C5a receptor inhibitor avacopan in immunoglobulin A nephropathy—an open-label pilot study
C5a receptor inhibitor avacopan in immunoglobulin A nephropathy—an open-label pilot study
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Publisher
England: Oxford University Press
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Language
English
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England: Oxford University Press
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ABSTRACT
Background
Improvement of proteinuria as a marker for disease activity is associated with a better renal outcome in immunoglobulin A nephropathy (IgAN). Complement is an effector pathway in IgA-mediated kidney injury. Avacopan, a selective C5a receptor inhibitor, has previously shown efficacy in anti-neutrophil cytoplasmic antibody–a...
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Full title
C5a receptor inhibitor avacopan in immunoglobulin A nephropathy—an open-label pilot study
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TN_cdi_swepub_primary_oai_swepub_ki_se_453687
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_453687
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ISSN
2048-8505,2048-8513
E-ISSN
2048-8513
DOI
10.1093/ckj/sfab294