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Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven r...

Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven r...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_460082

Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials

About this item

Full title

Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials

Author / Creator

Early Breast Cancer Trialists’ Collaborative group (EBCTCG) , Bradley, Rosie , Braybrooke, Jeremy , Gray, Richard , Hills, Robert , Liu, Zulian , Peto, Richard , Davies, Lucy , Dodwell, David , McGale, Paul , Pan, Hongchao , Taylor, Carolyn , Anderson, Stewart , Gelber, Richard , Gianni, Luca , Jacot, William , Joensuu, Heikki , Moreno-Aspitia, Alvaro , Piccart, Martine , Press, Michael , Romond, Edward , Slamon, Dennis , Suman, Vera , Berry, Richard , Boddington, Clare , Clarke, Mike , Davies, Christina , Duane, Fran , Evans, Vaughan , Gay, Jo , Gettins, Lucy , Godwin, Jon , James, Sam , Liu, Hui , MacKinnon, Elizabeth , Mannu, Gurdeep , McHugh, Theresa , Morris, Philip , Read, Simon , Straiton, Ewan , Wang, Yaochen , Crown, John , de Azambuja, Evandro , Delaloge, Suzette , Fung, Helena , Geyer, Charles , Spielmann, Marc , Valagussa, Pinuccia , Albain, Kathy , Arriagada, Rodrigo , Bartlett, John , Bergsten-Nordström, Elizabeth , Bliss, Judith , Brain, Etienne , Carey, Lisa , Coleman, Robert , Cuzick, Jack , Davidson, Nancy , Del Mastro, Lucia , Di Leo, Angelo , Dignam, James , Dowsett, Mitch , Ejlertsen, Bent , Francis, Prue , Gnant, Michael , Goetz, Matthew , Goodwin, Pam , Halpin-Murphy, Pat , Hayes, Dan , Hill, Catherine , Jagsi, Reshma , Janni, Wolfgang , Loibl, Sibylle , Mamounas, Eleftherios P , Martín, Miguel , Mukai, Hirofumi , Nekljudova, Valentina , Norton, Larry , Ohashi, Yasuo , Pierce, Lori , Poortmans, Philip , Raina, Vinod , Rea, Daniel , Regan, Meredith , Robertson, John , Rutgers, Emiel , Spanic, Tanja , Sparano, Joseph , Steger, Guenther , Tang, Gong , Toi, Masakazu , Tutt, Andrew , Viale, Giuseppe , Wang, Xiang , Whelan, Tim , Wilcken, Nicholas , Wolmark, Norman , Cameron, David , Bergh, Jonas , Pritchard, Kathleen I and Swain, Sandra M

Publisher

England: Elsevier Ltd

Journal title

The lancet oncology, 2021-08, Vol.22 (8), p.1139-1150

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

SummaryBackgroundTrastuzumab targets the extracellular domain of the HER2 protein. Adding trastuzumab to chemotherapy for patients with early-stage, HER2-positive breast cancer reduces the risk of recurrence and death, but is associated with cardiac toxicity. We investigated the long-term benefits and risks of adjuvant trastuzumab on breast cancer...

Alternative Titles

Full title

Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials

Authors, Artists and Contributors

Author / Creator

Early Breast Cancer Trialists’ Collaborative group (EBCTCG)
Bradley, Rosie
Braybrooke, Jeremy
Gray, Richard
Hills, Robert
Liu, Zulian
Peto, Richard
Davies, Lucy
Dodwell, David
McGale, Paul
Pan, Hongchao
Taylor, Carolyn
Anderson, Stewart
Gelber, Richard
Gianni, Luca
Jacot, William
Joensuu, Heikki
Moreno-Aspitia, Alvaro
Piccart, Martine
Press, Michael
Romond, Edward
Slamon, Dennis
Suman, Vera
Berry, Richard
Boddington, Clare
Clarke, Mike
Davies, Christina
Duane, Fran
Evans, Vaughan
Gay, Jo
Gettins, Lucy
Godwin, Jon
James, Sam
Liu, Hui
MacKinnon, Elizabeth
Mannu, Gurdeep
McHugh, Theresa
Morris, Philip
Read, Simon
Straiton, Ewan
Wang, Yaochen
Crown, John
de Azambuja, Evandro
Delaloge, Suzette
Fung, Helena
Geyer, Charles
Spielmann, Marc
Valagussa, Pinuccia
Albain, Kathy
Arriagada, Rodrigo
Bartlett, John
Bergsten-Nordström, Elizabeth
Bliss, Judith
Brain, Etienne
Carey, Lisa
Coleman, Robert
Cuzick, Jack
Davidson, Nancy
Del Mastro, Lucia
Di Leo, Angelo
Dignam, James
Dowsett, Mitch
Ejlertsen, Bent
Francis, Prue
Gnant, Michael
Goetz, Matthew
Goodwin, Pam
Halpin-Murphy, Pat
Hayes, Dan
Hill, Catherine
Jagsi, Reshma
Janni, Wolfgang
Loibl, Sibylle
Mamounas, Eleftherios P
Martín, Miguel
Mukai, Hirofumi
Nekljudova, Valentina
Norton, Larry
Ohashi, Yasuo
Pierce, Lori
Poortmans, Philip
Raina, Vinod
Rea, Daniel
Regan, Meredith
Robertson, John
Rutgers, Emiel
Spanic, Tanja
Sparano, Joseph
Steger, Guenther
Tang, Gong
Toi, Masakazu
Tutt, Andrew
Viale, Giuseppe
Wang, Xiang
Whelan, Tim
Wilcken, Nicholas
Wolmark, Norman
Cameron, David
Bergh, Jonas
Pritchard, Kathleen I
Swain, Sandra M

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_460082

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_460082

Other Identifiers

ISSN

1470-2045

E-ISSN

1474-5488

DOI

10.1016/S1470-2045(21)00288-6

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