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C5a receptor inhibitor avacopan in immunoglobulin A nephropathy—an open-label pilot study

C5a receptor inhibitor avacopan in immunoglobulin A nephropathy—an open-label pilot study

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_453687

C5a receptor inhibitor avacopan in immunoglobulin A nephropathy—an open-label pilot study

About this item

Full title

C5a receptor inhibitor avacopan in immunoglobulin A nephropathy—an open-label pilot study

Publisher

England: Oxford University Press

Journal title

Clinical kidney journal, 2022-05, Vol.15 (5), p.922-928

Language

English

Formats

Publication information

Publisher

England: Oxford University Press

More information

Scope and Contents

Contents

ABSTRACT
Background
Improvement of proteinuria as a marker for disease activity is associated with a better renal outcome in immunoglobulin A nephropathy (IgAN). Complement is an effector pathway in IgA-mediated kidney injury. Avacopan, a selective C5a receptor inhibitor, has previously shown efficacy in anti-neutrophil cytoplasmic antibody–a...

Alternative Titles

Full title

C5a receptor inhibitor avacopan in immunoglobulin A nephropathy—an open-label pilot study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_453687

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_453687

Other Identifiers

ISSN

2048-8505,2048-8513

E-ISSN

2048-8513

DOI

10.1093/ckj/sfab294