Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (L...
Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials
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Author / Creator
Bachert, Claus , Han, Joseph K , Desrosiers, Martin , Hellings, Peter W , Amin, Nikhil , Lee, Stella E , Mullol, Joaquim , Greos, Leon S , Bosso, John V , Laidlaw, Tanya M , Cervin, Anders U , Maspero, Jorge F , Hopkins, Claire , Olze, Heidi , Canonica, G Walter , Paggiaro, Pierluigi , Cho, Seong H , Fokkens, Wytske J , Fujieda, Shigeharu , Zhang, Mei , Lu, Xin , Fan, Chunpeng , Draikiwicz, Steven , Kamat, Siddhesh A , Khan, Asif , Pirozzi, Gianluca , Patel, Naimish , Graham, Neil M H , Ruddy, Marcella , Staudinger, Heribert , Weinreich, David , Stahl, Neil , Yancopoulos, George D and Mannent, Leda P
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) generally have a high symptom burden and poor health-related quality of life, often requiring recurring systemic corticosteroid use and repeated sinus surgery. Dupilumab is a fully human monoclonal antibody that inhibits signalling of interleukin (IL)-4 and IL-13, key drivers of type 2...
Alternative Titles
Full title
Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials
Authors, Artists and Contributors
Author / Creator
Han, Joseph K
Desrosiers, Martin
Hellings, Peter W
Amin, Nikhil
Lee, Stella E
Mullol, Joaquim
Greos, Leon S
Bosso, John V
Laidlaw, Tanya M
Cervin, Anders U
Maspero, Jorge F
Hopkins, Claire
Olze, Heidi
Canonica, G Walter
Paggiaro, Pierluigi
Cho, Seong H
Fokkens, Wytske J
Fujieda, Shigeharu
Zhang, Mei
Lu, Xin
Fan, Chunpeng
Draikiwicz, Steven
Kamat, Siddhesh A
Khan, Asif
Pirozzi, Gianluca
Patel, Naimish
Graham, Neil M H
Ruddy, Marcella
Staudinger, Heribert
Weinreich, David
Stahl, Neil
Yancopoulos, George D
Mannent, Leda P
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_476856
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_476856
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(19)31881-1