An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cac...
An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice
About this item
Full title
Author / Creator
Rohm, Maria , Schäfer, Michaela , Laurent, Victor , Üstünel, Bilgen Ekim , Niopek, Katharina , Algire, Carolyn , Hautzinger, Oksana , Sijmonsma, Tjeerd P , Zota, Annika , Medrikova, Dasa , Pellegata, Natalia S , Ryden, Mikael , Kulyte, Agné , Dahlman, Ingrid , Arner, Peter , Petrovic, Natasa , Cannon, Barbara , Amri, Ez-Zoubir , Kemp, Bruce E , Steinberg, Gregory R , Janovska, Petra , Kopecky, Jan , Wolfrum, Christian , Blüher, Matthias , Berriel Diaz, Mauricio and Herzig, Stephan
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Cancer cachexia is marked by a pathological loss of fat tissue, but preventing the degradation of AMPK in this tissue helps preserve its mass in mouse models.
Cachexia represents a fatal energy-wasting syndrome in a large number of patients with cancer that mostly results in a pathological loss of skeletal muscle and adipose tissue. Here we show...
Alternative Titles
Full title
An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice
Authors, Artists and Contributors
Author / Creator
Schäfer, Michaela
Laurent, Victor
Üstünel, Bilgen Ekim
Niopek, Katharina
Algire, Carolyn
Hautzinger, Oksana
Sijmonsma, Tjeerd P
Zota, Annika
Medrikova, Dasa
Pellegata, Natalia S
Ryden, Mikael
Kulyte, Agné
Dahlman, Ingrid
Arner, Peter
Petrovic, Natasa
Cannon, Barbara
Amri, Ez-Zoubir
Kemp, Bruce E
Steinberg, Gregory R
Janovska, Petra
Kopecky, Jan
Wolfrum, Christian
Blüher, Matthias
Berriel Diaz, Mauricio
Herzig, Stephan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_502784
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_502784
Other Identifiers
ISSN
1078-8956,1546-170X
E-ISSN
1546-170X
DOI
10.1038/nm.4171
