Synaptic, transcriptional and chromatin genes disrupted in autism
Synaptic, transcriptional and chromatin genes disrupted in autism
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Author / Creator
DDD Study , UK10K Consortium , Homozygosity Mapping Collaborative for Autism , The Autism Sequencing Consortium , The DDD Study , De Rubeis, Silvia , He, Xin , Goldberg, Arthur P. , Poultney, Christopher S. , Samocha, Kaitlin , Ercument Cicek, A. , Kou, Yan , Liu, Li , Fromer, Menachem , Walker, Susan , Singh, Tarjinder , Klei, Lambertus , Kosmicki, Jack , Fu, Shih-Chen , Aleksic, Branko , Biscaldi, Monica , Bolton, Patrick F. , Brownfeld, Jessica M. , Cai, Jinlu , Campbell, Nicholas G. , Carracedo, Angel , Chahrour, Maria H. , Chiocchetti, Andreas G. , Coon, Hilary , Crawford, Emily L. , Crooks, Lucy , Curran, Sarah R. , Dawson, Geraldine , Duketis, Eftichia , Fernandez, Bridget A. , Gallagher, Louise , Geller, Evan , Guter, Stephen J. , Sean Hill, R. , Ionita-Laza, Iuliana , Jimenez Gonzalez, Patricia , Kilpinen, Helena , Klauck, Sabine M. , Kolevzon, Alexander , Lee, Irene , Lei, Jing , Lehtimäki, Terho , Lin, Chiao-Feng , Ma’ayan, Avi , Marshall, Christian R. , McInnes, Alison L. , Neale, Benjamin , Owen, Michael J. , Ozaki, Norio , Parellada, Mara , Parr, Jeremy R. , Purcell, Shaun , Puura, Kaija , Rajagopalan, Deepthi , Rehnström, Karola , Reichenberg, Abraham , Sabo, Aniko , Sachse, Michael , Sanders, Stephan J. , Schafer, Chad , Schulte-Rüther, Martin , Skuse, David , Stevens, Christine , Szatmari, Peter , Tammimies, Kristiina , Valladares, Otto , Voran, Annette , Wang, Li-San , Weiss, Lauren A. , Jeremy Willsey, A. , Yu, Timothy W. , Yuen, Ryan K. C. , Cook, Edwin H. , Freitag, Christine M. , Gill, Michael , Hultman, Christina M. , Lehner, Thomas , Palotie, Aarno , Schellenberg, Gerard D. , Sklar, Pamela , State, Matthew W. , Sutcliffe, James S. , Walsh, Christopher A. , Scherer, Stephen W. , Zwick, Michael E. , Barrett, Jeffrey C. , Cutler, David J. , Roeder, Kathryn , Devlin, Bernie , Daly, Mark J. and Buxbaum, Joseph D.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The genetic architecture of autism spectrum disorder involves the interplay of common and rare variants and their impact on hundreds of genes. Using exome sequencing, here we show that analysis of rare coding variation in 3,871 autism cases and 9,937 ancestry-matched or parental controls implicates 22 autosomal genes at a false discovery rate (FDR)...
Alternative Titles
Full title
Synaptic, transcriptional and chromatin genes disrupted in autism
Authors, Artists and Contributors
Author / Creator
UK10K Consortium
Homozygosity Mapping Collaborative for Autism
The Autism Sequencing Consortium
The DDD Study
De Rubeis, Silvia
He, Xin
Goldberg, Arthur P.
Poultney, Christopher S.
Samocha, Kaitlin
Ercument Cicek, A.
Kou, Yan
Liu, Li
Fromer, Menachem
Walker, Susan
Singh, Tarjinder
Klei, Lambertus
Kosmicki, Jack
Fu, Shih-Chen
Aleksic, Branko
Biscaldi, Monica
Bolton, Patrick F.
Brownfeld, Jessica M.
Cai, Jinlu
Campbell, Nicholas G.
Carracedo, Angel
Chahrour, Maria H.
Chiocchetti, Andreas G.
Coon, Hilary
Crawford, Emily L.
Crooks, Lucy
Curran, Sarah R.
Dawson, Geraldine
Duketis, Eftichia
Fernandez, Bridget A.
Gallagher, Louise
Geller, Evan
Guter, Stephen J.
Sean Hill, R.
Ionita-Laza, Iuliana
Jimenez Gonzalez, Patricia
Kilpinen, Helena
Klauck, Sabine M.
Kolevzon, Alexander
Lee, Irene
Lei, Jing
Lehtimäki, Terho
Lin, Chiao-Feng
Ma’ayan, Avi
Marshall, Christian R.
McInnes, Alison L.
Neale, Benjamin
Owen, Michael J.
Ozaki, Norio
Parellada, Mara
Parr, Jeremy R.
Purcell, Shaun
Puura, Kaija
Rajagopalan, Deepthi
Rehnström, Karola
Reichenberg, Abraham
Sabo, Aniko
Sachse, Michael
Sanders, Stephan J.
Schafer, Chad
Schulte-Rüther, Martin
Skuse, David
Stevens, Christine
Szatmari, Peter
Tammimies, Kristiina
Valladares, Otto
Voran, Annette
Wang, Li-San
Weiss, Lauren A.
Jeremy Willsey, A.
Yu, Timothy W.
Yuen, Ryan K. C.
Cook, Edwin H.
Freitag, Christine M.
Gill, Michael
Hultman, Christina M.
Lehner, Thomas
Palotie, Aarno
Schellenberg, Gerard D.
Sklar, Pamela
State, Matthew W.
Sutcliffe, James S.
Walsh, Christopher A.
Scherer, Stephen W.
Zwick, Michael E.
Barrett, Jeffrey C.
Cutler, David J.
Roeder, Kathryn
Devlin, Bernie
Daly, Mark J.
Buxbaum, Joseph D.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_517910
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_517910
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13772
