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The pro-inflammatory effect of HMGB1, a mediator of inflammation in arthritis, is dependent on the r...

The pro-inflammatory effect of HMGB1, a mediator of inflammation in arthritis, is dependent on the r...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_608478

The pro-inflammatory effect of HMGB1, a mediator of inflammation in arthritis, is dependent on the redox status of the protein

About this item

Full title

The pro-inflammatory effect of HMGB1, a mediator of inflammation in arthritis, is dependent on the redox status of the protein

Publisher

Kidlington: BMJ Publishing Group Ltd and European League Against Rheumatism

Journal title

Annals of the rheumatic diseases, 2012-02, Vol.71 (Suppl 1), p.A81-A82

Language

English

Formats

Publication information

Publisher

Kidlington: BMJ Publishing Group Ltd and European League Against Rheumatism

More information

Scope and Contents

Contents

Background and objectives High mobility group box protein 1 (HMGB1) is a nuclear protein involved in chromatin architecture and is present in all cells. HMGB1 also functions as a prototype alarmin and is released passively during necrotic cell death, as well as actively secreted from certain immunocompetent cells. Levels of HMGB1 are highly elevate...

Alternative Titles

Full title

The pro-inflammatory effect of HMGB1, a mediator of inflammation in arthritis, is dependent on the redox status of the protein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_608478

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_608478

Other Identifiers

ISSN

0003-4967

E-ISSN

1468-2060

DOI

10.1136/annrheumdis-2011-201238.22

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