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Select record 41
ArticlesPeer ReviewedFull Text
Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
Author / Creator:Palmer, Allyson K. ; Xu, Ming ; Zhu, Yi ; Pirtskhalava, Tamar ; Weivoda, Megan M. ; Hachfeld, Christine M. ; Prata, Larissa G. ; Dijk, Theo H. ; Verkade, Esther ; Casaclang‐Verzosa, Grace ; Johnson, Kurt O. ; Cubro, Hajrunisa ; Doornebal, Ewald J. ; Ogrodnik, Mikolaj ; Jurk, Diana ; Jensen, Michael D. ; Chini, Eduardo N. ; Miller, Jordan D. ; Matveyenko, Aleksey ; Stout, Michael B. ; Schafer, Marissa J. ; White, Thomas A. ; Hickson, LaTonya J. ; Demaria, Marco ; Garovic, Vesna ; Grande, Joseph ; Arriaga, Edgar A. ; Kuipers, Folkert ; Zglinicki, Thomas ; LeBrasseur, Nathan K. ; Campisi, Judith ; Tchkonia, Tamar ; Kirkland, James L.
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2019-06, Vol.18 (3), p.e12950-n/a
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Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk
Author / Creator:Zannas, Anthony S. ; Jia, Meiwen ; Hafner, Kathrin ; Baumert, Jens ; Wiechmann, Tobias ; Pape, Julius C. ; Arloth, Janine ; Ködel, Maik ; Martinelli, Silvia ; Roitman, Maria ; Röh, Simone ; Haehle, Andreas ; Emeny, Rebecca T. ; Iurato, Stella ; Carrillo-Roa, Tania ; Lahti, Jari ; Räikkönen, Katri ; Eriksson, Johan G. ; Drake, Amanda J. ; Waldenberger, Melanie ; Wahl, Simone ; Kunze, Sonja ; Lucae, Susanne ; Bradley, Bekh ; Gieger, Christian ; Hausch, Felix ; Smith, Alicia K. ; Ressler, Kerry J. ; Müller-Myhsok, Bertram ; Ladwig, Karl-Heinz ; Rein, Theo ; Gassen, Nils C. ; Binder, Elisabeth B.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (23), p.11370-11379
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Select record 43
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Aging increases cell-to-cell transcriptional variability upon immune stimulation
Author / Creator:Martinez-Jimenez, Celia Pilar ; Eling, Nils ; Chen, Hung-Chang ; Vallejos, Catalina A. ; Kolodziejczyk, Aleksandra A. ; Connor, Frances ; Stojic, Lovorka ; Rayner, Timothy F. ; Stubbington, Michael J. T. ; Teichmann, Sarah A. ; de la Roche, Maike ; Marioni, John C. ; Odom, Duncan T.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-03, Vol.355 (6332), p.1433-1436
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An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory
Author / Creator:Lanna, Alessio ; Vaz, Bruno ; D’Ambra, Clara ; Valvo, Salvatore ; Vuotto, Claudia ; Chiurchiù, Valerio ; Devine, Oliver ; Sanchez, Massimo ; Borsellino, Giovanna ; Akbar, Arne N. ; De Bardi, Marco ; Gilroy, Derek W. ; Dustin, Michael L. ; Blumer, Brendan ; Karin, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2022-10, Vol.24 (10), p.1461-1474
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Select record 45
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Comparison of telomere length measurement methods
Author / Creator:Lai, Tsung-Po ; Wright, Woodring E. ; Shay, Jerry W.
Publisher:England: The Royal Society
Journal title:Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2018-03, Vol.373 (1741), p.20160451-20160451
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Immunosenescence: molecular mechanisms and diseases
Author / Creator:Liu, Zaoqu ; Liang, Qimeng ; Ren, Yuqing ; Guo, Chunguang ; Ge, Xiaoyong ; Wang, Libo ; Cheng, Quan ; Luo, Peng ; Zhang, Yi ; Han, Xinwei
Publisher:London: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2023-05, Vol.8 (1), p.200-200, Article 200
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Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment
Author / Creator:Jeon, Ok Hee ; Kim, Chaekyu ; Laberge, Remi-Martin ; Demaria, Marco ; Rathod, Sona ; Vasserot, Alain P ; Chung, Jae Wook ; Kim, Do Hun ; Poon, Yan ; David, Nathaniel ; Baker, Darren J ; van Deursen, Jan M ; Campisi, Judith ; Elisseeff, Jennifer H
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2017-06, Vol.23 (6), p.775-781
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Senescence-associated reprogramming promotes cancer stemness
Author / Creator:Milanovic, Maja ; Fan, Dorothy N. Y. ; Belenki, Dimitri ; Däbritz, J. Henry M. ; Zhao, Zhen ; Yu, Yong ; Dörr, Jan R. ; Dimitrova, Lora ; Lenze, Dido ; Monteiro Barbosa, Ines A. ; Mendoza-Parra, Marco A. ; Kanashova, Tamara ; Metzner, Marlen ; Pardon, Katharina ; Reimann, Maurice ; Trumpp, Andreas ; Dörken, Bernd ; Zuber, Johannes ; Gronemeyer, Hinrich ; Hummel, Michael ; Dittmar, Gunnar ; Lee, Soyoung ; Schmitt, Clemens A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-01, Vol.553 (7686), p.96-100
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Select record 49
ArticlesPeer ReviewedFull Text
Cellular senescence in osteoarthritis pathology
Author / Creator:McCulloch, Kendal ; Litherland, Gary J. ; Rai, Taranjit Singh
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2017-04, Vol.16 (2), p.210-218
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Targeting cellular senescence prevents age-related bone loss in mice
Author / Creator:Farr, Joshua N ; Xu, Ming ; Weivoda, Megan M ; Monroe, David G ; Fraser, Daniel G ; Onken, Jennifer L ; Negley, Brittany A ; Sfeir, Jad G ; Ogrodnik, Mikolaj B ; Hachfeld, Christine M ; LeBrasseur, Nathan K ; Drake, Matthew T ; Pignolo, Robert J ; Pirtskhalava, Tamar ; Tchkonia, Tamara ; Oursler, Merry Jo ; Kirkland, James L ; Khosla, Sundeep
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2017-09, Vol.23 (9), p.1072-1079
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Emerging roles of extracellular vesicles in cellular senescence and aging
Author / Creator:Takasugi, Masaki
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2018-04, Vol.17 (2), p.n/a
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The human HSP70 family of chaperones: where do we stand?
Author / Creator:Radons, Jürgen
Publisher:Dordrecht: Springer
Journal title:Cell stress & chaperones, 2016-05, Vol.21 (3), p.379-404
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The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4
Author / Creator:Kang, Chanhee ; Xu, Qikai ; Martin, Timothy D. ; Li, Mamie Z. ; Demaria, Marco ; Aron, Liviu ; Lu, Tao ; Yankner, Bruce A. ; Campisi, Judith ; Elledge, Stephen J.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-09, Vol.349 (6255), p.1503-1503
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Tissue damage and senescence provide critical signals for cellular reprogramming in vivo
Author / Creator:Mosteiro, Lluc ; Pantoja, Cristina ; Alcazar, Noelia ; Marión, Rosa M. ; Chondronasiou, Dafni ; Rovira, Miguel ; Fernandez-Marcos, Pablo J. ; Muñoz-Martin, Maribel ; Blanco-Aparicio, Carmen ; Pastor, Joaquin ; Gómez-López, Gonzalo ; De Martino, Alba ; Blasco, Maria A. ; Abad, María ; Serrano, Manuel
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-11, Vol.354 (6315), p.1020-1020
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p16(Ink4a)-induced senescence of pancreatic beta cells enhances insulin secretion
Author / Creator:Helman, Aharon ; Klochendler, Agnes ; Azazmeh, Narmen ; Gabai, Yael ; Horwitz, Elad ; Anzi, Shira ; Swisa, Avital ; Condiotti, Reba ; Granit, Roy Z ; Nevo, Yuval ; Fixler, Yaakov ; Shreibman, Dorin ; Zamir, Amit ; Tornovsky-Babeay, Sharona ; Dai, Chunhua ; Glaser, Benjamin ; Powers, Alvin C ; Shapiro, A M James ; Magnuson, Mark A ; Dor, Yuval ; Ben-Porath, Ittai
Publisher:United States
Journal title:Nature medicine, 2016-04, Vol.22 (4), p.412-420
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Inflammation and DNA damage: cause, effect or both
Author / Creator:Pezone, Antonio ; Olivieri, Fabiola ; Napoli, Maria Vittoria ; Procopio, Antonio ; Avvedimento, Enrico Vittorio ; Gabrielli, Armando
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Rheumatology, 2023-04, Vol.19 (4), p.200-211
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Stem cell aging: mechanisms, regulators and therapeutic opportunities
Author / Creator:Oh, Juhyun ; Lee, Yang David ; Wagers, Amy J
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2014-08, Vol.20 (8), p.870-880
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Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity
Author / Creator:Olova, Nelly ; Simpson, Daniel J. ; Marioni, Riccardo E. ; Chandra, Tamir
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2019-02, Vol.18 (1), p.e12877-n/a
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A human tissue‐specific transcriptomic analysis reveals a complex relationship between aging, cancer, and cellular senescence
Author / Creator:Chatsirisupachai, Kasit ; Palmer, Daniel ; Ferreira, Susana ; Magalhães, João Pedro
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2019-12, Vol.18 (6), p.e13041-n/a
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Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells
Author / Creator:Flach, Johanna ; Bakker, Sietske T. ; Mohrin, Mary ; Conroy, Pauline C. ; Pietras, Eric M. ; Reynaud, Damien ; Alvarez, Silvia ; Diolaiti, Morgan E. ; Ugarte, Fernando ; Forsberg, E. Camilla ; Le Beau, Michelle M. ; Stohr, Bradley A. ; Méndez, Juan ; Morrison, Ciaran G. ; Passegué, Emmanuelle
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-08, Vol.512 (7513), p.198-202
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Targeting senescent cells alleviates obesity‐induced metabolic dysfunction

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Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk

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Aging increases cell-to-cell transcriptional variability upon immune stimulation

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An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory

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Comparison of telomere length measurement methods

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Immunosenescence: molecular mechanisms and diseases

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Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

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Senescence-associated reprogramming promotes cancer stemness

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Cellular senescence in osteoarthritis pathology

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Targeting cellular senescence prevents age-related bone loss in mice

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Emerging roles of extracellular vesicles in cellular senescence and aging

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The human HSP70 family of chaperones: where do we stand?

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The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4

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Tissue damage and senescence provide critical signals for cellular reprogramming in vivo

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p16(Ink4a)-induced senescence of pancreatic beta cells enhances insulin secretion

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Inflammation and DNA damage: cause, effect or both

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Stem cell aging: mechanisms, regulators and therapeutic opportunities

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Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity

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A human tissue‐specific transcriptomic analysis reveals a complex relationship between aging, cancer, and cellular senescence

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Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells

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