MYC protein stability is negatively regulated by BRD4
MYC protein stability is negatively regulated by BRD4
About this item
Full title
Author / Creator
Publisher
Washington: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
Washington: National Academy of Sciences
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More information
Scope and Contents
Contents
The protooncogene MYC regulates a variety of cellular processes, including proliferation and metabolism. Maintaining MYC at homeostatic levels is critical to normal cell function; overexpression drives many cancers. MYC stability is regulated through phosphorylation: phosphorylation at Thr58 signals degradation while Ser62 phosphorylation leads to...
Alternative Titles
Full title
MYC protein stability is negatively regulated by BRD4
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_470841
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_470841
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1919507117
