FinnGen provides genetic insights from a well-phenotyped isolated population
FinnGen provides genetic insights from a well-phenotyped isolated population
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Author / Creator
FinnGen , Kurki, Mitja I. , Karjalainen, Juha , Palta, Priit , Sipilä, Timo P. , Donner, Kati M. , Reeve, Mary P. , Laivuori, Hannele , Kaunisto, Mari A. , Loukola, Anu , Lahtela, Elisa , Mattsson, Hannele , Laiho, Päivi , Della Briotta Parolo, Pietro , Lehisto, Arto A. , Kanai, Masahiro , Mars, Nina , Heyne, Henrike O. , Veerapen, Kumar , Rüeger, Sina , Lemmelä, Susanna , Zhou, Wei , Ruotsalainen, Sanni , Pärn, Kalle , Hiekkalinna, Tero , Koskelainen, Sami , Llorens, Vincent , Gracia-Tabuenca, Javier , Siirtola, Harri , Reis, Kadri , Elnahas, Abdelrahman G. , Aalto-Setälä, Katriina , Biswas, Shameek , Dada, Oluwaseun A. , Ding, Zhihao , Ehm, Margaret G. , Eklund, Kari , Färkkilä, Martti , Finucane, Hilary , Ganna, Andrea , Ghazal, Awaisa , Hakanen, Antti , Hu, Xinli , Hunkapiller, Julie , Jacob, Howard , Jensen, Jan-Nygaard , Joensuu, Heikki , John, Sally , Junttila, Juhani , Kähönen, Mika , Kallio, Lila , Kaprio, Jaakko , Kettunen, Johannes , Kilpeläinen, Elina , Kosma, Veli-Matti , Kuopio, Teijo , Laisk, Triin , Laukkanen, Jari , Liu, Aoxing , Mägi, Reedik , Mäkitie, Antti , Malarstig, Anders , Maranville, Joseph , Niemi, Mari E. K. , Niemi, Marianna , Obeidat, Ma´en , Okafo, George , Palomäki, Antti , Palotie, Tuula , Pitkäranta, Anne , Pulford, David , Raghavan, Neha , Rahimov, Fedik , Riley-Gillis, Bridget , Rodosthenous, Rodosthenis , Salminen, Eveliina , Salomaa, Veikko , Schleutker, Johanna , Serpi, Raisa , Shen, Huei-yi , Siegel, Richard , Sul, Jae Hoon , Tachmazidou, Ioanna , Tienari, Pentti , Tukiainen, Taru , Vaura, Felix , Virolainen, Petri , Waring, Jeffrey , Waterworth, Dawn , Yang, Robert , Nelis, Mari , Metspalu, Andres , Milani, Lili , Fox, Caroline , Havulinna, Aki S. , Perola, Markus , Jalanko, Anu , Plenge, Robert , Runz, Heiko , Daly, Mark J. and Palotie, Aarno
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor allele frequency < 5%). These variants survived the founding bottleneck rather than being distributed over a large number of ultrarare variants. Although this effect is we...
Alternative Titles
Full title
FinnGen provides genetic insights from a well-phenotyped isolated population
Authors, Artists and Contributors
Author / Creator
Kurki, Mitja I.
Karjalainen, Juha
Palta, Priit
Sipilä, Timo P.
Donner, Kati M.
Reeve, Mary P.
Laivuori, Hannele
Kaunisto, Mari A.
Loukola, Anu
Lahtela, Elisa
Mattsson, Hannele
Laiho, Päivi
Della Briotta Parolo, Pietro
Lehisto, Arto A.
Kanai, Masahiro
Mars, Nina
Heyne, Henrike O.
Veerapen, Kumar
Rüeger, Sina
Lemmelä, Susanna
Zhou, Wei
Ruotsalainen, Sanni
Pärn, Kalle
Hiekkalinna, Tero
Koskelainen, Sami
Llorens, Vincent
Gracia-Tabuenca, Javier
Siirtola, Harri
Reis, Kadri
Elnahas, Abdelrahman G.
Aalto-Setälä, Katriina
Biswas, Shameek
Dada, Oluwaseun A.
Ding, Zhihao
Ehm, Margaret G.
Eklund, Kari
Färkkilä, Martti
Finucane, Hilary
Ganna, Andrea
Ghazal, Awaisa
Hakanen, Antti
Hu, Xinli
Hunkapiller, Julie
Jacob, Howard
Jensen, Jan-Nygaard
Joensuu, Heikki
John, Sally
Junttila, Juhani
Kähönen, Mika
Kallio, Lila
Kaprio, Jaakko
Kettunen, Johannes
Kilpeläinen, Elina
Kosma, Veli-Matti
Kuopio, Teijo
Laisk, Triin
Laukkanen, Jari
Liu, Aoxing
Mägi, Reedik
Mäkitie, Antti
Malarstig, Anders
Maranville, Joseph
Niemi, Mari E. K.
Niemi, Marianna
Obeidat, Ma´en
Okafo, George
Palomäki, Antti
Palotie, Tuula
Pitkäranta, Anne
Pulford, David
Raghavan, Neha
Rahimov, Fedik
Riley-Gillis, Bridget
Rodosthenous, Rodosthenis
Salminen, Eveliina
Salomaa, Veikko
Schleutker, Johanna
Serpi, Raisa
Shen, Huei-yi
Siegel, Richard
Sul, Jae Hoon
Tachmazidou, Ioanna
Tienari, Pentti
Tukiainen, Taru
Vaura, Felix
Virolainen, Petri
Waring, Jeffrey
Waterworth, Dawn
Yang, Robert
Nelis, Mari
Metspalu, Andres
Milani, Lili
Fox, Caroline
Havulinna, Aki S.
Perola, Markus
Jalanko, Anu
Plenge, Robert
Runz, Heiko
Daly, Mark J.
Palotie, Aarno
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_448339
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_448339
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-022-05473-8
