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238 results for Skin+Neoplasms+-+enzymology

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Select record 21
ArticlesPeer ReviewedFull Text
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4
Author / Creator:Prickett, Todd D ; Agrawal, Neena S ; Wei, Xiaomu ; Yates, Kristin E ; Lin, Jimmy C ; Wunderlich, John R ; Cronin, Julia C ; Cruz, Pedro ; Rosenberg, Steven A ; Samuels, Yardena
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2009-10, Vol.41 (10), p.1127-1132
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Fusion partners of NTRK3 affect subcellular localization of the fusion kinase and cytomorphology of melanocytes
Author / Creator:de la Fouchardière, Arnaud ; Tee, Meng Kian ; Peternel, Sandra ; Valdebran, Manuel ; Pissaloux, Daniel ; Tirode, Franck ; Busam, Klaus J. ; LeBoit, Philip E. ; McCalmont, Timothy H. ; Bastian, Boris C. ; Yeh, Iwei
Publisher:New York: Elsevier Inc
Journal title:Modern pathology, 2021-04, Vol.34 (4), p.735-747
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Comprehensive investigation of matrix metalloproteinases in skin cutaneous melanoma: diagnostic, prognostic, and therapeutic insights
Author / Creator:Wu, Lingxia ; Liu, Chenxiaoxiao ; Hu, Weicai
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-01, Vol.15 (1), p.2152-19, Article 2152
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Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032
Author / Creator:Rubinstein, Jill C ; Sznol, Mario ; Pavlick, Anna C ; Ariyan, Stephan ; Cheng, Elaine ; Bacchiocchi, Antonella ; Kluger, Harriet M ; Narayan, Deepak ; Halaban, Ruth
Publisher:England: BioMed Central Ltd
Journal title:Journal of translational medicine, 2010-07, Vol.8 (1), p.67-67, Article 67
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Selumetinib plus dacarbazine versus placebo plus dacarbazine as first-line treatment for BRAF-mutant metastatic melanoma: a phase 2 double-blind randomised study
Author / Creator:Robert, Caroline, Dr ; Dummer, Reinhard, Prof ; Gutzmer, Ralf, Prof ; Lorigan, Paul, MB ; Kim, Kevin B, MD ; Nyakas, Marta, MD ; Arance, Ana, MD ; Liszkay, Gabriella, Prof ; Schadendorf, Dirk, Prof ; Cantarini, Mireille, MBChB ; Spencer, Stuart, MSc ; Middleton, Mark R, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2013-07, Vol.14 (8), p.733-740
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Correlation of BRAF and NRAS mutation status with outcome, site of distant metastasis and response to chemotherapy in metastatic melanoma
Author / Creator:Carlino, M S ; Haydu, L E ; Kakavand, H ; Menzies, A M ; Hamilton, A L ; Yu, B ; Ng, C C ; Cooper, W A ; Thompson, J F ; Kefford, R F ; O'Toole, S A ; Scolyer, R A ; Long, G V
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2014-07, Vol.111 (2), p.292-299
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TERT promoter mutations are frequent in atypical fibroxanthomas and pleomorphic dermal sarcomas
Author / Creator:Griewank, Klaus G ; Schilling, Bastian ; Murali, Rajmohan ; Bielefeld, Nicola ; Schwamborn, Marion ; Sucker, Antje ; Zimmer, Lisa ; Hillen, Uwe ; Schaller, Jörg ; Brenn, Thomas ; Schadendorf, Dirk ; Mentzel, Thomas
Publisher:New York: Elsevier Inc
Journal title:Modern pathology, 2014-04, Vol.27 (4), p.502-508
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Mutations of the TERT promoter are common in basal cell carcinoma and squamous cell carcinoma
Author / Creator:Scott, Glynis A ; Laughlin, Todd S ; Rothberg, Paul G
Publisher:New York: Elsevier Inc
Journal title:Modern pathology, 2014-04, Vol.27 (4), p.516-523
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Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells
Author / Creator:Liu, Jiaqi ; Gu, Jianying ; Feng, Zihao ; Yang, Yanhong ; Zhu, Ningwen ; Lu, Weiyue ; Qi, Fazhi
Publisher:England: BioMed Central Ltd
Journal title:Journal of translational medicine, 2016-01, Vol.14 (1), p.7, Article 7
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ArticlesPeer ReviewedFull Text
Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway
Author / Creator:Sun, Xuerong ; Shi, Benyan ; Zheng, Huiling ; Ling, Min ; Yang, Jie ; Li, Xiaoyi ; Liao, Xiaoxin ; Huang, Weixing ; Zhang, Mingmeng ; Xu, Shun ; Zhu, Zhe ; Cui, Hongjing ; Liu, Xinguang
Publisher:London: Springer Nature B.V
Journal title:Cell death & disease, 2018-02, Vol.9, p.1-15
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ArticlesPeer ReviewedFull Text
Targeting PRPK and TOPK for skin cancer prevention and therapy
Author / Creator:Roh, Eunmiri ; Lee, Mee-Hyun ; Zykova, Tatyana A. ; Zhu, Feng ; Nadas, Janos ; Kim, Hong-Gyum ; Bae, Ki Beom ; Li, Yan ; Cho, Yong Yeon ; Curiel-Lewandrowski, Clara ; Einspahr, Janine ; Dickinson, Sally E. ; Bode, Ann M. ; Dong, Zigang
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2018-10, Vol.37 (42), p.5633-5647
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ArticlesPeer ReviewedFull Text
Characterisation of the cancer-associated glucocorticoid system: key role of 11β-hydroxysteroid dehydrogenase type 2
Author / Creator:Cirillo, Nicola ; Morgan, David J ; Pedicillo, Maria Carmela ; Celentano, Antonio ; Lo Muzio, Lorenzo ; McCullough, Michael J ; Prime, Stephen S
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2017-09, Vol.117 (7), p.984-993
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Select record 33
ArticlesPeer ReviewedFull Text
Suppression of the solar ultraviolet-induced skin carcinogenesis by TOPK inhibitor HI-TOPK-032
Author / Creator:Roh, Eunmiri ; Han, Yaping ; Reddy, Kanamata ; Zykova, Tatyana A. ; Lee, Mee Hyun ; Yao, Ke ; Bai, Ruihua ; Curiel-Lewandrowski, Clara ; Dong, Zigang
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-05, Vol.39 (21), p.4170-4182
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Select record 34
ArticlesPeer ReviewedFull Text
Cyclo-oxygenase-2 Plays a Critical Role in UV-induced Skin Carcinogenesis
Author / Creator:Rundhaug, Joyce E. ; Fischer, Susan M.
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Photochemistry and photobiology, 2008-03, Vol.84 (2), p.322-329
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Select record 35
ArticlesPeer ReviewedFull Text
Overexpression of Akt converts radial growth melanoma to vertical growth melanoma
Author / Creator:Govindarajan, Baskaran ; Sligh, James E. ; Vincent, Bethaney J. ; Li, Meiling ; Canter, Jeffrey A. ; Nickoloff, Brian J. ; Rodenburg, Richard J. ; Smeitink, Jan A. ; Oberley, Larry ; Zhang, Yuping ; Slingerland, Joyce ; Arnold, Rebecca S. ; Lambeth, J. David ; Cohen, Cynthia ; Hilenski, Lu ; Griendling, Kathy ; Martínez-Diez, Marta ; Cuezva, José M. ; Arbiser, Jack L.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2007-03, Vol.117 (3), p.719-729
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ArticlesPeer ReviewedFull Text
Loss of protein phosphatase 6 in mouse keratinocytes enhances K‐ras G12D ‐driven tumor promotion
Author / Creator:Kurosawa, Koreyuki ; Inoue, Yui ; Kakugawa, Yoichiro ; Yamashita, Yoji ; Kanazawa, Kosuke ; Kishimoto, Kazuhiro ; Nomura, Miyuki ; Momoi, Yuki ; Sato, Ikuro ; Chiba, Natsuko ; Suzuki, Mai ; Ogoh, Honami ; Yamada, Hidekazu ; Miura, Koh ; Watanabe, Toshio ; Tanuma, Nobuhiro ; Tachi, Masahiro ; Shima, Hiroshi
Publisher:England: John Wiley and Sons Inc
Journal title:Cancer science, 2018-07, Vol.109 (7), p.2178-2187
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Select record 37
ArticlesPeer ReviewedFull Text
Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma
Author / Creator:Mittal, Amit ; Wang, Mike ; Vidyarthi, Aurobind ; Yanez, Diana ; Pizzurro, Gabriela ; Thakral, Durga ; Tracy, Erin ; Colegio, Oscar R.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-05, Vol.11 (1), p.10731-11, Article 10731
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Select record 38
ArticlesPeer ReviewedFull Text
Role of AMPK in UVB-induced DNA damage repair and growth control
Author / Creator:Wu, C L ; Qiang, L ; Han, W ; Ming, M ; Viollet, B ; He, Y Y
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2013-05, Vol.32 (21), p.2682-2689
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Select record 39
ArticlesPeer ReviewedFull Text
Variable indoleamine 2,3‐dioxygenase expression in acral/mucosal melanoma and its possible link to immunotherapy
Author / Creator:Iga, Natsuko ; Otsuka, Atsushi ; Hirata, Masahiro ; Kataoka, Tatsuki R. ; Irie, Hiroyuki ; Nakashima, Chisa ; Matsushita, Shigeto ; Uchi, Hiroshi ; Yamamoto, Yuki ; Funakoshi, Takeru ; Fujisawa, Yasuhiro ; Yoshino, Koji ; Fujimura, Taku ; Hata, Hiroo ; Ishida, Yoshihiro ; Kabashima, Kenji
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2019-11, Vol.110 (11), p.3434-3441
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Select record 40
ArticlesPeer ReviewedFull Text
Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma
Author / Creator:Scortegagna, M ; Ruller, C ; Feng, Y ; Lazova, R ; Kluger, H ; Li, J-L ; De, S K ; Rickert, R ; Pellecchia, M ; Bosenberg, M ; Ronai, Z A
Publisher:England
Journal title:Oncogene, 2014-08, Vol.33 (34), p.4330
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Showing 21 to 40 of 238 results

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Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4

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Fusion partners of NTRK3 affect subcellular localization of the fusion kinase and cytomorphology of melanocytes

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Comprehensive investigation of matrix metalloproteinases in skin cutaneous melanoma: diagnostic, prognostic, and therapeutic insights

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Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032

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Selumetinib plus dacarbazine versus placebo plus dacarbazine as first-line treatment for BRAF-mutant metastatic melanoma: a phase 2 double-blind randomised study

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Correlation of BRAF and NRAS mutation status with outcome, site of distant metastasis and response to chemotherapy in metastatic melanoma

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TERT promoter mutations are frequent in atypical fibroxanthomas and pleomorphic dermal sarcomas

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Mutations of the TERT promoter are common in basal cell carcinoma and squamous cell carcinoma

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Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells

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Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway

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Targeting PRPK and TOPK for skin cancer prevention and therapy

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Characterisation of the cancer-associated glucocorticoid system: key role of 11β-hydroxysteroid dehydrogenase type 2

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Suppression of the solar ultraviolet-induced skin carcinogenesis by TOPK inhibitor HI-TOPK-032

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Cyclo-oxygenase-2 Plays a Critical Role in UV-induced Skin Carcinogenesis

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Overexpression of Akt converts radial growth melanoma to vertical growth melanoma

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Loss of protein phosphatase 6 in mouse keratinocytes enhances K‐ras G12D ‐driven tumor promotion

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Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma

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Role of AMPK in UVB-induced DNA damage repair and growth control

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Variable indoleamine 2,3‐dioxygenase expression in acral/mucosal melanoma and its possible link to immunotherapy

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Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma

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