Improved OMV vaccine against Neisseria meningitidis using genetically engineered strains and a deter...
Improved OMV vaccine against Neisseria meningitidis using genetically engineered strains and a detergent-free purification process
About this item
Full title
Author / Creator
Publisher
Kidlington: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Kidlington: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Abstract The use of detergent-extracted outer membrane vesicles (OMVs) is an established approach for development of a multivalent PorA vaccine against N. meningitidis serogroup B. Selective removal of lipopolysaccharide (LPS) decreases toxicity, but promotes aggregation and narrows the immune response. Detergent-free OMV vaccines retain all LPS, w...
Alternative Titles
Full title
Improved OMV vaccine against Neisseria meningitidis using genetically engineered strains and a detergent-free purification process
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_wageningen_narcis_oai_library_wur_nl_wurpubs_395604
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_wageningen_narcis_oai_library_wur_nl_wurpubs_395604
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2010.04.082
