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Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer r...

Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer r...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_555397

Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment

About this item

Full title

Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

Journal title

Human genetics, 2010-01, Vol.127 (1), p.1-17

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

More information

Scope and Contents

Contents

The cytochromes P450 (CYPs) are very efficient catalysts of foreign compound metabolism and are responsible for the major part of metabolism of clinically important drugs. The enzymes are important in cancer since they (a) activate dietary and environmental components to ultimate carcinogens, (b) activate or inactivate drugs used for cancer treatme...

Alternative Titles

Full title

Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_555397

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_555397

Other Identifiers

ISSN

0340-6717,1432-1203

E-ISSN

1432-1203

DOI

10.1007/s00439-009-0748-0