Examination of the shared genetic basis of anorexia nervosa and obsessive–compulsive disorder
Examination of the shared genetic basis of anorexia nervosa and obsessive–compulsive disorder
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Author / Creator
Yilmaz, Zeynep , Halvorsen, Matthew , Bryois, Julien , Yu, Dongmei , Thornton, Laura M. , Zerwas, Stephanie , Micali, Nadia , Moessner, Rainald , Burton, Christie L. , Zai, Gwyneth , Erdman, Lauren , Kas, Martien J. , Arnold, Paul D. , Davis, Lea K. , Knowles, James A. , Breen, Gerome , Scharf, Jeremiah M. , Nestadt, Gerald , Mathews, Carol A. , Bulik, Cynthia M. , Mattheisen, Manuel , Crowley, James J. and Eating Disorders Working Group of the Psychiatric Genomics Consortium, Tourette Syndrome/Obsessive–Compulsive Disorder Working Group of the Psychiatric Genomics Consortium
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Anorexia nervosa (AN) and obsessive–compulsive disorder (OCD) are often comorbid and likely to share genetic risk factors. Hence, we examine their shared genetic background using a cross-disorder GWAS meta-analysis of 3495 AN cases, 2688 OCD cases, and 18,013 controls. We confirmed a high genetic correlation between AN and OCD (
r
g
= 0.4...
Alternative Titles
Full title
Examination of the shared genetic basis of anorexia nervosa and obsessive–compulsive disorder
Authors, Artists and Contributors
Author / Creator
Halvorsen, Matthew
Bryois, Julien
Yu, Dongmei
Thornton, Laura M.
Zerwas, Stephanie
Micali, Nadia
Moessner, Rainald
Burton, Christie L.
Zai, Gwyneth
Erdman, Lauren
Kas, Martien J.
Arnold, Paul D.
Davis, Lea K.
Knowles, James A.
Breen, Gerome
Scharf, Jeremiah M.
Nestadt, Gerald
Mathews, Carol A.
Bulik, Cynthia M.
Mattheisen, Manuel
Crowley, James J.
Eating Disorders Working Group of the Psychiatric Genomics Consortium, Tourette Syndrome/Obsessive–Compulsive Disorder Working Group of the Psychiatric Genomics Consortium
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Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_486436
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_486436
Other Identifiers
ISSN
1359-4184,1476-5578
E-ISSN
1476-5578
DOI
10.1038/s41380-018-0115-4