Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency
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Author / Creator
NF-κB Consortium , COVID Human Genetic Effort , Le Voyer, Tom , Parent, Audrey V. , Liu, Xian , Cederholm, Axel , Gervais, Adrian , Rosain, Jérémie , Nguyen, Tina , Perez Lorenzo, Malena , Rinchai, Darawan , Zhang, Peng , Hancioglu, Gonca , Ghillani-Dalbin, Pascale , Charuel, Jean-Luc , Philippot, Quentin , Gueye, Mame Sokhna , Soudée, Camille , Rozenberg, Flore , Momenilandi, Mana , Riller, Quentin , Delmonte, Ottavia M. , Müller, Gabriele , Keller, Baerbel , Orrego, Julio , Rubin, Tamar , Emiroglu, Melike , Eriksson, Daniel , Katelaris, Constance H. , Mustillo, Peter , Raedler, Johannes , Bohlen, Jonathan , Bengi Celik, Jale , Astudillo, Camila , Winter, Sarah , Guffroy, Aurélien , DeRisi, Joseph L. , Yu, David , Miller, Corey , Feng, Yi , Guichard, Audrey , Béziat, Vivien , Bustamante, Jacinta , Pan-Hammarström, Qiang , Rosen, Lindsey B. , Bosticardo, Marita , Kenney, Heather , Castagnoli, Riccardo , Slade, Charlotte A. , Boztuğ, Kaan , Latour, Sylvain , Sediva, Anna , Atschekzei, Faranaz , Sogkas, Georgios , Poli, M. Cecilia , Palterer, Boaz , Keller, Michael D. , Pinzon-Charry, Alberto , Sullivan, Anna , Droney, Luke , Suan, Daniel , Wong, Melanie , Ma, Cindy , Dalal, Ilan , Hie, Miguel , Lazaro, Estibaliz , Franco, Jose , Malphettes, Marion , Pasquet, Marlene , Maccari, Maria Elena , Frosk, Patrick , Goodnow, Christopher C. , Gray, Paul E. , Belot, Alexandre , Kuehn, Hye Sun , Servettaz, Amélie , Barlogis, Vincent , Le Guenno, Guillaume , Herrmann, Vera-Maria , Kuijpers, Taco , Ducoux, Grégoire , Sarrot-Reynauld, Françoise , Schuetz, Catharina , Cunningham-Rundles, Charlotte , Rieux-Laucat, Frédéric , Tangye, Stuart G. , Doffinger, Rainer , Grimbacher, Bodo , Berteloot, Laureline , Trouillet Assant, Sophie , Su, Helen , Abel, Laurent , Zhang, Qian , Boisson, Bertrand , Cobat, Aurélie , Jouanguy, Emmanuelle , Kampe, Olle , Bastard, Paul , Roifman, Chaim M. , Notarangelo, Luigi D. , Anderson, Mark S. and Casanova, Jean-Laurent
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Patients with autoimmune polyendocrinopathy syndrome type 1 (APS-1) caused by autosomal recessive AIRE deficiency produce autoantibodies that neutralize type I interferons (IFNs)
1
,
2
, conferring a predisposition to life-threatening COVID-19 pneumonia
3
. Here we report that patients with autosomal recessive NIK or RELB deficien...
Alternative Titles
Full title
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency
Authors, Artists and Contributors
Author / Creator
COVID Human Genetic Effort
Le Voyer, Tom
Parent, Audrey V.
Liu, Xian
Cederholm, Axel
Gervais, Adrian
Rosain, Jérémie
Nguyen, Tina
Perez Lorenzo, Malena
Rinchai, Darawan
Zhang, Peng
Hancioglu, Gonca
Ghillani-Dalbin, Pascale
Charuel, Jean-Luc
Philippot, Quentin
Gueye, Mame Sokhna
Soudée, Camille
Rozenberg, Flore
Momenilandi, Mana
Riller, Quentin
Delmonte, Ottavia M.
Müller, Gabriele
Keller, Baerbel
Orrego, Julio
Rubin, Tamar
Emiroglu, Melike
Eriksson, Daniel
Katelaris, Constance H.
Mustillo, Peter
Raedler, Johannes
Bohlen, Jonathan
Bengi Celik, Jale
Astudillo, Camila
Winter, Sarah
Guffroy, Aurélien
DeRisi, Joseph L.
Yu, David
Miller, Corey
Feng, Yi
Guichard, Audrey
Béziat, Vivien
Bustamante, Jacinta
Pan-Hammarström, Qiang
Rosen, Lindsey B.
Bosticardo, Marita
Kenney, Heather
Castagnoli, Riccardo
Slade, Charlotte A.
Boztuğ, Kaan
Latour, Sylvain
Sediva, Anna
Atschekzei, Faranaz
Sogkas, Georgios
Poli, M. Cecilia
Palterer, Boaz
Keller, Michael D.
Pinzon-Charry, Alberto
Sullivan, Anna
Droney, Luke
Suan, Daniel
Wong, Melanie
Ma, Cindy
Dalal, Ilan
Hie, Miguel
Lazaro, Estibaliz
Franco, Jose
Malphettes, Marion
Pasquet, Marlene
Maccari, Maria Elena
Frosk, Patrick
Goodnow, Christopher C.
Gray, Paul E.
Belot, Alexandre
Kuehn, Hye Sun
Servettaz, Amélie
Barlogis, Vincent
Le Guenno, Guillaume
Herrmann, Vera-Maria
Kuijpers, Taco
Ducoux, Grégoire
Sarrot-Reynauld, Françoise
Schuetz, Catharina
Cunningham-Rundles, Charlotte
Rieux-Laucat, Frédéric
Tangye, Stuart G.
Doffinger, Rainer
Grimbacher, Bodo
Berteloot, Laureline
Trouillet Assant, Sophie
Su, Helen
Abel, Laurent
Zhang, Qian
Boisson, Bertrand
Cobat, Aurélie
Jouanguy, Emmanuelle
Kampe, Olle
Bastard, Paul
Roifman, Chaim M.
Notarangelo, Luigi D.
Anderson, Mark S.
Casanova, Jean-Laurent
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_831466
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_831466
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06717-x
