High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic diseas...
High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease
About this item
Full title
Author / Creator
Publisher
England: National Library of Medicine - MEDLINE Abstracts
Journal title
Language
English
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Publication information
Publisher
England: National Library of Medicine - MEDLINE Abstracts
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More information
Scope and Contents
Contents
High-mobility group box protein 1 (HMGB1) is a non-histone nuclear protein that has a dual function. Inside the cell, HMGB1 binds DNA, regulating transcription and determining chromosomal architecture. Outside the cell, HMGB1 can serve as an alarmin to activate the innate system and mediate a wide range of physiological and pathological responses....
Alternative Titles
Full title
High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_563465
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_563465
Other Identifiers
ISSN
1478-6354
E-ISSN
1478-6362
DOI
10.1186/ar2440
