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Newsletter articlesFull Text
The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation
Publisher:NewsRX LLC
Journal title:Life Science Weekly, 2020, p.7109
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ArticlesFull Text
Findings on Mitochondria Reported by Investigators at University of British Columbia [The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondria! function and virulence in the pathoge...
Publisher:NewsRX LLC
Journal title:Obesity, fitness, & wellness week, 2018-09, p.1066
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ArticlesFull Text
Researchers at University of British Columbia Have Reported New Data on Pathogen Research [The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence in the pa...
Publisher:NewsRX LLC
Journal title:Obesity, fitness, & wellness week, 2018-08, p.3093
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ArticlesFull Text
Exocyst subunit Sec6 is positioned by microtubule overlaps in the moss phragmoplast prior to the arrival of cell plate membrane
Author / Creator:Tang, Han ; De Keijzer, Jeroen ; Overdijk, Elysa ; Sweep, Els ; Steentjes, Maikel ; Vermeer, Joop ; Janson, Marcel ; Ketelaar, Tijs
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2018-07
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ArticlesFull Text
Retrograde transport defects in Munc18-1 null neurons explain abnormal Golgi morphology
Author / Creator:Van Berkel, Annemiek A ; Santos, Tatiana C ; Shaweis, Hesho ; Jan Rt Van Weering ; Toonen, Ruud Fg ; Verhage, Matthijs
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-05
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ArticlesFull Text
Proteomic and biochemical comparison of the cellular interaction partners of human VPS33A and VPS33B
Author / Creator:Hunter, Morag R ; Hesketh, Geoffrey G ; Gingras, Anne-Claude ; Graham, Stephen C
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2017-12
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ArticlesFull Text
Proteomic Profiling of Mammalian COPII Vesicles
Author / Creator:Adolf, Frank ; Rhiel, Manuel ; Hessling, Bernd ; Hellwig, Andrea ; Wieland, Felix T
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2018-01
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ArticlesPeer ReviewedFull Text
SNARE zippering requires activation by SNARE-like peptides in Sec1/Munc18 proteins
Author / Creator:Yu, Haijia ; Shen, Chong ; Liu, Yinghui ; Menasche, Bridget L. ; Ouyang, Yan ; Stowell, Michael H. B. ; Shen, Jingshi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-09, Vol.115 (36), p.E8421-E8429
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ArticlesPeer ReviewedFull Text
Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins
Author / Creator:Yu, Haijia ; Rathore, Shailendra S. ; Lopez, Jamie A. ; Davis, Eric M. ; James, David E. ; Martin, Jennifer L. ; Shen, Jingshi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (35), p.E3271-E3280
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ArticlesPeer ReviewedFull Text
Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells
Author / Creator:Côte, Marjorie ; Ménager, Mickaël M. ; Burgess, Agathe ; Mahlaoui, Nizar ; Picard, Capucine ; Schaffner, Catherine ; Al-Manjomi, Fahad ; Al-Harbi, Musa ; Alangari, Abdullah ; Le Deist, Françoise ; Gennery, Andrew R. ; Prince, Nathalie ; Cariou, Astrid ; Nitschke, Patrick ; Blank, Ulrich ; El-Ghazali, Gehad ; Ménasché, Gaël ; Latour, Sylvain ; Fischer, Alain ; de Saint Basile, Geneviève
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2009-12, Vol.119 (12), p.3765-3773
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ArticlesPeer ReviewedFull Text
Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins
Author / Creator:Hu, Shu-Hong ; Latham, Catherine F ; Gee, Christine L ; James, David E ; Martin, Jennifer L
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (21), p.8773-8778
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ArticlesPeer ReviewedFull Text
De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy
Author / Creator:Saitsu, Hirotomo ; Kato, Mitsuhiro ; Mizuguchi, Takeshi ; Hamada, Keisuke ; Osaka, Hitoshi ; Tohyama, Jun ; Uruno, Katsuhisa ; Kumada, Satoko ; Nishiyama, Kiyomi ; Nishimura, Akira ; Okada, Ippei ; Yoshimura, Yukiko ; Hirai, Syu-ichi ; Kumada, Tatsuro ; Hayasaka, Kiyoshi ; Fukuda, Atsuo ; Ogata, Kazuhiro ; Matsumoto, Naomichi
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2008-06, Vol.40 (6), p.782-788
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ArticlesPeer ReviewedFull Text
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
Author / Creator:Dekker, Annelot M. ; Diekstra, Frank P. ; van der Spek, Rick A. A. ; Võsa, Urmo ; Yang, Jian ; Vajda, Alice ; Lin, Kuang ; Vrabec, Katarina ; Koritnik, Blaž ; Zidar, Janez ; de Visser, Marianne ; Leonardis, Lea ; Millecamps, Stéphanie ; Meininger, Vincent ; Mora, Jesus S. ; Colville, Shuna ; Morrison, Karen E. ; Shaw, Pamela J. ; Hardy, John ; Pittman, Alan ; Sidle, Katie ; Malaspina, Andrea ; Petri, Susanne ; Drepper, Carsten ; Meyer, Thomas ; Ophoff, Roel A. ; Staats, Kim A. ; Van Deerlin, Vivianna M. ; Trojanowski, John Q. ; Elman, Lauren ; McCluskey, Leo ; Basak, A Nazli ; Hamzeiy, Hamid ; Parman, Yesim ; Meitinger, Thomas ; Smith, Bradley N. ; Lichtner, Peter ; Radivojkov-Blagojevic, Milena ; Andres, Christian R. ; Maurel, Cindy ; Landwehrmeyer, Bernhard ; Brice, Alexis ; Payan, Christine A. M. ; Saker-Delye, Safaa ; Tittmann, Lukas ; Rietschel, Marcella ; Cichon, Sven ; Nöthen, Markus M. ; Tzourio, Christophe ; Dartigues, Jean-François ; Cereda, Cristina ; Uitterlinden, Andre G. ; Estrada, Karol ; Hofman, Albert ; Curtis, Charles ; Comi, Giacomo P. ; D'Alfonso, Sandra ; Fogh, Isabella ; Bertolin, Cinzia ; Sorarù, Gianni ; Tiloca, Cinzia ; Ratti, Antonia ; Calvo, Andrea ; Brunetti, Maura ; van Doormaal, Perry T. C. ; Arcuti, Simona ; Capozzo, Rosa ; Lunetta, Christian ; Riva, Nilo ; Filosto, Massimiliano ; Muller, Bernard ; Tazelaar, Gijs H. P. ; Zhang, Katharine ; McCann, Emily P. ; Rowe, Dominic B. ; Grosskreutz, Julian ; Ringer, Thomas ; Prell, Tino ; Stubendorff, Beatrice ; Beghi, Ettore ; Pupillo, Elisabetta ; Blokhuis, Anna M. ; Tortelli, Rosanna ; Powell, John ; Ludolph, Albert C. ; Van Damme, Philip ; Franke, Lude ; Brown, Robert H. ; Sproviero, William ; Andersen, Peter M. ; Silani, Vincenzo ; Jones, Ashley R. ; Pasterkamp, R Jeroen ; Breen, Gerome ; Al-Chalabi, Ammar ; Veldink, Jan H. ; Kenna, Kevin P. ; Harschnitz, Oliver ; Schellevis, Raymond D. ; Brands, William J.
Publisher:New York: Springer Nature
Journal title:Nature genetics, 2016-09, Vol.48 (9), p.1043-1048
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ArticlesPeer ReviewedFull Text
A34 CLINICAL AND CELLULAR STUDIES IN ALLERGIC DISEASE: Control Of Mast Cell Regulated Exocytosis By Munc18 Proteins
Author / Creator:Grebenkova, B A Gutierrez ; Chavez, M A ; Ramos, M A ; Rodarte, A I ; Petrova, Y ; Adachi, R
Publisher:New York: American Thoracic Society
Journal title:American journal of respiratory and critical care medicine, 2017-01, Vol.195
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ArticlesPeer ReviewedFull Text
Impaired cortico-striatal excitatory transmission triggers epilepsy
Author / Creator:Miyamoto, Hiroyuki ; Tatsukawa, Tetsuya ; Shimohata, Atsushi ; Yamagata, Tetsushi ; Suzuki, Toshimitsu ; Amano, Kenji ; Mazaki, Emi ; Raveau, Matthieu ; Ogiwara, Ikuo ; Oba-Asaka, Atsuko ; Hensch, Takao K. ; Itohara, Shigeyoshi ; Sakimura, Kenji ; Kobayashi, Kenta ; Kobayashi, Kazuto ; Yamakawa, Kazuhiro
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-04, Vol.10 (1), p.1917-1917, Article 1917
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ArticlesPeer ReviewedFull Text
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
Author / Creator:Zhang, Yingsha ; Pak, ChangHui ; Han, Yan ; Ahlenius, Henrik ; Zhang, Zhenjie ; Chanda, Soham ; Marro, Samuele ; Patzke, Christopher ; Acuna, Claudio ; Covy, Jason ; Xu, Wei ; Yang, Nan ; Danko, Tamas ; Chen, Lu ; Wernig, Marius ; Südhof, Thomas C.
Publisher:United States: Elsevier Inc
Journal title:Neuron (Cambridge, Mass.), 2013-06, Vol.78 (5), p.785-798
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ArticlesPeer ReviewedFull Text
Munc18-1 is crucial to overcome the inhibition of synaptic vesicle fusion by αSNAP
Author / Creator:Stepien, Karolina P. ; Prinslow, Eric A. ; Rizo, Josep
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-09, Vol.10 (1), p.4326-18, Article 4326
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ArticlesPeer ReviewedFull Text
Membrane Fusion: Grappling with SNARE and SM Proteins
Author / Creator:Südhof, Thomas C ; Rothman, James E
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2009-01, Vol.323 (5913), p.474-477
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ArticlesPeer ReviewedFull Text
Syntaxin binding mechanism and disease-causing mutations in Munc18-2
Author / Creator:Hackmann, Yvonne ; Graham, Stephen C. ; Ehl, Stephan ; Höning, Stefan ; Lehmberg, Kai ; Aricò, Maurizio ; Owen, David J. ; Griffiths, Gillian M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (47), p.E4482-E4491
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ArticlesPeer ReviewedFull Text
Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins
Author / Creator:Yu, Haijia ; Rathore, Shailendra S. ; Lopez, Jamie A. ; Davis, Eric M. ; James, David E. ; Martin, Jennifer L. ; Shen, Jingshi
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (35), p.14122-14122
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The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation

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Findings on Mitochondria Reported by Investigators at University of British Columbia [The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondria! function and virulence in the pathoge...

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Researchers at University of British Columbia Have Reported New Data on Pathogen Research [The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence in the pa...

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Exocyst subunit Sec6 is positioned by microtubule overlaps in the moss phragmoplast prior to the arrival of cell plate membrane

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Retrograde transport defects in Munc18-1 null neurons explain abnormal Golgi morphology

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Proteomic and biochemical comparison of the cellular interaction partners of human VPS33A and VPS33B

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Proteomic Profiling of Mammalian COPII Vesicles

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SNARE zippering requires activation by SNARE-like peptides in Sec1/Munc18 proteins

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Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins

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Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells

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Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins

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De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy

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Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

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A34 CLINICAL AND CELLULAR STUDIES IN ALLERGIC DISEASE: Control Of Mast Cell Regulated Exocytosis By Munc18 Proteins

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Impaired cortico-striatal excitatory transmission triggers epilepsy

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Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells

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Munc18-1 is crucial to overcome the inhibition of synaptic vesicle fusion by αSNAP

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Membrane Fusion: Grappling with SNARE and SM Proteins

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Syntaxin binding mechanism and disease-causing mutations in Munc18-2

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Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins

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