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Mechanisms underlying mutational signatures in human cancers

Mechanisms underlying mutational signatures in human cancers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_520569

Mechanisms underlying mutational signatures in human cancers

About this item

Full title

Mechanisms underlying mutational signatures in human cancers

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Genetics, 2014-09, Vol.15 (9), p.585-598

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
Cancers bear many thousands of mutations that are the product of the biological perturbations or mutational processes that have occurred throughout the development of the disease.
Each mutational process leaves its own characteristic mark of mutations, which is referred to as the mutational signature, on the cancer genome.
Mutat...

Alternative Titles

Full title

Mechanisms underlying mutational signatures in human cancers

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_520569

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_520569

Other Identifiers

ISSN

1471-0056

E-ISSN

1471-0064

DOI

10.1038/nrg3729

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