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Select record 21
ArticlesPeer ReviewedFull Text
A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen
Author / Creator:Quek, Adam J. ; Cowieson, Nathan P. ; Caradoc-Davies, Tom T. ; Conroy, Paul J. ; Whisstock, James C. ; Law, Ruby H. P.
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2023-09, Vol.24 (18), p.14258
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Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin
Author / Creator:Lukoyanova, Natalya ; Kondos, Stephanie C. ; Farabella, Irene ; Law, Ruby H. P. ; Reboul, Cyril F. ; Caradoc-Davies, Tom T. ; Spicer, Bradley A. ; Kleifeld, Oded ; Traore, Daouda A. K. ; Ekkel, Susan M. ; Voskoboinik, Ilia ; Trapani, Joseph A. ; Hatfaludi, Tamas ; Oliver, Katherine ; Hotze, Eileen M. ; Tweten, Rodney K. ; Whisstock, James C. ; Topf, Maya ; Saibil, Helen R. ; Dunstone, Michelle A.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2015-02, Vol.13 (2), p.e1002049
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GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop
Author / Creator:Fenalti, Gustavo ; Law, Ruby H P ; Buckle, Ashley M ; Langendorf, Christopher ; Tuck, Kellie ; Rosado, Carlos J ; Faux, Noel G ; Mahmood, Khalid ; Hampe, Christiane S ; Banga, J Paul ; Wilce, Matthew ; Schmidberger, Jason ; Rossjohn, Jamie ; El-Kabbani, Ossama ; Pike, Robert N ; Smith, A Ian ; Mackay, Ian R ; Rowley, Merrill J ; Whisstock, James C
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2007-04, Vol.14 (4), p.280-286
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Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin
Author / Creator:Brennan, Amelia J. ; Law, Ruby H. P. ; Conroy, Paul J. ; Noori, Tahereh ; Lukoyanova, Natalya ; Saibil, Helen ; Yagita, Hideo ; Ciccone, Annette ; Verschoor, Sandra ; Whisstock, James C. ; Trapani, Joseph A. ; Voskoboinik, Ilia
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2018-08, Vol.25 (8), p.1517-1529
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The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates
Author / Creator:Kennan, Ruth M. ; Wong, Wilson ; Dhungyel, Om P. ; Han, Xiaoyan ; Wong, David ; Parker, Dane ; Rosado, Carlos J. ; Law, Ruby H. P. ; McGowan, Sheena ; Reeve, Shane B. ; Levina, Vita ; Powers, Glenn A. ; Pike, Robert N. ; Bottomley, Stephen P. ; Smith, A. Ian ; Marsh, Ian ; Whittington, Richard J. ; Whisstock, James C. ; Porter, Corrine J. ; Rood, Julian I.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2010-11, Vol.6 (11), p.e1001210-e1001210
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An overview of the serpin superfamily
Author / Creator:Law, Ruby H P ; Zhang, Qingwei ; McGowan, Sheena ; Buckle, Ashley M ; Silverman, Gary A ; Wong, Wilson ; Rosado, Carlos J ; Langendorf, Chris G ; Pike, Rob N ; Bird, Philip I ; Whisstock, James C
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology (Online Edition), 2006-01, Vol.7 (5), p.216-1202
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The role of NINJ1 protein in programmed cellular destruction
Author / Creator:Whisstock, James C. ; Law, Ruby H. P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-06, Vol.618 (7967), p.912-914
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The X-Ray Crystal Structure of Escherichia coli Succinic Semialdehyde Dehydrogenase; Structural Insights into NADP+/Enzyme Interactions
Author / Creator:Langendorf, Christopher G. ; Key, Trevor L. G. ; Fenalti, Gustavo ; Kan, Wan-Ting ; Buckle, Ashley M. ; Caradoc-Davies, Tom ; Tuck, Kellie L. ; Law, Ruby H. P. ; Whisstock, James C.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-02, Vol.5 (2), p.e9280
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COOH-Terminal Clustering of Autoantibody and T-Cell Determinants on the Structure of GAD65 Provide Insights Into the Molecular Basis of Autoreactivity
Author / Creator:Fenalti, Gustavo ; Hampe, Christiane S. ; Arafat, Yasir ; Law, Ruby H.P. ; Banga, J. Paul ; Mackay, Ian R. ; Whisstock, James C. ; Buckle, Ashley M. ; Rowley, Merrill J.
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2008-05, Vol.57 (5), p.1293-1301
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Structure of granzyme C reveals an unusual mechanism of protease autoinhibition
Author / Creator:Kaiserman, Dion ; Buckle, Ashley M ; Van Damme, Petra ; Irving, James A ; Law, Ruby H.P ; Matthews, Antony Y ; Bashtannyk-Puhalovich, Tanya ; Langendorf, Chris ; Thompson, Philip ; Vandekerckhove, Joël ; Gevaert, Kris ; Whisstock, James C ; Bird, Phillip I
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (14), p.5587-5592
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Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma
Author / Creator:Kryza, Thomas ; Khan, Tashbib ; Puttick, Simon ; Li, Chao ; Sokolowski, Kamil A ; Tse, Brian WC ; Cuda, Tahleesa ; Lyons, Nicholas ; Gough, Madeline ; Yin, Julia ; Parkin, Ashleigh ; Deryugina, Elena I ; Quigley, James P. ; Law, Ruby H. P. ; Whisstock, James C. ; Riddell, Andrew D. ; Barbour, Andrew P. ; Wyld, David K. ; Thomas, Paul A. ; Rose, Stephen ; Snell, Cameron E. ; Pajic, Marina ; He, Yaowu ; Hooper, John D.
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2020-01, Vol.10 (9), p.4116-4133
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Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer
Author / Creator:Harrington, Brittney S. ; He, Yaowu ; Khan, Tashbib ; Puttick, Simon ; Conroy, Paul J. ; Kryza, Thomas ; Cuda, Tahleesa ; Sokolowski, Kamil A ; Tse, Brian WC ; Robbins, Katherine K. ; Arachchige, Buddhika J. ; Stehbens, Samantha J. ; Pollock, Pamela M. ; Reed, Sarah ; Weroha, S. John ; Haluska, Paul ; Salomon, Carlos ; Lourie, Rohan ; Perrin, Lewis C. ; Law, Ruby H. P. ; Whisstock, James C. ; Hooper, John D
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2020-01, Vol.10 (5), p.2095-2114
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Select record 33
ArticlesPeer ReviewedFull Text
Maspin is not required for embryonic development or tumour suppression
Author / Creator:Teoh, Sonia S. Y. ; Vieusseux, Jessica ; Prakash, Monica ; Berkowicz, Susan ; Luu, Jennii ; Bird, Catherina H. ; Law, Ruby H. P. ; Rosado, Carlos ; Price, John T. ; Whisstock, James C. ; Bird, Phillip I.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-01, Vol.5 (1), p.3164-3164, Article 3164
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The N terminus of the serpin, tengpin, functions to trap the metastable native state
Author / Creator:Zhang, Qingwei ; Buckle, Ashley M ; Law, Ruby H P ; Pearce, Mary C ; Cabrita, Lisa D ; Lloyd, Gordon J ; Irving, James A ; Smith, A Ian ; Ruzyla, Katya ; Rossjohn, Jamie ; Bottomley, Stephen P ; Whisstock, James C
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:EMBO reports, 2007-07, Vol.8 (7), p.658-663
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Select record 35
ArticlesPeer ReviewedFull Text
The role of NINJ1 protein in programmed destruction
Author / Creator:Whisstock, James C ; Law, Ruby H P
Publisher:London: Nature Publishing Group
Journal title:Nature (London), 2023-06, Vol.618 (7967), p.912-914
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Select record 36
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High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster
Author / Creator:Ellisdon, Andrew M ; Zhang, Qingwei ; Henstridge, Michelle A ; Johnson, Travis K ; Warr, Coral G ; Law, Ruby HP ; Whisstock, James C
Publisher:England: BioMed Central Ltd
Journal title:BMC structural biology, 2014-04, Vol.14 (1), p.14-14, Article 14
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Select record 37
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The X-Ray Crystal Structure of Escherichia coli Succinic Semialdehyde Dehydrogenase; Structural Insights into NADP.sup.+/Enzyme Interactions
Author / Creator:Langendorf, Christopher G ; Key, Trevor L. G ; Fenalti, Gustavo ; Kan, Wan-Ting ; Buckle, Ashley M ; Caradoc-Davies, Tom ; Tuck, Kellie L ; Law, Ruby H. P ; Whisstock, James C
Publisher:Public Library of Science
Journal title:PloS one, 2010-02, Vol.5 (2), p.e9280
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Select record 38
ArticlesPeer ReviewedFull Text
Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin: e1002049
Author / Creator:Lukoyanova, Natalya ; Kondos, Stephanie C ; Farabella, Irene ; Law, Ruby HP ; Reboul, Cyril F ; Caradoc-Davies, Tom T ; Spicer, Bradley A ; Kleifeld, Oded ; Traore, Daouda AK ; Ekkel, Susan M ; Voskoboinik, Ilia ; Trapani, Joseph A ; Hatfaludi, Tamas ; Oliver, Katherine ; Hotze, Eileen M ; Tweten, Rodney K ; Whisstock, James C ; Topf, Maya ; Saibil, Helen R ; Dunstone, Michelle A
Publisher:San Francisco: Public Library of Science
Journal title:PLoS biology, 2015-02, Vol.13 (2)
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Select record 39
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Stability of the Octameric Structure Affects Plasminogen-Binding Capacity of Streptococcal Enolase: e0121764
Author / Creator:Cork, Amanda J ; Ericsson, Daniel J ; Law, Ruby HP ; Casey, Lachlan W ; Valkov, Eugene ; Bertozzi, Carlo ; Stamp, Anna ; Jovcevski, Blagojce ; Aquilina, J Andrew ; Whisstock, James C
Journal title:PloS one, 2015-03, Vol.10 (3)
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Select record 40
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The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates: e1001210
Author / Creator:Kennan, Ruth M ; Wong, Wilson ; Dhungyel, Om P ; Han, Xiaoyan ; Wong, David ; Parker, Dane ; Rosado, Carlos J ; Law, Ruby HP ; McGowan, Sheena ; Reeve, Shane B ; Levina, Vita ; Powers, Glenn A ; Pike, Robert N ; Bottomley, Stephen P ; Smith, A Ian ; Marsh, Ian ; Whittington, Richard J ; Whisstock, James C ; Porter, Corrine J ; Rood, Julian I
Publisher:San Francisco: Public Library of Science
Journal title:PLoS pathogens, 2010-11, Vol.6 (11)
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Showing 21 to 40 of 39 results

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A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen

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Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin

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GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

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Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin

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The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates

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An overview of the serpin superfamily

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The role of NINJ1 protein in programmed cellular destruction

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The X-Ray Crystal Structure of Escherichia coli Succinic Semialdehyde Dehydrogenase; Structural Insights into NADP+/Enzyme Interactions

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COOH-Terminal Clustering of Autoantibody and T-Cell Determinants on the Structure of GAD65 Provide Insights Into the Molecular Basis of Autoreactivity

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Structure of granzyme C reveals an unusual mechanism of protease autoinhibition

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Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma

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Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer

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Maspin is not required for embryonic development or tumour suppression

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The N terminus of the serpin, tengpin, functions to trap the metastable native state

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The role of NINJ1 protein in programmed destruction

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High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster

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The X-Ray Crystal Structure of Escherichia coli Succinic Semialdehyde Dehydrogenase; Structural Insights into NADP.sup.+/Enzyme Interactions

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Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin: e1002049

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Stability of the Octameric Structure Affects Plasminogen-Binding Capacity of Streptococcal Enolase: e0121764

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The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates: e1001210

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