Age, sex and APOE-ε4 modify the balance between soluble and fibrillar β-amyloid in non-demented indi...
Age, sex and APOE-ε4 modify the balance between soluble and fibrillar β-amyloid in non-demented individuals: topographical patterns across two independent cohorts
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Author / Creator
ALFA study , Alzheimer’s Disease Neuroimaging Initiative , for the ALFA study , for the Alzheimer’s Disease Neuroimaging Initiative , Cacciaglia, Raffaele , Salvadó, Gemma , Molinuevo, José Luis , Shekari, Mahnaz , Falcon, Carles , Operto, Gregory , Suárez-Calvet, Marc , Milà-Alomà, Marta , Sala, Arianna , Rodriguez-Vieitez, Elena , Kollmorgen, Gwendlyn , Suridjan, Ivonne , Blennow, Kaj , Zetterberg, Henrik and Gispert, Juan Domingo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Amyloid (Aβ) pathology is the earliest detectable pathophysiological event along the Alzheimer’s
continuum
, which can be measured both in the cerebrospinal fluid (CSF) and by Positron Emission Tomography (PET). Yet, these biomarkers identify two distinct Aβ pools, reflecting the clearance of soluble Aβ as opposed to the presence of Aβ fibril...
Alternative Titles
Full title
Age, sex and APOE-ε4 modify the balance between soluble and fibrillar β-amyloid in non-demented individuals: topographical patterns across two independent cohorts
Authors, Artists and Contributors
Author / Creator
Alzheimer’s Disease Neuroimaging Initiative
for the ALFA study
for the Alzheimer’s Disease Neuroimaging Initiative
Cacciaglia, Raffaele
Salvadó, Gemma
Molinuevo, José Luis
Shekari, Mahnaz
Falcon, Carles
Operto, Gregory
Suárez-Calvet, Marc
Milà-Alomà, Marta
Sala, Arianna
Rodriguez-Vieitez, Elena
Kollmorgen, Gwendlyn
Suridjan, Ivonne
Blennow, Kaj
Zetterberg, Henrik
Gispert, Juan Domingo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_455108
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_455108
Other Identifiers
ISSN
1359-4184,1476-5578
E-ISSN
1476-5578
DOI
10.1038/s41380-022-01436-7
