The mutational landscapes of genetic and chemical models of Kras-driven lung cancer
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Whole-exome sequencing is used to compare the mutational landscape of adenomas from three mouse models of non-small-cell lung cancer, induced either by exposure to carcinogens or by genetic mutation of
Kras
; the results reveal that the two types of tumour have different mutational profiles and adopt different routes to tumour development.
Alternative Titles
Full title
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_517909
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_517909
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13898
