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Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing

Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_506109

Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing

About this item

Full title

Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2016-06, Vol.17 (6), p.666-676

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Using single-cell transcriptome profiling of pre-granulocyte-macrophage progenitor cells, Nerlov and colleagues identify an early hematopoietic lineage bifurcation that segregates mast cells, eosinophils, megakaryocytes and erythroid cells from monocytes, neutrophils and lymphocytes.
According to current models of hematopoiesis, lymphoid-primed...

Alternative Titles

Full title

Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_506109

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_506109

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.3412