Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 cont...
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
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Author / Creator
Fernandez-Rozadilla, Ceres , Chen, Zhishan , Law, Philip , Thomas, Minta , Díez-Obrero, Virginia , Hsu, Li , Fernandez-Tajes, Juan , Svinti, Victoria , Donnelly, Kevin , Farrington, Susan , Lu, Yingchang , Broderick, Peter , Conti, David , Devall, Mathew , Schumacher, Fredrick , Melas, Marilena , Rennert, Gad , Obón-Santacana, Mireia , Martín-Sánchez, Vicente , Shin, Min-Ho , Shin, Aesun , Kim, Dong-Hyun , Oze, Isao , Tanikawa, Chizu , Ren, Zefang , Gao, Yu-Tang , Jenkins, Mark , Figueiredo, Jane , Gallinger, Steven , Woods, Michael , Newcomb, Polly , Duggan, David , Maughan, Timothy , Kerr, Rachel , Mecklin, Lukka-Pekka , Jousilahti, Pekka , Aaltonen, Lauri , Rissanen, Harri , Eriksson, Johan , Cajuso, Tatiana , Palin, Kimmo , Tanskanen, Tomas , Renkonen-Sinisalo, Laura , Albanes, Demetrius , Weinstein, Stephanie , Platz, Elizabeth , Siegel, Erin , Brezina, Stefanie , Gsur, Andrea , Campbell, Peter , Chang-Claude, Jenny , Castellví-Bel, Sergi , Arndt, Volker , Bishop, Timothy , Idos, Gregory , McDonnell, Kevin , Abu-Ful, Zomoroda , Lejbkowicz, Flavio , Offit, Kenneth , Steinfelder, Robert , van Guelpen, Bethany , Hudson, Thomas , Berndt, Sonja , Hayes, Richard , Pharoah, Paul , Larsson, Susanna , Yen, Yun , Lenz, Heinz-Josef , White, Emily , Li, Li , Pugh, Elizabeth , Cruz-Correa, Marcia , Hunter, David , Nickerson, Deborah , Schoen, Robert , Hampe, Jochen , Edlund, Chistopher , Gauderman, William , Shibata, David , van Duijnhoven, Franzel , Feskens, Edith , Wolk, Alicja , Naccarati, Alessio , Lee, Soo Chin , Bien, Stephanie , Lin, Yi , Bézieau, Stéphane , Tangen, Catherine , Mardis, Elaine , Sawada, Norie , Iwasaki, Motoki , Coetzee, Gerhard , Hayward, Caroline , Deary, Ian , Harris, Sarah , Reid, Stuart , Walker, Marion , Ooi, Li Yin , Zheng, Wei and Peters, Ulrike
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Colorectal cancer (CRC) is a leading cause of mortality worldwide. We conducted a genome-wide association study meta-analysis of 100,204 CRC cases and 154,587 controls of European and east Asian ancestry, identifying 205 independent risk associations, of which 50 were unreported. We performed integrative genomic, transcriptomic and methylomic analy...
Alternative Titles
Full title
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
Authors, Artists and Contributors
Author / Creator
Chen, Zhishan
Law, Philip
Thomas, Minta
Díez-Obrero, Virginia
Hsu, Li
Fernandez-Tajes, Juan
Svinti, Victoria
Donnelly, Kevin
Farrington, Susan
Lu, Yingchang
Broderick, Peter
Conti, David
Devall, Mathew
Schumacher, Fredrick
Melas, Marilena
Rennert, Gad
Obón-Santacana, Mireia
Martín-Sánchez, Vicente
Shin, Min-Ho
Shin, Aesun
Kim, Dong-Hyun
Oze, Isao
Tanikawa, Chizu
Ren, Zefang
Gao, Yu-Tang
Jenkins, Mark
Figueiredo, Jane
Gallinger, Steven
Woods, Michael
Newcomb, Polly
Duggan, David
Maughan, Timothy
Kerr, Rachel
Mecklin, Lukka-Pekka
Jousilahti, Pekka
Aaltonen, Lauri
Rissanen, Harri
Eriksson, Johan
Cajuso, Tatiana
Palin, Kimmo
Tanskanen, Tomas
Renkonen-Sinisalo, Laura
Albanes, Demetrius
Weinstein, Stephanie
Platz, Elizabeth
Siegel, Erin
Brezina, Stefanie
Gsur, Andrea
Campbell, Peter
Chang-Claude, Jenny
Castellví-Bel, Sergi
Arndt, Volker
Bishop, Timothy
Idos, Gregory
McDonnell, Kevin
Abu-Ful, Zomoroda
Lejbkowicz, Flavio
Offit, Kenneth
Steinfelder, Robert
van Guelpen, Bethany
Hudson, Thomas
Berndt, Sonja
Hayes, Richard
Pharoah, Paul
Larsson, Susanna
Yen, Yun
Lenz, Heinz-Josef
White, Emily
Li, Li
Pugh, Elizabeth
Cruz-Correa, Marcia
Hunter, David
Nickerson, Deborah
Schoen, Robert
Hampe, Jochen
Edlund, Chistopher
Gauderman, William
Shibata, David
van Duijnhoven, Franzel
Feskens, Edith
Wolk, Alicja
Naccarati, Alessio
Lee, Soo Chin
Bien, Stephanie
Lin, Yi
Bézieau, Stéphane
Tangen, Catherine
Mardis, Elaine
Sawada, Norie
Iwasaki, Motoki
Coetzee, Gerhard
Hayward, Caroline
Deary, Ian
Harris, Sarah
Reid, Stuart
Walker, Marion
Ooi, Li Yin
Zheng, Wei
Peters, Ulrike
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_448899
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_448899
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-022-01222-9
