A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s...
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease
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Author / Creator
Wightman, Douglas P. , Jansen, Iris E. , Savage, Jeanne E. , Shadrin, Alexey A. , Bahrami, Shahram , Holland, Dominic , Rongve, Arvid , Børte, Sigrid , Winsvold, Bendik S. , Drange, Ole Kristian , Martinsen, Amy E. , Skogholt, Anne Heidi , Willer, Cristen , Bråthen, Geir , Bosnes, Ingunn , Nielsen, Jonas Bille , Fritsche, Lars G. , Thomas, Laurent F. , Pedersen, Linda M. , Gabrielsen, Maiken E. , Johnsen, Marianne Bakke , Meisingset, Tore Wergeland , Zhou, Wei , Proitsi, Petroula , Hodges, Angela , Dobson, Richard , Velayudhan, Latha , Heilbron, Karl , Auton, Adam , Sealock, Julia M. , Davis, Lea K. , Pedersen, Nancy L. , Reynolds, Chandra A. , Karlsson, Ida K. , Magnusson, Sigurdur , Stefansson, Hreinn , Thordardottir, Steinunn , Jonsson, Palmi V. , Snaedal, Jon , Zettergren, Anna , Skoog, Ingmar , Kern, Silke , Waern, Margda , Zetterberg, Henrik , Blennow, Kaj , Stordal, Eystein , Hveem, Kristian , Zwart, John-Anker , Athanasiu, Lavinia , Selnes, Per , Saltvedt, Ingvild , Sando, Sigrid B. , Ulstein, Ingun , Djurovic, Srdjan , Fladby, Tormod , Aarsland, Dag , Selbæk, Geir , Ripke, Stephan , Stefansson, Kari , Andreassen, Ole A. , Posthuma, Danielle and 23andMe Research Team
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Late-onset Alzheimer’s disease is a prevalent age-related polygenic disease that accounts for 50–70% of dementia cases. Currently, only a fraction of the genetic variants underlying Alzheimer’s disease have been identified. Here we show that increased sample sizes allowed identification of seven previously unidentified genetic loci contributing to...
Alternative Titles
Full title
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
Jansen, Iris E.
Savage, Jeanne E.
Shadrin, Alexey A.
Bahrami, Shahram
Holland, Dominic
Rongve, Arvid
Børte, Sigrid
Winsvold, Bendik S.
Drange, Ole Kristian
Martinsen, Amy E.
Skogholt, Anne Heidi
Willer, Cristen
Bråthen, Geir
Bosnes, Ingunn
Nielsen, Jonas Bille
Fritsche, Lars G.
Thomas, Laurent F.
Pedersen, Linda M.
Gabrielsen, Maiken E.
Johnsen, Marianne Bakke
Meisingset, Tore Wergeland
Zhou, Wei
Proitsi, Petroula
Hodges, Angela
Dobson, Richard
Velayudhan, Latha
Heilbron, Karl
Auton, Adam
Sealock, Julia M.
Davis, Lea K.
Pedersen, Nancy L.
Reynolds, Chandra A.
Karlsson, Ida K.
Magnusson, Sigurdur
Stefansson, Hreinn
Thordardottir, Steinunn
Jonsson, Palmi V.
Snaedal, Jon
Zettergren, Anna
Skoog, Ingmar
Kern, Silke
Waern, Margda
Zetterberg, Henrik
Blennow, Kaj
Stordal, Eystein
Hveem, Kristian
Zwart, John-Anker
Athanasiu, Lavinia
Selnes, Per
Saltvedt, Ingvild
Sando, Sigrid B.
Ulstein, Ingun
Djurovic, Srdjan
Fladby, Tormod
Aarsland, Dag
Selbæk, Geir
Ripke, Stephan
Stefansson, Kari
Andreassen, Ole A.
Posthuma, Danielle
23andMe Research Team
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_459224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_459224
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-021-00921-z
