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High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule

High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_509067

High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule

About this item

Full title

High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule

Publisher

England: BioMed Central

Journal title

Molecular medicine (Cambridge, Mass.), 2015-01, Vol.21 Suppl 1 (S1), p.S6-S12

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

High mobility group box protein 1 (HMGB1) is an evolutionary ancient nuclear protein that exerts divergent biological tasks inside and outside of cells. The functions of HMGB1 depend on location, binding partners and redox states of the molecule. In the nucleus, HMGB1 organizes DNA and nucleosomes and regulates gene transcription. Upon cell activat...

Alternative Titles

Full title

High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_509067

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_509067

Other Identifiers

ISSN

1076-1551

E-ISSN

1528-3658

DOI

10.2119/molmed.2015.00087

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