GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, compli...
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification
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Author / Creator
Lagou, Vasiliki , Jiang, Longda , Ulrich, Anna , Zudina, Liudmila , González, Karla Sofia Gutiérrez , Balkhiyarova, Zhanna , Faggian, Alessia , Maina, Jared G. , Chen, Shiqian , Todorov, Petar V. , Sharapov, Sodbo , David, Alessia , Marullo, Letizia , Mägi, Reedik , Rujan, Roxana-Maria , Ahlqvist, Emma , Thorleifsson, Gudmar , Gao, Ηe , Εvangelou, Εvangelos , Benyamin, Beben , Scott, Robert A. , Isaacs, Aaron , Zhao, Jing Hua , Willems, Sara M. , Johnson, Toby , Gieger, Christian , Grallert, Harald , Meisinger, Christa , Müller-Nurasyid, Martina , Strawbridge, Rona J. , Goel, Anuj , Rybin, Denis , Albrecht, Eva , Jackson, Anne U. , Stringham, Heather M. , Corrêa, Ivan R. , Farber-Eger, Eric , Steinthorsdottir, Valgerdur , Uitterlinden, André G. , Munroe, Patricia B. , Brown, Morris J. , Schmidberger, Julian , Holmen, Oddgeir , Thorand, Barbara , Hveem, Kristian , Wilsgaard, Tom , Mohlke, Karen L. , Wang, Zhe , Shmeliov, Aleksey , den Hoed, Marcel , Loos, Ruth J. F. , Kratzer, Wolfgang , Haenle, Mark , Koenig, Wolfgang , Boehm, Bernhard O. , Tan, Tricia M. , Tomas, Alejandra , Salem, Victoria , Barroso, Inês , Tuomilehto, Jaakko , Boehnke, Michael , Florez, Jose C. , Hamsten, Anders , Watkins, Hugh , Njølstad, Inger , Wichmann, H.-Erich , Caulfield, Mark J. , Khaw, Kay-Tee , van Duijn, Cornelia M. , Hofman, Albert , Wareham, Nicholas J. , Langenberg, Claudia , Whitfield, John B. , Martin, Nicholas G. , Montgomery, Grant , Scapoli, Chiara , Tzoulaki, Ioanna , Elliott, Paul , Thorsteinsdottir, Unnur , Stefansson, Kari , Brittain, Evan L. , McCarthy, Mark I. , Froguel, Philippe , Sexton, Patrick M. , Wootten, Denise , Groop, Leif , Dupuis, Josée , Meigs, James B. , Deganutti, Giuseppe , Demirkan, Ayse , Pers, Tune H. , Reynolds, Christopher A. , Aulchenko, Yurii S. , Kaakinen, Marika A. , Jones, Ben , Prokopenko, Inga , Meta-Analysis of Glucose and Insulin-Related Traits Consortium (MAGIC) , GWA-PA Consortium , Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) , Faculty of Medicine , Medicinska fakulteten , Strategiska forskningsområden (SFO) , Translationell muskelforskning , Institutionen för kliniska vetenskaper, Malmö , Strategic research areas (SRA) , Lunds universitet , Translational Muscle Research , Profilområden och andra starka forskningsmiljöer , Lund University , EXODIAB: Excellence of Diabetes Research in Sweden , Profile areas and other strong research environments and Department of Clinical Sciences, Malmö
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Conventional measurements of fasting and postprandial blood glucose levels investigated in genome-wide association studies (GWAS) cannot capture the effects of DNA variability on ‘around the clock’ glucoregulatory processes. Here we show that GWAS meta-analysis of glucose measurements under nonstandardized conditions (random glucose (RG)) in 476,32...
Alternative Titles
Full title
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification
Authors, Artists and Contributors
Author / Creator
Jiang, Longda
Ulrich, Anna
Zudina, Liudmila
González, Karla Sofia Gutiérrez
Balkhiyarova, Zhanna
Faggian, Alessia
Maina, Jared G.
Chen, Shiqian
Todorov, Petar V.
Sharapov, Sodbo
David, Alessia
Marullo, Letizia
Mägi, Reedik
Rujan, Roxana-Maria
Ahlqvist, Emma
Thorleifsson, Gudmar
Gao, Ηe
Εvangelou, Εvangelos
Benyamin, Beben
Scott, Robert A.
Isaacs, Aaron
Zhao, Jing Hua
Willems, Sara M.
Johnson, Toby
Gieger, Christian
Grallert, Harald
Meisinger, Christa
Müller-Nurasyid, Martina
Strawbridge, Rona J.
Goel, Anuj
Rybin, Denis
Albrecht, Eva
Jackson, Anne U.
Stringham, Heather M.
Corrêa, Ivan R.
Farber-Eger, Eric
Steinthorsdottir, Valgerdur
Uitterlinden, André G.
Munroe, Patricia B.
Brown, Morris J.
Schmidberger, Julian
Holmen, Oddgeir
Thorand, Barbara
Hveem, Kristian
Wilsgaard, Tom
Mohlke, Karen L.
Wang, Zhe
Shmeliov, Aleksey
den Hoed, Marcel
Loos, Ruth J. F.
Kratzer, Wolfgang
Haenle, Mark
Koenig, Wolfgang
Boehm, Bernhard O.
Tan, Tricia M.
Tomas, Alejandra
Salem, Victoria
Barroso, Inês
Tuomilehto, Jaakko
Boehnke, Michael
Florez, Jose C.
Hamsten, Anders
Watkins, Hugh
Njølstad, Inger
Wichmann, H.-Erich
Caulfield, Mark J.
Khaw, Kay-Tee
van Duijn, Cornelia M.
Hofman, Albert
Wareham, Nicholas J.
Langenberg, Claudia
Whitfield, John B.
Martin, Nicholas G.
Montgomery, Grant
Scapoli, Chiara
Tzoulaki, Ioanna
Elliott, Paul
Thorsteinsdottir, Unnur
Stefansson, Kari
Brittain, Evan L.
McCarthy, Mark I.
Froguel, Philippe
Sexton, Patrick M.
Wootten, Denise
Groop, Leif
Dupuis, Josée
Meigs, James B.
Deganutti, Giuseppe
Demirkan, Ayse
Pers, Tune H.
Reynolds, Christopher A.
Aulchenko, Yurii S.
Kaakinen, Marika A.
Jones, Ben
Prokopenko, Inga
Meta-Analysis of Glucose and Insulin-Related Traits Consortium (MAGIC)
GWA-PA Consortium
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)
Faculty of Medicine
Medicinska fakulteten
Strategiska forskningsområden (SFO)
Translationell muskelforskning
Institutionen för kliniska vetenskaper, Malmö
Strategic research areas (SRA)
Lunds universitet
Translational Muscle Research
Profilområden och andra starka forskningsmiljöer
Lund University
EXODIAB: Excellence of Diabetes Research in Sweden
Profile areas and other strong research environments
Department of Clinical Sciences, Malmö
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_645167
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_645167
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-023-01462-3
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