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129 results for Tubulin+Modulators+-+chemistry

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Select record 21
ArticlesPeer ReviewedFull Text
Two Important Anticancer Mechanisms of Natural and Synthetic Chalcones
Author / Creator:Constantinescu, Teodora ; Mihis, Alin Grig
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-09, Vol.23 (19), p.11595
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A review on synthetic chalcone derivatives as tubulin polymerisation inhibitors
Author / Creator:Liu, Wenjing ; He, Min ; Li, Yongjun ; Peng, Zhiyun ; Wang, Guangcheng
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.9-38
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Design, synthesis, and bioevaluation of 1 h -pyrrolo[3,2- c ]pyridine derivatives as colchicine-binding site inhibitors with potent anticancer activities
Author / Creator:Wang, Chao ; Zhang, Yujing ; Yang, Shanbo ; Shi, Lingyu ; Rong, Rong ; Zhang, Tingting ; Wu, Yudong ; Xing, Dongming
Publisher:England
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2024-12, Vol.39 (1), p.2302320
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Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding si...
Author / Creator:Wang, Guangcheng ; Liu, Wenjing ; Gong, Zipeng ; Huang, Yong ; Li, Yongjun ; Peng, Zhiyun
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.139-144
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Colchicine Binding Site Tubulin Inhibitors Impair Vincristine-Resistant Neuroblastoma Cell Function
Author / Creator:Reed, Cinthia N. ; Garrison, Kaylee B. ; Thammathong, Joshua ; Cinatl, Jindrich ; Michaelis, Martin ; Banerjee, Souvik ; Weissmiller, April M.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2025-05, Vol.30 (10), p.2186
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Synthesis and Study of Building Blocks with Dibenzo[b,f]oxepine: Potential Microtubule Inhibitors
Author / Creator:Tobiasz, Piotr ; Borys, Filip ; Kucharska, Marta ; Poterała, Marcin ; Krawczyk, Hanna
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-06, Vol.25 (11), p.6155
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3-aryl-4-(3,4,5-trimethoxyphenyl)pyridines inhibit tubulin polymerisation and act as anticancer agents
Author / Creator:Wang, Chao ; Zhang, Yujing ; Yang, Shanbo ; Shi, Lingyu ; Xiu, Yutao ; Wu, Yudong ; Jiang, Hongfei
Publisher:England: Taylor & Francis Ltd
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2024-12, Vol.39 (1), p.2286939
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QSAR, ADMET, molecular docking, and dynamics studies of 1,2,4-triazine-3(2H)-one derivatives as tubulin inhibitors for breast cancer therapy
Author / Creator:Moussaoui, Mohamed ; Baammi, Soukayna ; Soufi, Hatim ; Baassi, Mouna ; El Allali, Achraf ; Belghiti, M. E. ; Daoud, Rachid ; Belaaouad, Said
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-07, Vol.14 (1), p.16418-16, Article 16418
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Near-atomic cryo-EM structure of PRC1 bound to the microtubule
Author / Creator:Kellogg, Elizabeth H. ; Howes, Stuart ; Ti, Shih-Chieh ; Ramírez-Aportela, Erney ; Kapoor, Tarun M. ; Chacón, Pablo ; Nogales, Eva
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (34), p.9430-9439
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3-nitropyridine analogues as novel microtubule-targeting agents
Author / Creator:Herman, Jean ; Vanstreels, Els ; Bardiot, Dorothée ; Prota, Andrea E. ; Gaillard, Natacha ; Gao, Ling-Jie ; Vercruysse, Thomas ; Persoons, Leentje ; Daems, Tinne ; Waer, Mark ; Herdewijn, Piet ; Louat, Thierry ; Steinmetz, Michel O. ; De Jonghe, Steven ; Sprangers, Ben ; Daelemans, Dirk
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-11, Vol.19 (11), p.e0307153
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ArticlesPeer ReviewedFull Text
Hydroxyethylamine based analog targets microtubule assembly: an in silico study for anti-cancerous drug development
Author / Creator:Kumar, Pawan ; Khan, Rajni ; Singh, Basant Narain ; Kumari, Anisha ; Rai, Ankit ; Singh, Anil Kumar ; Prakash, Amresh ; Ray, Shashikant
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-12, Vol.14 (1), p.31381-12, Article 31381
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ArticlesPeer ReviewedFull Text
Systematic Studies on Anti-Cancer Evaluation of Stilbene and Dibenzo[b,f]oxepine Derivatives
Author / Creator:Borys, Filip ; Tobiasz, Piotr ; Poterała, Marcin ; Fabczak, Hanna ; Krawczyk, Hanna ; Joachimiak, Ewa
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-04, Vol.28 (8), p.3558
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Select record 33
ArticlesPeer ReviewedFull Text
Computational-Based Discovery of the Anti-Cancer Activities of Pyrrole-Based Compounds Targeting the Colchicine-Binding Site of Tubulin
Author / Creator:Boichuk, Sergei ; Syuzov, Kirill ; Bikinieva, Firuza ; Galembikova, Aigul ; Zykova, Svetlana ; Gankova, Ksenia ; Igidov, Sergei ; Igidov, Nazim
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-04, Vol.27 (9), p.2873
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Select record 34
ArticlesPeer ReviewedFull Text
The Novel Autophagy Inhibitor Alpha-Hederin Promoted Paclitaxel Cytotoxicity by Increasing Reactive Oxygen Species Accumulation in Non-Small Cell Lung Cancer Cells
Author / Creator:Zhan, Yujuan ; Wang, Kun ; Li, Qiao ; Zou, Yidan ; Chen, Bonan ; Gong, Qing ; HO, Hiuting Idy ; Yin, Ting ; Zhang, Fangyuan ; Lu, Yuhua ; Wu, Weijie ; Zhang, Yilin ; Tan, Yuhui ; Du, Biaoyan ; Liu, Xiaodong ; Xiao, Jianyong
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2018-10, Vol.19 (10), p.3221
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ArticlesPeer ReviewedFull Text
Discovery of potent tubulin inhibitors targeting the colchicine binding site via structure-based lead optimization and antitumor evaluation
Author / Creator:Liu, Wei ; He, Youyou ; Guo, Zhongjie ; Wang, Miaomiao ; Han, Xiaodong ; Jia, Hairui ; He, Jin ; Miao, Shanshan ; Wang, Shengzheng
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2155815-2155815
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Select record 36
ArticlesPeer ReviewedFull Text
Modulation Effect on Tubulin Polymerization, Cytotoxicity and Antioxidant Activity of 1H-Benzimidazole-2-Yl Hydrazones
Author / Creator:Argirova, Maria ; Guncheva, Maya ; Momekov, Georgi ; Cherneva, Emiliya ; Mihaylova, Rositsa ; Rangelov, Miroslav ; Todorova, Nadezhda ; Denev, Petko ; Anichina, Kameliya ; Mavrova, Anelia ; Yancheva, Denitsa
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-12, Vol.28 (1), p.291
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ArticlesPeer ReviewedFull Text
Identification of Potential Antitubulin Agents with Anticancer Assets from a Series of Imidazo[1,2-a]quinoxaline Derivatives: In Silico and In Vitro Approaches
Author / Creator:Goel, Kapil ; Hussain, Afzal ; Altamimi, Mohammad ; Rajput, Satyendra ; Sharma, Prince ; Kharb, Rajeev ; Mahdi, Wael ; Imam, Syed ; Alshehri, Sultan ; Alnemer, Osamah ; Chaudhary, Anu
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-01, Vol.28 (2), p.802
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Select record 38
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A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells
Author / Creator:Thomas, Elizabeth ; Gopalakrishnan, Vidya ; Hegde, Mahesh ; Kumar, Sujeet ; Karki, Subhas S. ; Raghavan, Sathees C. ; Choudhary, Bibha
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-10, Vol.6 (1), p.34653-34653, Article 34653
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Select record 39
ArticlesPeer ReviewedFull Text
Tubulin Inhibitors: A Chemoinformatic Analysis Using Cell-Based Data
Author / Creator:López-López, Edgar ; Cerda-García-Rojas, Carlos M. ; Medina-Franco, José L.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-04, Vol.26 (9), p.2483
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Select record 40
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Novel Combretastatin A-4 Analogs—Design, Synthesis, and Antiproliferative and Anti-Tubulin Activity
Author / Creator:Jędrzejczyk, Marta ; Morabito, Benedetta ; Żyżyńska-Granica, Barbara ; Struga, Marta ; Janczak, Jan ; Aminpour, Maral ; Tuszynski, Jack A. ; Huczyński, Adam
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-05, Vol.29 (10), p.2200
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Showing 21 to 40 of 129 results

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Two Important Anticancer Mechanisms of Natural and Synthetic Chalcones

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A review on synthetic chalcone derivatives as tubulin polymerisation inhibitors

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Design, synthesis, and bioevaluation of 1 h -pyrrolo[3,2- c ]pyridine derivatives as colchicine-binding site inhibitors with potent anticancer activities

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Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding si...

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Colchicine Binding Site Tubulin Inhibitors Impair Vincristine-Resistant Neuroblastoma Cell Function

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Synthesis and Study of Building Blocks with Dibenzo[b,f]oxepine: Potential Microtubule Inhibitors

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3-aryl-4-(3,4,5-trimethoxyphenyl)pyridines inhibit tubulin polymerisation and act as anticancer agents

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QSAR, ADMET, molecular docking, and dynamics studies of 1,2,4-triazine-3(2H)-one derivatives as tubulin inhibitors for breast cancer therapy

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Near-atomic cryo-EM structure of PRC1 bound to the microtubule

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3-nitropyridine analogues as novel microtubule-targeting agents

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Hydroxyethylamine based analog targets microtubule assembly: an in silico study for anti-cancerous drug development

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Systematic Studies on Anti-Cancer Evaluation of Stilbene and Dibenzo[b,f]oxepine Derivatives

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Computational-Based Discovery of the Anti-Cancer Activities of Pyrrole-Based Compounds Targeting the Colchicine-Binding Site of Tubulin

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The Novel Autophagy Inhibitor Alpha-Hederin Promoted Paclitaxel Cytotoxicity by Increasing Reactive Oxygen Species Accumulation in Non-Small Cell Lung Cancer Cells

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Discovery of potent tubulin inhibitors targeting the colchicine binding site via structure-based lead optimization and antitumor evaluation

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Modulation Effect on Tubulin Polymerization, Cytotoxicity and Antioxidant Activity of 1H-Benzimidazole-2-Yl Hydrazones

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Identification of Potential Antitubulin Agents with Anticancer Assets from a Series of Imidazo[1,2-a]quinoxaline Derivatives: In Silico and In Vitro Approaches

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A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells

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Tubulin Inhibitors: A Chemoinformatic Analysis Using Cell-Based Data

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Novel Combretastatin A-4 Analogs—Design, Synthesis, and Antiproliferative and Anti-Tubulin Activity

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