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Select record 21
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Comparison of irinotecan and oxaliplatin as the first-line therapies for metastatic colorectal cancer: a meta-analysis
Author / Creator:Kawai, Sadayuki ; Takeshima, Nozomi ; Hayasaka, Yu ; Notsu, Akifumi ; Yamazaki, Mutsumi ; Kawabata, Takanori ; Yamazaki, Kentaro ; Mori, Keita ; Yasui, Hirofumi
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2021-02, Vol.21 (1), p.116-11, Article 116
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Drug-Drug Interactions of Irinotecan, 5-Fluorouracil, Folinic Acid and Oxaliplatin and Its Activity in Colorectal Carcinoma Treatment
Author / Creator:Zoetemelk, Marloes ; Ramzy, George M. ; Rausch, Magdalena ; Nowak-Sliwinska, Patrycja
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-06, Vol.25 (11), p.2614
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Nanoliposomal irinotecan with fluorouracil for the treatment of advanced pancreatic cancer, a single institution experience
Author / Creator:Glassman, Danielle C. ; Palmaira, Randze L. ; Covington, Christina M. ; Desai, Avni M. ; Ku, Geoffrey Y. ; Li, Jia ; Harding, James J. ; Varghese, Anna M. ; O’Reilly, Eileen M. ; Yu, Kenneth H.
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2018-06, Vol.18 (1), p.693-693, Article 693
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Irinotecan and temozolomide in combination with dasatinib and rapamycin versus irinotecan and temozolomide for patients with relapsed or refractory neuroblastoma (RIST-rNB-2011): a multicentre, open-l...
Author / Creator:Corbacioglu, Selim, MD PhD ; Lode, Holger, MD PhD ; Ellinger, Susanne, MSc ; Zeman, Florian, MSc ; Suttorp, Meinolf, MD PhD ; Escherich, Gabriele, MD ; Bochennek, Konrad, MD ; Gruhn, Bernd, MD ; Lang, Peter, MD ; Rohde, Marius, MD ; Debatin, Klaus Michael, MD PhD ; Steinbach, Daniel, MD ; Beilken, Andreas, MD ; Ladenstein, Ruth, MD ; Spachtholz, Rainer, MSc ; Heiss, Peter, MD ; Hellwig, Dirk, MD PhD ; Tröger, Anja, MD PhD ; Koller, Michael, PhD ; Menhart, Karin, MD ; Riemenschneider, Markus J, MD ; Zoubaa, Saida, MD ; Kietz, Silke, MD ; Jakob, Marcus, MD ; Sommer, Gunhild, PhD ; Heise, Tilman, PhD ; Hundsdörfer, Patrick, MD ; Kühnle, Ingrid, MD ; Dilloo, Dagmar, MD ; Schönberger, Stefan, MD ; Schwabe, Georg, MD ; von Luettichau, Irene, MD ; Graf, Norbert, MD ; Schlegel, Paul-Gerhardt, MD ; Frühwald, Michael, MD PhD ; Jorch, Norbert, MD ; Paulussen, Michael, MD ; Schneider, Dominik T, MD ; Metzler, Markus, MD ; Leipold, Alfred, MD ; Nathrath, Michaela, MD ; Imschweiler, Thomas, MD ; Christiansen, Holger, MD ; Schmid, Irene, MD ; Crazzolara, Roman, MD ; Niktoreh, Naghmeh, MD ; Cario, Gunnar, MD ; Faber, Joerg, MD ; Demmert, Martin, MD ; Babor, Florian, MD ; Fröhlich, Birgit, MD ; Bielack, Stefan, MD ; Bernig, Toralf, MD ; Greil, Johann, MD ; Eggert, Angelika, MD PhD ; Simon, Thorsten, MD ; Foell, Juergen, MD PhD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2024-07, Vol.25 (7), p.922-932
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A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy
Author / Creator:Kaissis, Georgios ; Ziegelmayer, Sebastian ; Lohöfer, Fabian ; Steiger, Katja ; Algül, Hana ; Muckenhuber, Alexander ; Yen, Hsi-Yu ; Rummeny, Ernst ; Friess, Helmut ; Schmid, Roland ; Weichert, Wilko ; Siveke, Jens T. ; Braren, Rickmer
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-10, Vol.14 (10), p.e0218642
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Phase 2 study of irinotecan plus cetuximab rechallenge as third-line treatment in KRAS wild-type metastatic colorectal cancer: JACCRO CC-08
Author / Creator:Masuishi, Toshiki ; Tsuji, Akihito ; Kotaka, Masahito ; Nakamura, Masato ; Kochi, Mitsugu ; Takagane, Akinori ; Shimada, Ken ; Denda, Tadamichi ; Segawa, Yoshihiko ; Tanioka, Hiroaki ; Hara, Hiroki ; Sagawa, Tamotsu ; Watanabe, Takanori ; Takahashi, Takao ; Negoro, Yuji ; Manaka, Dai ; Fujita, Hideto ; Suto, Takeshi ; Takeuchi, Masahiro ; Ichikawa, Wataru ; Fujii, Masashi
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2020-11, Vol.123 (10), p.1490-1495
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Combined and targeted drugs delivery system for colorectal cancer treatment: Conatumumab decorated, reactive oxygen species sensitive irinotecan prodrug and quercetin co-loaded nanostructured lipid ca...
Author / Creator:Liu, Youqiang ; Zhang, Hongxin ; Cui, Haijing ; Zhang, Futong ; Zhao, Liyan ; Liu, Yibing ; Meng, Qingju
Publisher:England: Taylor & Francis
Journal title:Drug delivery, 2022-12, Vol.29 (1), p.342-350
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A Phase III open-label trial to evaluate efficacy and safety of CPI-613 plus modified FOLFIRINOX (mFFX) versus FOLFIRINOX (FFX) in patients with metastatic adenocarcinoma of the pancreas
Author / Creator:Philip, Philip A ; Buyse, Marc E ; Alistar, Angela T ; Lima, Caio MSPR ; Luther, Sanjeev ; Pardee, Timothy S ; Cutsem, Eric Van
Publisher:England: Future Medicine Ltd
Journal title:Future oncology (London, England), 2019-10, Vol.15 (28), p.3189-3196
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Addition of temsirolimus to chemotherapy in children, adolescents, and young adults with intermediate-risk rhabdomyosarcoma (ARST1431): a randomised, open-label, phase 3 trial from the Children's Onco...
Author / Creator:Gupta, Abha A, Prof ; Xue, Wei, PhD ; Harrison, Douglas J, MD ; Hawkins, Douglas S, Prof ; Dasgupta, Roshni, Prof ; Wolden, Suzanne, Prof ; Shulkin, Barry, MD ; Qumseya, Amira, MSc ; Routh, Jonathan C, MD ; MacDonald, Tamara, PharmD ; Feinberg, Shari, NP ; Crompton, Brian, MD ; Rudzinski, Erin R, Prof ; Arnold, Michael, MD ; Venkatramani, Raj, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2024-07, Vol.25 (7), p.912-921
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Select record 30
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An analytical “quality by design” approach in RP-HPLC method development and validation for reliable and rapid estimation of irinotecan in an injectable formulation
Author / Creator:Bhaskaran, Navya Ajitkumar ; Kumar, Lalit ; Reddy, M Sreenivasa ; Pai, Girish K
Publisher:Poland: Sciendo
Journal title:Acta Pharmaceutica, 2021-03, Vol.71 (1), p.57-79
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Select record 31
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Metformin plus lrinotecan in patients with refractory colorectal cancer: a phase 2 clinical trial
Author / Creator:Bragagnoli, Arinilda Campos ; Araujo, Raphael L. C. ; Ferraz, Mauricio Wagner ; dos Santos, Lucas Vieira ; Abdalla, Kathia Cristina ; Comar, Fabiana ; Santos, Florinda Almeida ; Oliveira, Marco Antonio ; Carvalheira, José Barreto Campello ; Cárcano, Flávio Mavigner ; da Silveira Nogueira Lima, João Paulo
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2021-03, Vol.124 (6), p.1072-1078
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A randomised phase II study of second-line XELIRI regimen versus irinotecan monotherapy in advanced biliary tract cancer patients progressed on gemcitabine and cisplatin
Author / Creator:Zheng, Yi ; Tu, Xiaoxuan ; Zhao, Peng ; Jiang, Weiqin ; Liu, Lulu ; Tong, Zhou ; Zhang, Hangyu ; Yan, Cong ; Fang, Weijia ; Wang, Weilin
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2018-08, Vol.119 (3), p.291-295
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Population Pharmacokinetics of Sacituzumab Govitecan in Patients with Metastatic Triple-Negative Breast Cancer and Other Solid Tumors
Author / Creator:Sathe, Abhishek G. ; Singh, Indrajeet ; Singh, Pratap ; Diderichsen, Paul M. ; Wang, Xiaohui ; Chang, Peter ; Taqui, Atiya ; Phan, See ; Girish, Sandhya ; Othman, Ahmed A.
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2024-05, Vol.63 (5), p.669-681
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Select record 34
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Liposomal irinotecan in metastatic pancreatic adenocarcinoma in Asian patients: Subgroup analysis of the NAPOLI‐1 study
Author / Creator:Bang, Yung‐Jue ; Li, Chung‐Pin ; Lee, Kyung‐Hun ; Chiu, Chang‐Fang ; Park, Joon Oh ; Shan, Yan‐Shen ; Kim, Jun Suk ; Chen, Jen‐Shi ; Shim, Hyun‐Jeong ; Rau, Kun‐Ming ; Choi, Hye Jin ; Oh, Do‐Youn ; Belanger, Bruce ; Chen, Li‐Tzong
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2020-02, Vol.111 (2), p.513-527
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Select record 35
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Efficacy and safety of FOLFIRINOX as salvage treatment in advanced biliary tract cancer: an open-label, single arm, phase 2 trial
Author / Creator:Belkouz, Ali ; de Vos-Geelen, Judith ; Mathôt, Ron A. A. ; Eskens, Ferry A. L. M. ; van Gulik, Thomas M. ; van Oijen, Martijn G. H. ; Punt, Cornelis J. A. ; Wilmink, Johanna W. ; Klümpen, Heinz-Josef
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2020-03, Vol.122 (5), p.634-639
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Adjuvant Gemcitabine Versus Neoadjuvant/Adjuvant FOLFIRINOX in Resectable Pancreatic Cancer: The Randomized Multicenter Phase II NEPAFOX Trial
Author / Creator:Goetze, Thorsten O. ; Reichart, Alexander ; Bankstahl, Ulli S. ; Pauligk, Claudia ; Loose, Maria ; Kraus, Thomas W. ; Elshafei, Moustafa ; Bechstein, Wolf O. ; Trojan, Jörg ; Behrend, Matthias ; Homann, Nils ; Venerito, Marino ; Bohle, Wolfram ; Varvenne, Michael ; Bolling, Claus ; Behringer, Dirk M. ; Kratz-Albers, Karsten ; Siegler, Gabriele M. ; Hozaeel, Wael ; Al-Batran, Salah-Eddin
Publisher:Cham: Springer International Publishing
Journal title:Annals of surgical oncology, 2024-06, Vol.31 (6), p.4073-4083
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Select record 37
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Tislelizumab plus cetuximab and irinotecan in refractory microsatellite stable and RAS wild-type metastatic colorectal cancer: a single-arm phase 2 study
Author / Creator:Xu, Xiaojing ; Ai, Luoyan ; Hu, Keshu ; Liang, Li ; Lv, Minzhi ; Wang, Yan ; Cui, Yuehong ; Li, Wei ; Li, Qian ; Yu, Shan ; Feng, Yi ; Liu, Qing ; Yang, Ying ; Zhang, Jiao ; Xu, Fei ; Yu, Yiyi ; Liu, Tianshu
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-08, Vol.15 (1), p.7255-13, Article 7255
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Select record 38
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Intravenous liposomal irinotecan in metastatic triple-negative breast cancer after ≥ 2 prior lines of chemotherapy: a phase Ib study
Author / Creator:Fan, Ying ; Zhang, Qingyuan ; Yan, Min ; Qu, Xiujuan ; Yin, Yongmei ; Sun, Tao ; Yang, Jin ; Wang, Ying ; Wang, Xu ; Niu, Zhaofeng ; Wang, Xinshuai ; Sun, Sanyuan ; Zhao, Weihong ; Liu, Yanping ; Niu, Miao ; Zhao, Xuemin ; Xu, Binghe
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-01, Vol.16 (1), p.3-10, Article 3
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Select record 39
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Neoadjuvant modified FOLFIRINOX followed by postoperative gemcitabine in borderline resectable pancreatic adenocarcinoma: a Phase 2 study for clinical and biomarker analysis
Author / Creator:Yoo, Changhoon ; Lee, Sang Soo ; Song, Ki Byung ; Jeong, Jae Ho ; Hyung, Jaewon ; Park, Do Hyun ; Song, Tae Jun ; Seo, Dong Wan ; Lee, Sung Koo ; Kim, Myung-Hwan ; Lee, Seung Soo ; Kim, Jin Hee ; Jin, Hyung-seung ; Park, Jin-hong ; Hwang, Dae Wook ; Lee, Jae Hoon ; Lee, Woohyung ; Chang, Heung-Moon ; Kim, Kyu-pyo ; Ryoo, Baek-Yeol ; Kim, Song Cheol
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2020-08, Vol.123 (3), p.362-368
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Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage
Author / Creator:Carotenuto, Pietro ; Amato, Francesco ; Lampis, Andrea ; Rae, Colin ; Hedayat, Somaieh ; Previdi, Maria C. ; Zito, Domenico ; Raj, Maya ; Guzzardo, Vincenza ; Sclafani, Francesco ; Lanese, Andrea ; Parisi, Claudia ; Vicentini, Caterina ; Said-Huntingford, Ian ; Hahne, Jens C. ; Hallsworth, Albert ; Kirkin, Vladimir ; Young, Kate ; Begum, Ruwaida ; Wotherspoon, Andrew ; Kouvelakis, Kyriakos ; Azevedo, Sergio Xavier ; Michalarea, Vasiliki ; Upstill-Goddard, Rosie ; Rao, Sheela ; Watkins, David ; Starling, Naureen ; Sadanandam, Anguraj ; Chang, David K. ; Biankin, Andrew V. ; Jamieson, Nigel B. ; Scarpa, Aldo ; Cunningham, David ; Chau, Ian ; Workman, Paul ; Fassan, Matteo ; Valeri, Nicola ; Braconi, Chiara
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-11, Vol.12 (1), p.6738-14, Article 6738
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Comparison of irinotecan and oxaliplatin as the first-line therapies for metastatic colorectal cancer: a meta-analysis

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Drug-Drug Interactions of Irinotecan, 5-Fluorouracil, Folinic Acid and Oxaliplatin and Its Activity in Colorectal Carcinoma Treatment

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Nanoliposomal irinotecan with fluorouracil for the treatment of advanced pancreatic cancer, a single institution experience

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Irinotecan and temozolomide in combination with dasatinib and rapamycin versus irinotecan and temozolomide for patients with relapsed or refractory neuroblastoma (RIST-rNB-2011): a multicentre, open-l...

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A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy

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Phase 2 study of irinotecan plus cetuximab rechallenge as third-line treatment in KRAS wild-type metastatic colorectal cancer: JACCRO CC-08

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Combined and targeted drugs delivery system for colorectal cancer treatment: Conatumumab decorated, reactive oxygen species sensitive irinotecan prodrug and quercetin co-loaded nanostructured lipid ca...

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A Phase III open-label trial to evaluate efficacy and safety of CPI-613 plus modified FOLFIRINOX (mFFX) versus FOLFIRINOX (FFX) in patients with metastatic adenocarcinoma of the pancreas

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Addition of temsirolimus to chemotherapy in children, adolescents, and young adults with intermediate-risk rhabdomyosarcoma (ARST1431): a randomised, open-label, phase 3 trial from the Children's Onco...

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An analytical “quality by design” approach in RP-HPLC method development and validation for reliable and rapid estimation of irinotecan in an injectable formulation

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Metformin plus lrinotecan in patients with refractory colorectal cancer: a phase 2 clinical trial

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A randomised phase II study of second-line XELIRI regimen versus irinotecan monotherapy in advanced biliary tract cancer patients progressed on gemcitabine and cisplatin

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Population Pharmacokinetics of Sacituzumab Govitecan in Patients with Metastatic Triple-Negative Breast Cancer and Other Solid Tumors

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Liposomal irinotecan in metastatic pancreatic adenocarcinoma in Asian patients: Subgroup analysis of the NAPOLI‐1 study

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Efficacy and safety of FOLFIRINOX as salvage treatment in advanced biliary tract cancer: an open-label, single arm, phase 2 trial

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Adjuvant Gemcitabine Versus Neoadjuvant/Adjuvant FOLFIRINOX in Resectable Pancreatic Cancer: The Randomized Multicenter Phase II NEPAFOX Trial

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Tislelizumab plus cetuximab and irinotecan in refractory microsatellite stable and RAS wild-type metastatic colorectal cancer: a single-arm phase 2 study

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Intravenous liposomal irinotecan in metastatic triple-negative breast cancer after ≥ 2 prior lines of chemotherapy: a phase Ib study

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Neoadjuvant modified FOLFIRINOX followed by postoperative gemcitabine in borderline resectable pancreatic adenocarcinoma: a Phase 2 study for clinical and biomarker analysis

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Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage

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