AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast canc...
AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer
About this item
Full title
Author / Creator
Kubli, Shawn P. , Bassi, Christian , Roux, Cecilia , Wakeham, Andrew , Göbl, Christoph , Zhou, Wenjing , Jafari, Soode Moghadas , Snow, Bryan , Jones, Lisa , Palomero, Luis , Thu, Kelsie L. , Cassetta, Luca , Soong, Daniel , Berger, Thorsten , Ramachandran, Parameswaran , Baniasadi, Shakiba P. , Duncan, Gordon , Lindzen, Moshit , Yarden, Yosef , Herranz, Carmen , Lazaro, Conxi , Chu, Mandy F. , Haight, Jillian , Tinto, Paul , Silvester, Jennifer , Cescon, David W. , Petit, Anna , Pettersson, Sven , Pollard, Jeffrey W. , Mak, Tak W. , Pujana, Miguel A. , Cappello, Paola and Gorrini, Chiara
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Cancer cells have higher reactive oxygen species (ROS) than normal cells, due to genetic and metabolic alterations. An emerging scenario is that cancer cells increase ROS to activate protumorigenic signaling while activating antioxidant pathways to maintain redox homeostasis. Here we show that, in basal-like and BRCA1-related breast cancer (BC), RO...
Alternative Titles
Full title
AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer
Authors, Artists and Contributors
Author / Creator
Bassi, Christian
Roux, Cecilia
Wakeham, Andrew
Göbl, Christoph
Zhou, Wenjing
Jafari, Soode Moghadas
Snow, Bryan
Jones, Lisa
Palomero, Luis
Thu, Kelsie L.
Cassetta, Luca
Soong, Daniel
Berger, Thorsten
Ramachandran, Parameswaran
Baniasadi, Shakiba P.
Duncan, Gordon
Lindzen, Moshit
Yarden, Yosef
Herranz, Carmen
Lazaro, Conxi
Chu, Mandy F.
Haight, Jillian
Tinto, Paul
Silvester, Jennifer
Cescon, David W.
Petit, Anna
Pettersson, Sven
Pollard, Jeffrey W.
Mak, Tak W.
Pujana, Miguel A.
Cappello, Paola
Gorrini, Chiara
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_482152
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_482152
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1815126116
