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Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibilit...

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibilit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_465431

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

About this item

Full title

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

Author / Creator

Darst, Burcu F. , Sheng, Xin , Olama, Ali Amin Al , Dadaev, Tokhir , Brook, Mark N. , Hoffmann, Thomas J. , Matsuda, Koichi , Wan, Peggy , Tammela, Teuvo L. J. , Giles, Graham G. , MacInnis, Robert J. , Cybulski, Cezary , Wokołorczyk, Dominika , Lubiński, Jan , Hamdy, Freddie C. , Martin, Richard M. , Nordestgaard, Børge G. , Nielsen, Sune F. , Weischer, Maren , Chambers, Suzanne , Horvath, Lisa , Gronberg, Henrik , Aly, Markus , Nordström, Tobias , Pashayan, Nora , Travis, Ruth C. , Riboli, Elio , Lin, Hui-Yi , Mucci, Lorelei A. , Penney, Kathryn L. , Turman, Constance , Tangen, Catherine M. , Fleshner, Neil E. , Finelli, Antonio , Koutros, Stella , Freeman, Laura E. Beane , Wolk, Alicja , Håkansson, Niclas , Hoover, Robert N. , Sørensen, Karina Dalsgaard , Blot, William J. , Zhang, Hong-Wei , Feng, Ninghan , Mao, Xueying , Schaid, Daniel J. , Burnet, Neil , Schnoeller, Thomas , Kibel, Adam S. , Cussenot, Olivier , Cancel-Tassin, Géraldine , Menegaux, Florence , Koudou, Yves Akoli , Stern, Mariana C. , Fachal, Laura , Rosenstein, Barry S. , Ostrer, Harry , Paulo, Paula , Watya, Stephen , Lubwama, Alexander , Llorca, Javier , Multigner, Luc , Kaneva, Radka , Slavov, Chavdar , Mitev, Vanio , Brenner, Hermann , Saum, Kai-Uwe , Klein, Eric A. , Hsing, Ann W. , Kittles, Rick A. , Murphy, Adam B. , Logothetis, Christopher J. , Kim, Jeri , Steele, Linda , Pandha, Hardev , De Ruyck, Kim , Ost, Piet , Xu, Jianfeng , Lim, Jasmine , Teo, Soo-Hwang , Newcomb, Lisa F. , Lin, Daniel W. , Neslund-Dudas, Christine , Rybicki, Benjamin A. , Gamulin, Marija , Lessel, Davor , Singhal, Sandeep , Joniau, Steven , Van den Broeck, Thomas , Martinez, Maria Elena , Larkin, Samantha , Aukim-Hastie, Claire , Bush, William S. , Aldrich, Melinda C. , Crawford, Dana C. , Petrovics, Gyorgy , Casey, Graham , Sanderson, Maureen , Van Den Eeden, Stephen K. , Easton, Douglas F. and Eeles, Rosalind A.

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2021-01, Vol.53 (1), p.65-75

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Prostate cancer is a highly heritable disease with large disparities in incidence rates across ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer genome-wide association studies (107,247 cases and 127,006 controls) and identified 86 new genetic risk variants independently associated with prostate cancer risk, bringi...

Alternative Titles

Full title

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

Authors, Artists and Contributors

Author / Creator

Darst, Burcu F.
Sheng, Xin
Olama, Ali Amin Al
Dadaev, Tokhir
Brook, Mark N.
Hoffmann, Thomas J.
Matsuda, Koichi
Wan, Peggy
Tammela, Teuvo L. J.
Giles, Graham G.
MacInnis, Robert J.
Cybulski, Cezary
Wokołorczyk, Dominika
Lubiński, Jan
Hamdy, Freddie C.
Martin, Richard M.
Nordestgaard, Børge G.
Nielsen, Sune F.
Weischer, Maren
Chambers, Suzanne
Horvath, Lisa
Gronberg, Henrik
Aly, Markus
Nordström, Tobias
Pashayan, Nora
Travis, Ruth C.
Riboli, Elio
Lin, Hui-Yi
Mucci, Lorelei A.
Penney, Kathryn L.
Turman, Constance
Tangen, Catherine M.
Fleshner, Neil E.
Finelli, Antonio
Koutros, Stella
Freeman, Laura E. Beane
Wolk, Alicja
Håkansson, Niclas
Hoover, Robert N.
Sørensen, Karina Dalsgaard
Blot, William J.
Zhang, Hong-Wei
Feng, Ninghan
Mao, Xueying
Schaid, Daniel J.
Burnet, Neil
Schnoeller, Thomas
Kibel, Adam S.
Cussenot, Olivier
Cancel-Tassin, Géraldine
Menegaux, Florence
Koudou, Yves Akoli
Stern, Mariana C.
Fachal, Laura
Rosenstein, Barry S.
Ostrer, Harry
Paulo, Paula
Watya, Stephen
Lubwama, Alexander
Llorca, Javier
Multigner, Luc
Kaneva, Radka
Slavov, Chavdar
Mitev, Vanio
Brenner, Hermann
Saum, Kai-Uwe
Klein, Eric A.
Hsing, Ann W.
Kittles, Rick A.
Murphy, Adam B.
Logothetis, Christopher J.
Kim, Jeri
Steele, Linda
Pandha, Hardev
De Ruyck, Kim
Ost, Piet
Xu, Jianfeng
Lim, Jasmine
Teo, Soo-Hwang
Newcomb, Lisa F.
Lin, Daniel W.
Neslund-Dudas, Christine
Rybicki, Benjamin A.
Gamulin, Marija
Lessel, Davor
Singhal, Sandeep
Joniau, Steven
Van den Broeck, Thomas
Martinez, Maria Elena
Larkin, Samantha
Aukim-Hastie, Claire
Bush, William S.
Aldrich, Melinda C.
Crawford, Dana C.
Petrovics, Gyorgy
Casey, Graham
Sanderson, Maureen
Van Den Eeden, Stephen K.
Easton, Douglas F.
Eeles, Rosalind A.

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_465431

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_465431

Other Identifiers

ISSN

1061-4036,1546-1718

E-ISSN

1546-1718

DOI

10.1038/s41588-020-00748-0