Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases
Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases
About this item
Full title
Author / Creator
Lleó, Alberto , Cavedo, Enrica , Parnetti, Lucilla , Vanderstichele, Hugo , Herukka, Sanna Kaisa , Andreasen, Niels , Ghidoni, Roberta , Lewczuk, Piotr , Jeromin, Andreas , Winblad, Bengt , Tsolaki, Magda , Mroczko, Barbara , Visser, Pieter Jelle , Santana, Isabel , Svenningsson, Per , Blennow, Kaj , Aarsland, Dag , Molinuevo, José Luis , Zetterberg, Henrik and Mollenhauer, Brit
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Key Points
Cerebrospinal fluid (CSF) biomarkers can track relevant pathophysiological changes that occur in the brains of patients with Alzheimer disease (AD)
In AD clinical trials, amyloid-β
1–42
(Aβ
1–42
), total tau (t-tau) and phosphorylated tau (p-tau) are used to measure target engagement, for enrichment or stratification of...
Alternative Titles
Full title
Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases
Authors, Artists and Contributors
Author / Creator
Cavedo, Enrica
Parnetti, Lucilla
Vanderstichele, Hugo
Herukka, Sanna Kaisa
Andreasen, Niels
Ghidoni, Roberta
Lewczuk, Piotr
Jeromin, Andreas
Winblad, Bengt
Tsolaki, Magda
Mroczko, Barbara
Visser, Pieter Jelle
Santana, Isabel
Svenningsson, Per
Blennow, Kaj
Aarsland, Dag
Molinuevo, José Luis
Zetterberg, Henrik
Mollenhauer, Brit
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_516836
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_516836
Other Identifiers
ISSN
1759-4758,1759-4766
E-ISSN
1759-4766
DOI
10.1038/nrneurol.2014.232
