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Select record 21
ArticlesPeer ReviewedFull Text
Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids
Author / Creator:Workman, Michael J. ; Troisi, Elissa ; Targan, Stephan R. ; Svendsen, Clive N. ; Barrett, Robert J.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-12, Vol.22 (1), p.288
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Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome
Author / Creator:Jacob, Noam ; Jacobs, Jonathan P. ; Kumagai, Kotaro ; Ha, Connie W. Y. ; Kanazawa, Yoshitake ; Lagishetty, Venu ; Altmayer, Katherine ; Hamill, Ariel M. ; Von Arx, Aimee ; Sartor, R. Balfour ; Devkota, Suzanne ; Braun, Jonathan ; Michelsen, Kathrin S. ; Targan, Stephan R. ; Shih, David Q.
Publisher:New York: Nature Publishing Group US
Journal title:Mucosal immunology, 2018-09, Vol.11 (5), p.1466-1476
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DEVELOPMENT OF A PERSONALIZED MODEL OF INTESTINAL FIBROSIS USING HUMAN INTESTINAL ORGANOIDS DERIVED FROM INDUCED PLURIPOTENT STEM CELLS
Author / Creator:Estrada, Hannah ; Patel, Shachi ; Rabizadeh, Shervin ; Targan, Stephan ; Barrett, Robert
Publisher:US: Oxford University Press
Journal title:Inflammatory bowel diseases, 2021-01, Vol.27 (Supplement_1), p.S35-S35
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Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD
Author / Creator:Gleeson, John P. ; Estrada, Hannah Q. ; Yamashita, Michifumi ; Svendsen, Clive N. ; Targan, Stephan R. ; Barrett, Robert J.
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2020-02, Vol.21 (4), p.1438
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Differential Levels of Tl1a Affect the Expansion and Function of Regulatory T Cells in Modulating Murine Colitis
Author / Creator:Sidhu-Varma, Maninder ; Shih, David Q. ; Targan, Stephan R.
Publisher:Oxford, UK: Oxford University Press
Journal title:Inflammatory bowel diseases, 2016-03, Vol.22 (3), p.548-559
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Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo
Author / Creator:Jacob, Noam ; Kumagai, Kotaro ; Abraham, Jay P ; Shimodaira, Yosuke ; Ye, Yuefang ; Luu, Justin ; Blackwood, Anna Y ; Castanon, Sofi L ; Stamps, Dalton T ; Thomas, Lisa S ; Gonsky, Rivkah ; Shih, David Q ; Michelsen, Kathrin S ; Targan, Stephan R
Publisher:London: Nature Publishing Group
Journal title:Scientific reports, 2020-10, Vol.10 (1)
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Epithelial endoplasmic reticulum stress orchestrates a protective IgA response
Author / Creator:Grootjans, Joep ; Krupka, Niklas ; Hosomi, Shuhei ; Matute, Juan D. ; Hanley, Thomas ; Saveljeva, Svetlana ; Gensollen, Thomas ; Heijmans, Jarom ; Li, Hai ; Limenitakis, Julien P. ; Ganal-Vonarburg, Stephanie C. ; Suo, Shengbao ; Luoma, Adrienne M. ; Shimodaira, Yosuke ; Duan, Jinzhi ; Shih, David Q. ; Conner, Margaret E. ; Glickman, Jonathan N. ; Fuhler, Gwenny M. ; Palm, Noah W. ; de Zoete, Marcel R. ; van der Woude, C. Janneke ; Yuan, Guo-Cheng ; Wucherpfennig, Kai W. ; Targan, Stephan R. ; Rosenstiel, Philip ; Flavell, Richard A. ; McCoy, Kathy D. ; Macpherson, Andrew J. ; Kaser, Arthur ; Blumberg, Richard S.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2019-03, Vol.363 (6430), p.993-998
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Bacterial flagellin is a dominant antigen in Crohn disease
Author / Creator:Lodes, Michael J. ; Cong, Yingzi ; Elson, Charles O. ; Mohamath, Raodoh ; Landers, Carol J. ; Targan, Stephan R. ; Fort, Madeline ; Hershberg, Robert M.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2004-05, Vol.113 (9), p.1296-1306
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The antimicrobial peptide cathelicidin modulates Clostridium difficile-associated colitis and toxin A-mediated enteritis in mice
Author / Creator:Hing, Tressia C ; Ho, Samantha ; Shih, David Q ; Ichikawa, Ryan ; Cheng, Michelle ; Chen, Jeremy ; Chen, Xinhua ; Law, Ivy ; Najarian, Robert ; Kelly, Ciaran P ; Gallo, Richard L ; Targan, Stephan R ; Pothoulakis, Charalabos ; Koon, Hon Wai
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2013-09, Vol.62 (9), p.1295-1305
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ArticlesPeer ReviewedFull Text
IBD-Associated TL1A Gene (TNFSF15) Haplotypes Determine Increased Expression of TL1A Protein
Author / Creator:Michelsen, Kathrin S. ; Thomas, Lisa S. ; Taylor, Kent D. ; Yu, Qi T. ; Mei, Ling ; Landers, Carol J. ; Derkowski, Carrie ; McGovern, Dermot P. B. ; Rotter, Jerome I. ; Targan, Stephan R.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-03, Vol.4 (3), p.e4719-e4719
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ArticlesPeer ReviewedFull Text
Future biologic targets for IBD: potentials and pitfalls
Author / Creator:Melmed, Gil Y. ; Targan, Stephan R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Gastroenterology & hepatology, 2010-02, Vol.7 (2), p.110-117
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Immunosuppression Impairs Response to Pneumococcal Polysaccharide Vaccination in Patients With Inflammatory Bowel Disease
Author / Creator:Melmed, Gil Y ; Agarwal, Nik ; Frenck, Robert W ; Ippoliti, Andrew F ; Ibanez, Patricio ; Papadakis, Konstantinos A ; Simpson, Peter ; Barolet-Garcia, Cristina ; Ward, Joel ; Targan, Stephan R ; Vasiliauskas, Eric A
Publisher:Basingstoke: Nature Publishing Group
Journal title:The American journal of gastroenterology, 2010-01, Vol.105 (1), p.148-154
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ArticlesPeer ReviewedFull Text
P015 Familial Prevalence of Serologic Markers of IBD in a Hispanic Cohort
Author / Creator:Eduardo, Michelen-Gómez ; Aidaliz, Llorens-Bonilla ; Krystel, Ruiz-Serrano ; Dermot, McGovern ; Stephan, Targan ; Esther, Torres
Publisher:United States: Wolters Kluwer
Journal title:The American journal of gastroenterology, 2020-12, Vol.115 (Suppl 1), p.S4-S4
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ArticlesPeer ReviewedFull Text
Genetic predictors of medically refractory ulcerative colitis
Author / Creator:Haritunians, Talin ; Taylor, Kent D. ; Targan, Stephan R. ; Dubinsky, Marla ; Ippoliti, Andrew ; Kwon, Soonil ; Guo, Xiuqing ; Melmed, Gil Y. ; Berel, Dror ; Mengesha, Emebet ; Psaty, Bruce M. ; Glazer, Nicole L. ; Vasiliauskas, Eric A. ; Rotter, Jerome I. ; Fleshner, Phillip R. ; McGovern, Dermot P.B.
Publisher:Oxford, UK: Oxford University Press
Journal title:Inflammatory bowel diseases, 2010-11, Vol.16 (11), p.1830-1840
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ArticlesPeer ReviewedFull Text
IFNG rs1861494 Polymorphism Is Associated with IBD Disease Severity and Functional Changes in Both IFNG Methylation and Protein Secretion
Author / Creator:Gonsky, Rivkah ; Deem, Richard L. ; Landers, Carol J. ; Haritunians, Talin ; Yang, Shaohong ; Targan, Stephan R.
Publisher:Oxford, UK: Oxford University Press
Journal title:Inflammatory bowel diseases, 2014-10, Vol.20 (10), p.1794-1801
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Natalizumab Induction and Maintenance Therapy for Crohn's Disease
Author / Creator:Sandborn, William J ; Colombel, Jean Frédéric ; Enns, Roberts ; Feagan, Brian G ; Hanauer, Stephen B ; Lawrance, Ian C ; Panaccione, Remo ; Sanders, Martin ; Schreiber, Stefan ; Targan, Stephan ; van Deventer, Sander ; Goldblum, Ronald ; Despain, Darrin ; Hogge, Gary S ; Rutgeerts, Paul
Publisher:Boston, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2005-11, Vol.353 (18), p.1912-1925
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ArticlesPeer ReviewedFull Text
Reliable Generation of Induced Pluripotent Stem Cells From Human Lymphoblastoid Cell Lines
Author / Creator:Barrett, Robert ; Ornelas, Loren ; Yeager, Nicole ; Mandefro, Berhan ; Sahabian, Anais ; Lenaeus, Lindsay ; Targan, Stephan R. ; Svendsen, Clive N. ; Sareen, Dhruv
Publisher:Durham, NC, USA: AlphaMed Press
Journal title:Stem cells translational medicine, 2014-12, Vol.3 (12), p.1429-1434
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Select record 38
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Patients with Inflammatory Bowel Disease Are at Risk for Vaccine-Preventable Illnesses
Author / Creator:Melmed, Gil Y. ; Ippoliti, Andrew F. ; Papadakis, Konstantinos A. ; Tran, Tram T. ; Birt, Jaime L. ; Lee, Susie K. ; Frenck, Robert W. ; Targan, Stephan R. ; Vasiliauskas, Eric A.
Publisher:Oxford: Blackwell Publishing
Journal title:The American journal of gastroenterology, 2006-08, Vol.101 (8), p.1834-1840
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Recent understanding of IBD pathogenesis: Implications for future therapies
Author / Creator:Kucharzik, Torsten ; Maaser, Christian ; Lügering, Andreas ; Kagnoff, Martin ; Mayer, Lloyd ; Targan, Stephan ; Domschke, Wolfram
Publisher:Oxford, UK: Oxford University Press
Journal title:Inflammatory bowel diseases, 2006-11, Vol.12 (11), p.1068-1083
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Select record 40
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Human Intestinal Epithelial Cells Express Interleukin-10 through Toll-Like Receptor 4-Mediated Epithelial-Macrophage Crosstalk
Author / Creator:Hyun, Jinhee ; Romero, Laura ; Riveron, Reldy ; Flores, Claudia ; Kanagavelu, Saravana ; Chung, Kristina D. ; Alonso, Ana ; Sotolongo, John ; Ruiz, Jose ; Manukyan, Armine ; Chun, Sally ; Singh, Gaurav ; Salas, Pedro ; Targan, Stephan R. ; Fukata, Masayuki
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Journal of innate immunity, 2015-01, Vol.7 (1), p.87-101
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Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids

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Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome

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DEVELOPMENT OF A PERSONALIZED MODEL OF INTESTINAL FIBROSIS USING HUMAN INTESTINAL ORGANOIDS DERIVED FROM INDUCED PLURIPOTENT STEM CELLS

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Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD

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Differential Levels of Tl1a Affect the Expansion and Function of Regulatory T Cells in Modulating Murine Colitis

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Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo

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Epithelial endoplasmic reticulum stress orchestrates a protective IgA response

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Bacterial flagellin is a dominant antigen in Crohn disease

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The antimicrobial peptide cathelicidin modulates Clostridium difficile-associated colitis and toxin A-mediated enteritis in mice

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IBD-Associated TL1A Gene (TNFSF15) Haplotypes Determine Increased Expression of TL1A Protein

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Future biologic targets for IBD: potentials and pitfalls

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Immunosuppression Impairs Response to Pneumococcal Polysaccharide Vaccination in Patients With Inflammatory Bowel Disease

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P015 Familial Prevalence of Serologic Markers of IBD in a Hispanic Cohort

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Genetic predictors of medically refractory ulcerative colitis

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IFNG rs1861494 Polymorphism Is Associated with IBD Disease Severity and Functional Changes in Both IFNG Methylation and Protein Secretion

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Natalizumab Induction and Maintenance Therapy for Crohn's Disease

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Reliable Generation of Induced Pluripotent Stem Cells From Human Lymphoblastoid Cell Lines

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Patients with Inflammatory Bowel Disease Are at Risk for Vaccine-Preventable Illnesses

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Recent understanding of IBD pathogenesis: Implications for future therapies

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Human Intestinal Epithelial Cells Express Interleukin-10 through Toll-Like Receptor 4-Mediated Epithelial-Macrophage Crosstalk

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