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65 results for Cyclic+S-Oxides+-+pharmacology

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Select record 41
ArticlesPeer ReviewedFull Text
Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer
Author / Creator:Kondratyev, M ; Kreso, A ; Hallett, R M ; Girgis-Gabardo, A ; Barcelon, M E ; Ilieva, D ; Ware, C ; Majumder, P K ; Hassell, J A
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2012-01, Vol.31 (1), p.93-103
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IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentiation in newly diagnosed patients with myasthenia gravis
Author / Creator:Xu, Yanan ; Huang, Xiaoyu ; Li, Fengzhan ; Liu, Tan ; Yang, Tingting ; Chen, Fei ; Zhu, Jie ; Pan, Meng ; Zhang, Yong ; Wang, Yuzhong ; Fu, Linlin ; Xiao, Chenghua ; Geng, Deqin
Publisher:New York: Springer US
Journal title:Immunologic research, 2021-02, Vol.69 (1), p.59-70
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Mechanisms of Efficacy of the FGFR1–3 Inhibitor AZD4547 in Pediatric Solid Tumor Models
Author / Creator:Phanhthilath, Nikki ; Hakim, Sara ; Su, Catherine ; Liu, Andrea ; Subramonian, Divya ; Lesperance, Jacqueline ; Zage, Peter E.
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2020-12, Vol.38 (6), p.1677-1686
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Stattic alleviates acute hepatic damage induced by LPS/d-galactosamine in mice
Author / Creator:Li, Sijia ; Hu, Kai ; Li, Longjiang ; Shen, Yi ; Huang, Jiayi ; Tang, Li ; Zhang, Li ; Shao, Ruyue ; Lu, Han ; Yang, Yongqiang
Publisher:London, England: SAGE Publications
Journal title:Innate immunity (London, England), 2021-02, Vol.27 (2), p.201-209
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Select record 45
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Müller Cell-Derived PEDF Mediates Neuroprotection via STAT3 Activation
Author / Creator:Eichler, Wolfram ; Savković-Cvijić, Helena ; Bürger, Susanne ; Beck, Mike ; Schmidt, Manuela ; Wiedemann, Peter ; Reichenbach, Andreas ; Unterlauft, Jan Darius
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Cellular physiology and biochemistry, 2017-12, Vol.44 (4), p.1411-1424
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Bad news and good news in AD, and how to reconcile them
Author / Creator:Knopman, David S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Neurology, 2019-02, Vol.15 (2), p.61-62
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Select record 47
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Combinatory effects of vaccinia virus VG9 and the STAT3 inhibitor Stattic on cancer therapy
Author / Creator:Yang, Runlin ; Wang, Lizhen ; Sheng, Jie ; Huang, Qianhuan ; Pan, Donghui ; Xu, Yuping ; Yan, Junjie ; Wang, Xinyu ; Dong, Ziyue ; Yang, Min
Publisher:Vienna: Springer Vienna
Journal title:Archives of virology, 2019-07, Vol.164 (7), p.1805-1814
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Future Therapeutics in Alzheimer’s Disease: Development Status of BACE Inhibitors
Author / Creator:Evin, Genevieve
Publisher:Cham: Springer International Publishing
Journal title:BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy, 2016-06, Vol.30 (3), p.173-194
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Select record 49
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Signal transducer and activator of transcription 3 inhibition alleviates resistance to BRAF inhibition in anaplastic thyroid cancer
Author / Creator:Wang, Ying ; Hu, Zhigang ; Ma, Weiyuan ; Niu, Yong ; Su, Jingwei ; Zhang, Lingxiang ; Zhao, Pengxin
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2021-06, Vol.39 (3), p.764-774
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Select record 50
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STAT3 inhibitor stattic enhances radiosensitivity in esophageal squamous cell carcinoma
Author / Creator:Zhang, Qu ; Zhang, Chi ; He, Jia ; Guo, Qing ; Hu, Desheng ; Yang, Xi ; Wang, Jinfeng ; Kang, Yahui ; She, Ruifang ; Wang, Zhongming ; Li, Defan ; Huang, Guanhong ; Ma, Zhaoming ; Mao, Weidong ; Zhou, Xiaoyi ; Xiao, Chuangying ; Sun, Xinchen ; Ma, Jianxin
Publisher:Dordrecht: Springer Netherlands
Journal title:Tumor biology, 2015-03, Vol.36 (3), p.2135-2142
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In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders
Author / Creator:Rorick-Kehn, Linda M. ; Johnson, Bryan G. ; Knitowski, Karen M. ; Salhoff, Craig R. ; Witkin, Jeffrey M. ; Perry, Kenneth W. ; Griffey, Kelly I. ; Tizzano, Joseph P. ; Monn, James A. ; McKinzie, David L. ; Schoepp, Darryle D.
Publisher:Berlin: Springer
Journal title:Psychopharmacologia, 2007-07, Vol.193 (1), p.121-136
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Increased STAT1 Signaling in Endocrine-Resistant Breast Cancer
Author / Creator:Huang, Rui ; Faratian, Dana ; Sims, Andrew H. ; Wilson, Danielle ; Thomas, Jeremy S. ; Harrison, David J. ; Langdon, Simon P.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-04, Vol.9 (4), p.e94226-e94226
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Exploring the IL-21–STAT3 Axis as Therapeutic Target for Sézary Syndrome
Author / Creator:van der Fits, Leslie ; Out-Luiting, Jacoba J. ; Tensen, Cornelis P. ; Zoutman, Willem H. ; Vermeer, Maarten H.
Publisher:United States: Elsevier Inc
Journal title:Journal of investigative dermatology, 2014-10, Vol.134 (10), p.2639-2647
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Stattic Enhances Radiosensitivity and Reduces Radio-Induced Migration and Invasion in HCC Cell Lines through an Apoptosis Pathway
Author / Creator:Gong, Aihua ; Shi, Yawei ; Wang, Yan ; Zhu, Lihua ; Xu, Gang ; Wu, Chaoyang
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:BioMed research international, 2017-01, Vol.2017 (2017), p.1-9
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Select record 55
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Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition
Author / Creator:IOANNOU, NIKOLAOS ; SEDDON, ALAN M ; DALGLEISH, ANGUS ; MACKINTOSH, DAVID ; SOLCA, FLAVIO ; MODJTAHEDI, HELMOUT
Publisher:Athens: D.A. Spandidos
Journal title:International journal of oncology, 2016-03, Vol.48 (3), p.908-918
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Select record 56
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Modulation of Excitability of Stellate Neurons in the Ventral Cochlear Nucleus of Mice by ATP-Sensitive Potassium Channels
Author / Creator:Bal, Ramazan ; Ozturk, Gurkan ; Etem, Ebru Onalan ; Him, Aydin ; Cengiz, Nurattin ; Kuloglu, Tuncay ; Tuzcu, Mehmet ; Yildirim, Caner ; Tektemur, Ahmet
Publisher:New York: Springer US
Journal title:The Journal of membrane biology, 2018-02, Vol.251 (1), p.163-178
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Select record 57
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Association of Toxicity of Sorafenib and Sunitinib for Human Keratinocytes with Inhibition of Signal Transduction and Activator of Transcription 3 (STAT3)
Author / Creator:Yamamoto, Kazuhiro ; Mizumoto, Atsushi ; Nishimura, Kohji ; Uda, Atsushi ; Mukai, Akira ; Yamashita, Kazuhiko ; Kume, Manabu ; Makimoto, Hiroo ; Bito, Toshinori ; Nishigori, Chikako ; Nakagawa, Tsutomu ; Hirano, Takeshi ; Hirai, Midori
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-07, Vol.9 (7), p.e102110
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MRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma
Author / Creator:Ramakrishnan, V ; Ansell, S ; Haug, J ; Grote, D ; Kimlinger, T ; Stenson, M ; Timm, M ; Wellik, L ; Halling, T ; Rajkumar, S V ; Kumar, S
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2012-02, Vol.26 (2), p.340-348
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Select record 59
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Modulation of mGlu2 Receptors, but Not PDE10A Inhibition Normalizes Pharmacologically-Induced Deviance in Auditory Evoked Potentials and Oscillations in Conscious Rats
Author / Creator:Ahnaou, Abdallah ; Biermans, Ria ; Drinkenburg, Wilhelmus H.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-01, Vol.11 (1), p.e0147365-e0147365
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Strong therapeutic potential of γ-secretase inhibitor MRK003 for CD44-high and CD133-low glioblastoma initiating cells
Author / Creator:Tanaka, Shingo ; Nakada, Mitsutoshi ; Yamada, Daisuke ; Nakano, Ichiro ; Todo, Tomoki ; Ino, Yasushi ; Hoshii, Takayuki ; Tadokoro, Yuko ; Ohta, Kumiko ; Ali, Mohamed A. E. ; Hayashi, Yutaka ; Hamada, Jun-ichiro ; Hirao, Atsushi
Publisher:Boston: Springer US
Journal title:Journal of neuro-oncology, 2015-01, Vol.121 (2), p.239-250
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Showing 41 to 60 of 65 results

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Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer

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IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentiation in newly diagnosed patients with myasthenia gravis

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Mechanisms of Efficacy of the FGFR1–3 Inhibitor AZD4547 in Pediatric Solid Tumor Models

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Stattic alleviates acute hepatic damage induced by LPS/d-galactosamine in mice

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Müller Cell-Derived PEDF Mediates Neuroprotection via STAT3 Activation

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Bad news and good news in AD, and how to reconcile them

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Combinatory effects of vaccinia virus VG9 and the STAT3 inhibitor Stattic on cancer therapy

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Future Therapeutics in Alzheimer’s Disease: Development Status of BACE Inhibitors

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Signal transducer and activator of transcription 3 inhibition alleviates resistance to BRAF inhibition in anaplastic thyroid cancer

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STAT3 inhibitor stattic enhances radiosensitivity in esophageal squamous cell carcinoma

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In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders

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Increased STAT1 Signaling in Endocrine-Resistant Breast Cancer

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Exploring the IL-21–STAT3 Axis as Therapeutic Target for Sézary Syndrome

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Stattic Enhances Radiosensitivity and Reduces Radio-Induced Migration and Invasion in HCC Cell Lines through an Apoptosis Pathway

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Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition

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Modulation of Excitability of Stellate Neurons in the Ventral Cochlear Nucleus of Mice by ATP-Sensitive Potassium Channels

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Association of Toxicity of Sorafenib and Sunitinib for Human Keratinocytes with Inhibition of Signal Transduction and Activator of Transcription 3 (STAT3)

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MRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma

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Modulation of mGlu2 Receptors, but Not PDE10A Inhibition Normalizes Pharmacologically-Induced Deviance in Auditory Evoked Potentials and Oscillations in Conscious Rats

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Strong therapeutic potential of γ-secretase inhibitor MRK003 for CD44-high and CD133-low glioblastoma initiating cells

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