Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier i...
Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation
About this item
Full title
Author / Creator
Martínez-Sánchez, Luz del Carmen , Ngo, Phuong Anh , Pradhan, Rashmita , Becker, Lukas-Sebastian , Boehringer, David , Soteriou, Despina , Kubankova, Marketa , Schweitzer, Christine , Koch, Tatyana , Thonn, Veronika , Erkert, Lena , Stolzer, Iris , Günther, Claudia , Becker, Christoph , Weigmann, Benno , Klewer, Monika , Daniel, Christoph , Amann, Kerstin , Tenzer, Stefan , Atreya, Raja , Bergo, Martin , Brakebusch, Cord , Watson, Alastair J M , Guck, Jochen , Fabry, Ben , Atreya, Imke , Neurath, Markus F and López-Posadas, Rocío
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Subjects
More information
Scope and Contents
Contents
ObjectiveIncreased apoptotic shedding has been linked to intestinal barrier dysfunction and development of inflammatory bowel diseases (IBD). In contrast, physiological cell shedding allows the renewal of the epithelial monolayer without compromising the barrier function. Here, we investigated the role of live cell extrusion in epithelial barrier a...
Alternative Titles
Full title
Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation
Authors, Artists and Contributors
Author / Creator
Ngo, Phuong Anh
Pradhan, Rashmita
Becker, Lukas-Sebastian
Boehringer, David
Soteriou, Despina
Kubankova, Marketa
Schweitzer, Christine
Koch, Tatyana
Thonn, Veronika
Erkert, Lena
Stolzer, Iris
Günther, Claudia
Becker, Christoph
Weigmann, Benno
Klewer, Monika
Daniel, Christoph
Amann, Kerstin
Tenzer, Stefan
Atreya, Raja
Bergo, Martin
Brakebusch, Cord
Watson, Alastair J M
Guck, Jochen
Fabry, Ben
Atreya, Imke
Neurath, Markus F
López-Posadas, Rocío
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_455082
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_455082
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2021-325520
