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Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_534754

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

About this item

Full title

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

Author / Creator

Wellcome Trust Case Control Consortium 2 , Esophageal Adenocarcinoma Genetics Consortium , The Wellcome Trust Case Control Consortium 2 , The Esophageal Adenocarcinoma Genetics Consortium , Gay, Laura J , Palles, Claire , Band, Gavin , Whiteman, David C , Lescai, Francesco , Langford, Cordelia , Nanji, Manoj , Edkins, Sarah , van der Winkel, Anouk , Sasieni, Peter , Howarth, Kimberley , Pirinen, Matti , Peppelenbosch, Maikel P , Kuipers, Ernst J , Peters, Wilbert H , Reynolds, John V , Kelleher, Dermot P , McManus, Ross , Grabsch, Heike , Prenen, Hans , Krishnadath, Kausila , Siersema, Peter D , van Baal, Jantine W P M , Middleton, Mark , Petty, Russell , Burch, Nicola , Bhandari, Pradeep , Edwards, Cathryn , Penman, Ian , Murray, Iain , Mullins, Paul , Wu, Anna H , Bird, Nigel C , Dallal, Helen , Shaheen, Nicholas J , Bernstein, Leslie , Corley, Douglas A , Reid, Brian J , Gammon, Marilie D , Smart, Howard , Dhar, Anjan , McMurtry, Hugh , Ali, Haythem , Liu, Geoffrey , Rutter, Matt , Tawil, Ashref , Morris, Danielle , Nwokolo, Chuka , Isaacs, Peter , Rodgers, Colin , Ragunath, Krish , MacDonald, Chris , Monk, David , Wajed, Saj , Johnston, David , Gibbons, Michael , Church, Nicholas , Langley, Ruth , Griffin, Michael , Alderson, Derek , Hunt, Sarah E , Gray, Emma , Dronov, Serge , Potter, Simon C , Tashakkori-Ghanbaria, Avazeh , Brooks, Claire , Bramon, Elvira , Brown, Matthew A , Casas, Juan P , Corvin, Aiden , Duncanson, Audrey , Markus, Hugh S , Mathew, Christopher G , Palmer, Colin N A , Plomin, Robert , Rautanen, Anna , Trembath, Richard C , Viswanathan, Ananth C , Wood, Nicholas , Trynka, Gosia , Wijmenga, Cisca , Cazier, Jean-Baptiste , Gellatly, Nichola L , Glancy, Deborah , Cooper, Sheldon C , Cunningham, David , Hapeshi, Julie , Ferry, David , Rathbone, Barrie , MacGregor, Stuart , Watson, Peter , Sanders, Scott , Ek, Weronica , Harrison, Rebecca F , de Caestecker, John , Barr, Hugh , Vaughan, Thomas L , Peltonen, Leena , Spencer, Chris C A and Jankowski, Janusz A Z

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2012-10, Vol.44 (10), p.1131-1136

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Peter Donnelly and colleagues report a genome-wide association study for Barrett's esophagus, a common premalignant condition associated with stomach acid reflux and predisposing to esophageal adenocarcinoma. They identify two loci associated with susceptibility to Barrett's esophagus.
Barrett's esophagus is an increasingly common disease that i...

Alternative Titles

Full title

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

Authors, Artists and Contributors

Author / Creator

Wellcome Trust Case Control Consortium 2
Esophageal Adenocarcinoma Genetics Consortium
The Wellcome Trust Case Control Consortium 2
The Esophageal Adenocarcinoma Genetics Consortium
Gay, Laura J
Palles, Claire
Band, Gavin
Whiteman, David C
Lescai, Francesco
Langford, Cordelia
Nanji, Manoj
Edkins, Sarah
van der Winkel, Anouk
Sasieni, Peter
Howarth, Kimberley
Pirinen, Matti
Peppelenbosch, Maikel P
Kuipers, Ernst J
Peters, Wilbert H
Reynolds, John V
Kelleher, Dermot P
McManus, Ross
Grabsch, Heike
Prenen, Hans
Krishnadath, Kausila
Siersema, Peter D
van Baal, Jantine W P M
Middleton, Mark
Petty, Russell
Burch, Nicola
Bhandari, Pradeep
Edwards, Cathryn
Penman, Ian
Murray, Iain
Mullins, Paul
Wu, Anna H
Bird, Nigel C
Dallal, Helen
Shaheen, Nicholas J
Bernstein, Leslie
Corley, Douglas A
Reid, Brian J
Gammon, Marilie D
Smart, Howard
Dhar, Anjan
McMurtry, Hugh
Ali, Haythem
Liu, Geoffrey
Rutter, Matt
Tawil, Ashref
Morris, Danielle
Nwokolo, Chuka
Isaacs, Peter
Rodgers, Colin
Ragunath, Krish
MacDonald, Chris
Monk, David
Wajed, Saj
Johnston, David
Gibbons, Michael
Church, Nicholas
Langley, Ruth
Griffin, Michael
Alderson, Derek
Hunt, Sarah E
Gray, Emma
Dronov, Serge
Potter, Simon C
Tashakkori-Ghanbaria, Avazeh
Brooks, Claire
Bramon, Elvira
Brown, Matthew A
Casas, Juan P
Corvin, Aiden
Duncanson, Audrey
Markus, Hugh S
Mathew, Christopher G
Palmer, Colin N A
Plomin, Robert
Rautanen, Anna
Trembath, Richard C
Viswanathan, Ananth C
Wood, Nicholas
Trynka, Gosia
Wijmenga, Cisca
Cazier, Jean-Baptiste
Gellatly, Nichola L
Glancy, Deborah
Cooper, Sheldon C
Cunningham, David
Hapeshi, Julie
Ferry, David
Rathbone, Barrie
MacGregor, Stuart
Watson, Peter
Sanders, Scott
Ek, Weronica
Harrison, Rebecca F
de Caestecker, John
Barr, Hugh
Vaughan, Thomas L
Peltonen, Leena
Spencer, Chris C A
Jankowski, Janusz A Z

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_534754

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_534754

Other Identifiers

ISSN

1061-4036,1546-1718

E-ISSN

1546-1718

DOI

10.1038/ng.2408