A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure
A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure
About this item
Full title
Author / Creator
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Subjects
More information
Scope and Contents
Contents
The ubiquitin ligases RNF8 and RNF168 orchestrate DNA damage signalling through the ubiquitylation of histone H2A and the recruitment of downstream repair factors. Here, we demonstrate that RNF8, but not RNF168 or the canonical H2A ubiquitin ligase RNF2, mediates extensive chromatin decondensation. Our data show that CHD4, the catalytic subunit of...
Alternative Titles
Full title
A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_537550
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_537550
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2012.104
