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Genetics of rheumatoid arthritis contributes to biology and drug discovery

Genetics of rheumatoid arthritis contributes to biology and drug discovery

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_524588

Genetics of rheumatoid arthritis contributes to biology and drug discovery

About this item

Full title

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Author / Creator

RACI consortium , GARNET consortium , the RACI consortium , the GARNET consortium , Okada, Yukinori , Wu, Di , Trynka, Gosia , Raj, Towfique , Terao, Chikashi , Ikari, Katsunori , Kochi, Yuta , Ohmura, Koichiro , Suzuki, Akari , Yoshida, Shinji , Graham, Robert R. , Manoharan, Arun , Ortmann, Ward , Bhangale, Tushar , Denny, Joshua C. , Carroll, Robert J. , Eyler, Anne E. , Greenberg, Jeffrey D. , Kremer, Joel M. , Pappas, Dimitrios A. , Jiang, Lei , Yin, Jian , Ye, Lingying , Su, Ding-Feng , Yang, Jian , Xie, Gang , Keystone, Ed , Westra, Harm-Jan , Esko, Tõnu , Metspalu, Andres , Zhou, Xuezhong , Gupta, Namrata , Mirel, Daniel , Stahl, Eli A. , Diogo, Dorothée , Cui, Jing , Liao, Katherine , Guo, Michael H. , Myouzen, Keiko , Kawaguchi, Takahisa , Coenen, Marieke J. H. , van Riel, Piet L. C. M. , van de Laar, Mart A. F. J. , Guchelaar, Henk-Jan , Huizinga, Tom W. J. , Dieudé, Philippe , Mariette, Xavier , Louis Bridges Jr, S. , Zhernakova, Alexandra , Toes, Rene E. M. , Tak, Paul P. , Miceli-Richard, Corinne , Bang, So-Young , Lee, Hye-Soon , Martin, Javier , Gonzalez-Gay, Miguel A. , Rodriguez-Rodriguez, Luis , Rantapää-Dahlqvist, Solbritt , Ärlestig, Lisbeth , Choi, Hyon K. , Kamatani, Yoichiro , Galan, Pilar , Lathrop, Mark , Eyre, Steve , Bowes, John , Barton, Anne , de Vries, Niek , Moreland, Larry W. , Criswell, Lindsey A. , Karlson, Elizabeth W. , Taniguchi, Atsuo , Yamada, Ryo , Kubo, Michiaki , Liu, Jun S. , Bae, Sang-Cheol , Worthington, Jane , Padyukov, Leonid , Klareskog, Lars , Gregersen, Peter K. , Raychaudhuri, Soumya , Stranger, Barbara E. , De Jager, Philip L. , Franke, Lude , Visscher, Peter M. , Brown, Matthew A. , Yamanaka, Hisashi , Mimori, Tsuneyo , Takahashi, Atsushi , Xu, Huji , Behrens, Timothy W. , Siminovitch, Katherine A. , Momohara, Shigeki , Matsuda, Fumihiko , Yamamoto, Kazuhiko and Plenge, Robert M.

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2014-02, Vol.506 (7488), p.376-381

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A genome-wide association study meta-analysis of more than 100,000 subjects of European and Asian ancestries reveals 42 new risk loci for rheumatoid arthritis, with follow-up studies identifying 98 biological candidate genes that are either already being targeted by drugs or could be in the future.
Rheumatoid arthritis drug targets
Virtual sc...

Alternative Titles

Full title

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Authors, Artists and Contributors

Author / Creator

RACI consortium
GARNET consortium
the RACI consortium
the GARNET consortium
Okada, Yukinori
Wu, Di
Trynka, Gosia
Raj, Towfique
Terao, Chikashi
Ikari, Katsunori
Kochi, Yuta
Ohmura, Koichiro
Suzuki, Akari
Yoshida, Shinji
Graham, Robert R.
Manoharan, Arun
Ortmann, Ward
Bhangale, Tushar
Denny, Joshua C.
Carroll, Robert J.
Eyler, Anne E.
Greenberg, Jeffrey D.
Kremer, Joel M.
Pappas, Dimitrios A.
Jiang, Lei
Yin, Jian
Ye, Lingying
Su, Ding-Feng
Yang, Jian
Xie, Gang
Keystone, Ed
Westra, Harm-Jan
Esko, Tõnu
Metspalu, Andres
Zhou, Xuezhong
Gupta, Namrata
Mirel, Daniel
Stahl, Eli A.
Diogo, Dorothée
Cui, Jing
Liao, Katherine
Guo, Michael H.
Myouzen, Keiko
Kawaguchi, Takahisa
Coenen, Marieke J. H.
van Riel, Piet L. C. M.
van de Laar, Mart A. F. J.
Guchelaar, Henk-Jan
Huizinga, Tom W. J.
Dieudé, Philippe
Mariette, Xavier
Louis Bridges Jr, S.
Zhernakova, Alexandra
Toes, Rene E. M.
Tak, Paul P.
Miceli-Richard, Corinne
Bang, So-Young
Lee, Hye-Soon
Martin, Javier
Gonzalez-Gay, Miguel A.
Rodriguez-Rodriguez, Luis
Rantapää-Dahlqvist, Solbritt
Ärlestig, Lisbeth
Choi, Hyon K.
Kamatani, Yoichiro
Galan, Pilar
Lathrop, Mark
Eyre, Steve
Bowes, John
Barton, Anne
de Vries, Niek
Moreland, Larry W.
Criswell, Lindsey A.
Karlson, Elizabeth W.
Taniguchi, Atsuo
Yamada, Ryo
Kubo, Michiaki
Liu, Jun S.
Bae, Sang-Cheol
Worthington, Jane
Padyukov, Leonid
Klareskog, Lars
Gregersen, Peter K.
Raychaudhuri, Soumya
Stranger, Barbara E.
De Jager, Philip L.
Franke, Lude
Visscher, Peter M.
Brown, Matthew A.
Yamanaka, Hisashi
Mimori, Tsuneyo
Takahashi, Atsushi
Xu, Huji
Behrens, Timothy W.
Siminovitch, Katherine A.
Momohara, Shigeki
Matsuda, Fumihiko
Yamamoto, Kazuhiko
Plenge, Robert M.

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_524588

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_524588

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/nature12873