Daratumumab-Based Treatment for Immunoglobulin Light-Chain Amyloidosis
Daratumumab-Based Treatment for Immunoglobulin Light-Chain Amyloidosis
About this item
Full title
Author / Creator
Kastritis, Efstathios , Palladini, Giovanni , Minnema, Monique C , Wechalekar, Ashutosh D , Jaccard, Arnaud , Lee, Hans C , Sanchorawala, Vaishali , Gibbs, Simon , Mollee, Peter , Venner, Christopher P , Lu, Jin , Schönland, Stefan , Gatt, Moshe E , Suzuki, Kenshi , Kim, Kihyun , Cibeira, M. Teresa , Beksac, Meral , Libby, Edward , Valent, Jason , Hungria, Vania , Wong, Sandy W , Rosenzweig, Michael , Bumma, Naresh , Huart, Antoine , Dimopoulos, Meletios A , Bhutani, Divaya , Waxman, Adam J , Goodman, Stacey A , Zonder, Jeffrey A , Lam, Selay , Song, Kevin , Hansen, Timon , Manier, Salomon , Roeloffzen, Wilfried , Jamroziak, Krzysztof , Kwok, Fiona , Shimazaki, Chihiro , Kim, Jin-Seok , Crusoe, Edvan , Ahmadi, Tahamtan , Tran, NamPhuong , Qin, Xiang , Vasey, Sandra Y , Tromp, Brenda , Schecter, Jordan M , Weiss, Brendan M , Zhuang, Sen H , Vermeulen, Jessica , Merlini, Giampaolo and Comenzo, Raymond L
Publisher
Boston: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
Boston: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In a randomized trial of bortezomib, cyclophosphamide, and dexamethasone as compared with the same therapy plus daratumumab, patients with light-chain amyloidosis who received daratumumab had a higher frequency of hematologic complete response than those who did not (53.3% vs. 18.1%). Deaths were most commonly due to cardiac failure.
Alternative Titles
Full title
Daratumumab-Based Treatment for Immunoglobulin Light-Chain Amyloidosis
Authors, Artists and Contributors
Author / Creator
Palladini, Giovanni
Minnema, Monique C
Wechalekar, Ashutosh D
Jaccard, Arnaud
Lee, Hans C
Sanchorawala, Vaishali
Gibbs, Simon
Mollee, Peter
Venner, Christopher P
Lu, Jin
Schönland, Stefan
Gatt, Moshe E
Suzuki, Kenshi
Kim, Kihyun
Cibeira, M. Teresa
Beksac, Meral
Libby, Edward
Valent, Jason
Hungria, Vania
Wong, Sandy W
Rosenzweig, Michael
Bumma, Naresh
Huart, Antoine
Dimopoulos, Meletios A
Bhutani, Divaya
Waxman, Adam J
Goodman, Stacey A
Zonder, Jeffrey A
Lam, Selay
Song, Kevin
Hansen, Timon
Manier, Salomon
Roeloffzen, Wilfried
Jamroziak, Krzysztof
Kwok, Fiona
Shimazaki, Chihiro
Kim, Jin-Seok
Crusoe, Edvan
Ahmadi, Tahamtan
Tran, NamPhuong
Qin, Xiang
Vasey, Sandra Y
Tromp, Brenda
Schecter, Jordan M
Weiss, Brendan M
Zhuang, Sen H
Vermeulen, Jessica
Merlini, Giampaolo
Comenzo, Raymond L
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_460903
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_460903
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2028631