High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule
High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule
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Author / Creator
Publisher
England: BioMed Central
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central
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Scope and Contents
Contents
High mobility group box protein 1 (HMGB1) is an evolutionary ancient nuclear protein that exerts divergent biological tasks inside and outside of cells. The functions of HMGB1 depend on location, binding partners and redox states of the molecule. In the nucleus, HMGB1 organizes DNA and nucleosomes and regulates gene transcription. Upon cell activat...
Alternative Titles
Full title
High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule
Authors, Artists and Contributors
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Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_509067
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_509067
Other Identifiers
ISSN
1076-1551
E-ISSN
1528-3658
DOI
10.2119/molmed.2015.00087