Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
About this item
Full title
Author / Creator
Tsoi, Lam C , Spain, Sarah L , Knight, Jo , Ellinghaus, Eva , Stuart, Philip E , Capon, Francesca , Ding, Jun , Li, Yanming , Tejasvi, Trilokraj , Gudjonsson, Johann E , Kang, Hyun M , Allen, Michael H , McManus, Ross , Novelli, Giuseppe , Samuelsson, Lena , Schalkwijk, Joost , Ståhle, Mona , Burden, A David , Smith, Catherine H , Cork, Michael J , Estivill, Xavier , Bowcock, Anne M , Krueger, Gerald G , Weger, Wolfgang , Worthington, Jane , Tazi-Ahnini, Rachid , Nestle, Frank O , Hayday, Adrian , Hoffmann, Per , Winkelmann, Juliane , Wijmenga, Cisca , Langford, Cordelia , Edkins, Sarah , Andrews, Robert , Blackburn, Hannah , Strange, Amy , Band, Gavin , Pearson, Richard D , Vukcevic, Damjan , Spencer, Chris C A , Deloukas, Panos , Mrowietz, Ulrich , Schreiber, Stefan , Weidinger, Stephan , Koks, Sulev , Kingo, Külli , Esko, Tonu , Metspalu, Andres , Lim, Henry W , Voorhees, John J , Weichenthal, Michael , Wichmann, H Erich , Chandran, Vinod , Rosen, Cheryl F , Rahman, Proton , Gladman, Dafna D , Griffiths, Christopher E M , Reis, Andre , Kere, Juha , Nair, Rajan P , Franke, Andre , Barker, Jonathan N W N , Abecasis, Goncalo R , Elder, James T , Trembath, Richard C , Psoriasis Association Genetics Extension , Genetic Analysis of Psoriasis Consortium , Collaborative Association Study of Psoriasis (CASP) and Wellcome Trust Case Control Consortium 2
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Richard Trembath and colleagues report a meta-analysis of genome-wide association studies for psoriasis, including 2 cohorts genotyped on the custom Immunochip array, in a total of 10,588 cases and 22,806 controls. They identify 15 new susceptibility loci and refine signals in previously known loci, highlighting a role for innate host defense in su...
Alternative Titles
Full title
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
Authors, Artists and Contributors
Author / Creator
Spain, Sarah L
Knight, Jo
Ellinghaus, Eva
Stuart, Philip E
Capon, Francesca
Ding, Jun
Li, Yanming
Tejasvi, Trilokraj
Gudjonsson, Johann E
Kang, Hyun M
Allen, Michael H
McManus, Ross
Novelli, Giuseppe
Samuelsson, Lena
Schalkwijk, Joost
Ståhle, Mona
Burden, A David
Smith, Catherine H
Cork, Michael J
Estivill, Xavier
Bowcock, Anne M
Krueger, Gerald G
Weger, Wolfgang
Worthington, Jane
Tazi-Ahnini, Rachid
Nestle, Frank O
Hayday, Adrian
Hoffmann, Per
Winkelmann, Juliane
Wijmenga, Cisca
Langford, Cordelia
Edkins, Sarah
Andrews, Robert
Blackburn, Hannah
Strange, Amy
Band, Gavin
Pearson, Richard D
Vukcevic, Damjan
Spencer, Chris C A
Deloukas, Panos
Mrowietz, Ulrich
Schreiber, Stefan
Weidinger, Stephan
Koks, Sulev
Kingo, Külli
Esko, Tonu
Metspalu, Andres
Lim, Henry W
Voorhees, John J
Weichenthal, Michael
Wichmann, H Erich
Chandran, Vinod
Rosen, Cheryl F
Rahman, Proton
Gladman, Dafna D
Griffiths, Christopher E M
Reis, Andre
Kere, Juha
Nair, Rajan P
Franke, Andre
Barker, Jonathan N W N
Abecasis, Goncalo R
Elder, James T
Trembath, Richard C
Psoriasis Association Genetics Extension
Genetic Analysis of Psoriasis Consortium
Collaborative Association Study of Psoriasis (CASP)
Wellcome Trust Case Control Consortium 2
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_533444
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_533444
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/ng.2467
