui, Prof
O'Sullivan, Brian, Prof
Nankivell, Paul, PhD
Broglie, Martina A, MD
Hoffmann, Markus, Prof
Quabius, Elgar Susanne, MD
Alemany, Laia, PhD
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Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_447707
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_447707
Other Identifiers
ISSN
1470-2045,1474-5488
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(23)00013-X