Prion disease tempo determined by host-dependent substrate reduction
Prion disease tempo determined by host-dependent substrate reduction
About this item
Full title
Author / Creator
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
The symptoms of prion infection can take years or decades to manifest following the initial exposure. Molecular markers of prion disease include accumulation of the misfolded prion protein (PrPSc), which is derived from its cellular precursor (PrPC), as well as downregulation of the PrP-like Shadoo (Sho) glycoprotein. Given the overlapping cellular...
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Full title
Prion disease tempo determined by host-dependent substrate reduction
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Record Identifier
TN_cdi_wageningen_narcis_oai_library_wur_nl_wurpubs_455309
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_wageningen_narcis_oai_library_wur_nl_wurpubs_455309
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI72241
