Allele-specific expression and gene methylation in the control of CYP1A2 mRNA level in human livers
Allele-specific expression and gene methylation in the control of CYP1A2 mRNA level in human livers
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The basis for interindividual variation in the
CYP1A2
gene expression is not fully understood and the known genetic polymorphisms in the gene provide no explanation. We investigated whether the
CYP1A2
gene expression is regulated by DNA methylation and displays allele-specific expression (ASE) using 65 human livers. Forty-eight percent...
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Full title
Allele-specific expression and gene methylation in the control of CYP1A2 mRNA level in human livers
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TN_cdi_swepub_primary_oai_swepub_ki_se_559254
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_559254
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ISSN
1470-269X,1473-1150
E-ISSN
1473-1150
DOI
10.1038/tpj.2009.4