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ArticlesPeer ReviewedFull Text
Metabolic mechanisms in physiological and pathological cardiac hypertrophy: new paradigms and challenges
Author / Creator:Ritterhoff, Julia ; Tian, Rong
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews cardiology, 2023-12, Vol.20 (12), p.812-829
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The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy
Author / Creator:Ucar, Ahmet ; Gupta, Shashi K. ; Fiedler, Jan ; Erikci, Erdem ; Kardasinski, Michal ; Batkai, Sandor ; Dangwal, Seema ; Kumarswamy, Regalla ; Bang, Claudia ; Holzmann, Angelika ; Remke, Janet ; Caprio, Massimiliano ; Jentzsch, Claudia ; Engelhardt, Stefan ; Geisendorf, Sabine ; Glas, Carolina ; Hofmann, Thomas G. ; Nessling, Michelle ; Richter, Karsten ; Schiffer, Mario ; Carrier, Lucie ; Napp, L. Christian ; Bauersachs, Johann ; Chowdhury, Kamal ; Thum, Thomas
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2012-09, Vol.3 (1), p.1078-1078, Article 1078
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ArticlesPeer ReviewedFull Text
Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential
Author / Creator:Martin, Thomas G. ; Juarros, Miranda A. ; Leinwand, Leslie A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews cardiology, 2023-05, Vol.20 (5), p.347-363
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ArticlesPeer ReviewedFull Text
Molecular basis of physiological heart growth: fundamental concepts and new players
Author / Creator:Maillet, Marjorie ; van Berlo, Jop H. ; Molkentin, Jeffery D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2013-01, Vol.14 (1), p.38-48
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ArticlesPeer ReviewedFull Text
Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease
Author / Creator:Lee, Dong I. ; Zhu, Guangshuo ; Sasaki, Takashi ; Cho, Gun-Sik ; Hamdani, Nazha ; Holewinski, Ronald ; Jo, Su-Hyun ; Danner, Thomas ; Zhang, Manling ; Rainer, Peter P. ; Bedja, Djahida ; Kirk, Jonathan A. ; Ranek, Mark J. ; Dostmann, Wolfgang R. ; Kwon, Chulan ; Margulies, Kenneth B. ; Van Eyk, Jennifer E. ; Paulus, Walter J. ; Takimoto, Eiki ; Kass, David A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-03, Vol.519 (7544), p.472-476
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ArticlesPeer ReviewedFull Text
Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation
Author / Creator:Ahlberg, Gustav ; Refsgaard, Lena ; Lundegaard, Pia R. ; Andreasen, Laura ; Ranthe, Mattis F. ; Linscheid, Nora ; Nielsen, Jonas B. ; Melbye, Mads ; Haunsø, Stig ; Sajadieh, Ahmad ; Camp, Lu ; Olesen, Søren-Peter ; Rasmussen, Simon ; Lundby, Alicia ; Ellinor, Patrick T. ; Holst, Anders G. ; Svendsen, Jesper H. ; Olesen, Morten S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-10, Vol.9 (1), p.4316-11, Article 4316
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ArticlesPeer ReviewedFull Text
Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart
Author / Creator:Walejko, Jacquelyn M. ; Christopher, Bridgette A. ; Crown, Scott B. ; Zhang, Guo-Fang ; Pickar-Oliver, Adrian ; Yoneshiro, Takeshi ; Foster, Matthew W. ; Page, Stephani ; van Vliet, Stephan ; Ilkayeva, Olga ; Muehlbauer, Michael J. ; Carson, Matthew W. ; Brozinick, Joseph T. ; Hammond, Craig D. ; Gimeno, Ruth E. ; Moseley, M. Arthur ; Kajimura, Shingo ; Gersbach, Charles A. ; Newgard, Christopher B. ; White, Phillip J. ; McGarrah, Robert W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1680-1680, Article 1680
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ArticlesPeer ReviewedFull Text
Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart
Author / Creator:Xie, Jian ; Cha, Seung-Kuy ; An, Sung-Wan ; Kuro-o, Makoto ; Birnbaumer, Lutz ; Huang, Chou-Long
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2012, Vol.3 (1), p.1238-1238, Article 1238
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ArticlesPeer ReviewedFull Text
Fibroblast growth factor 21 protects against cardiac hypertrophy in mice
Author / Creator:Planavila, A. ; Redondo, I. ; Hondares, E. ; Vinciguerra, M. ; Munts, C. ; Iglesias, R. ; Gabrielli, L. A. ; Sitges, M. ; Giralt, M. ; van Bilsen, M. ; Villarroya, F.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2013-06, Vol.4 (1), p.2019-2019, Article 2019
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ArticlesPeer ReviewedFull Text
Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3
Author / Creator:Pillai, Vinodkumar B. ; Samant, Sadhana ; Sundaresan, Nagalingam R. ; Raghuraman, Hariharasundaram ; Kim, Gene ; Bonner, Michael Y. ; Arbiser, Jack L. ; Walker, Douglas I. ; Jones, Dean P. ; Gius, David ; Gupta, Mahesh P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-04, Vol.6 (1), p.6656-6656, Article 6656
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ArticlesPeer ReviewedFull Text
The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun
Author / Creator:Sundaresan, Nagalingam R ; Vasudevan, Prabhakaran ; Zhong, Lei ; Kim, Gene ; Samant, Sadhana ; Parekh, Vishwas ; Pillai, Vinodkumar B ; Ravindra, P V ; Gupta, Madhu ; Jeevanandam, Valluvan ; Cunningham, John M ; Deng, Chu-Xia ; Lombard, David B ; Mostoslavsky, Raul ; Gupta, Mahesh P
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2012-11, Vol.18 (11), p.1643-1650
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ArticlesPeer ReviewedFull Text
Microtubules orchestrate local translation to enable cardiac growth
Author / Creator:Scarborough, Emily A. ; Uchida, Keita ; Vogel, Maria ; Erlitzki, Noa ; Iyer, Meghana ; Phyo, Sai Aung ; Bogush, Alexey ; Kehat, Izhak ; Prosser, Benjamin L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1547-1547, Article 1547
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ArticlesPeer ReviewedFull Text
Correction to: Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice
Author / Creator:Deng, Ya-Wen ; Liu, Fei ; Li, Zhi-Tong ; Gao, Jing-Han ; Zhao, Yong ; Yang, Xiao-Lei ; Xia, Yun-Long
Publisher:New York: Elsevier Inc
Journal title:Laboratory investigation, 2022-10, Vol.102 (10), p.1163-1165
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ArticlesPeer ReviewedFull Text
The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling
Author / Creator:Ji, Yan-Xiao ; Zhang, Peng ; Zhang, Xiao-Jing ; Zhao, Yi-Chao ; Deng, Ke-Qiong ; Jiang, Xi ; Wang, Pi-Xiao ; Huang, Zan ; Li, Hongliang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-06, Vol.7 (1), p.11267-11267, Article 11267
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ArticlesPeer ReviewedFull Text
PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress
Author / Creator:Ranek, Mark J. ; Kokkonen-Simon, Kristen M. ; Chen, Anna ; Dunkerly-Eyring, Brittany L. ; Vera, Miguel Pinilla ; Oeing, Christian U. ; Patel, Chirag H. ; Nakamura, Taishi ; Zhu, Guangshuo ; Bedja, Djahida ; Sasaki, Masayuki ; Holewinski, Ronald J. ; Van Eyk, Jennifer E. ; Powell, Jonathan D. ; Lee, Dong Ik ; Kass, David A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-02, Vol.566 (7743), p.264-269
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ArticlesPeer ReviewedFull Text
Structural basis of agonist specificity of α1A-adrenergic receptor
Author / Creator:Su, Minfei ; Wang, Jinan ; Xiang, Guoqing ; Do, Hung Nguyen ; Levitz, Joshua ; Miao, Yinglong ; Huang, Xin-Yun
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-08, Vol.14 (1), p.4819-12, Article 4819
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ArticlesPeer ReviewedFull Text
Myricitrin Alleviates Oxidative Stress-induced Inflammation and Apoptosis and Protects Mice against Diabetic Cardiomyopathy
Author / Creator:Zhang, Bin ; Shen, Qiang ; Chen, Yaping ; Pan, Ruile ; Kuang, Shihuan ; Liu, Guiyan ; Sun, Guibo ; Sun, Xiaobo
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-03, Vol.7 (1), p.44239-16, Article 44239
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ArticlesPeer ReviewedFull Text
The KLF7/PFKL/ACADL axis modulates cardiac metabolic remodelling during cardiac hypertrophy in male mice
Author / Creator:Wang, Cao ; Qiao, Shupei ; Zhao, Yufang ; Tian, Hui ; Yan, Wei ; Hou, Xiaolu ; Wang, Ruiqi ; Zhang, Bosong ; Yang, Chaofan ; Zhu, Fuxing ; Jiao, Yanwen ; Jin, Jiaming ; Chen, Yue ; Tian, Weiming
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-02, Vol.14 (1), p.959-959, Article 959
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ArticlesPeer ReviewedFull Text
Long non-coding RNAs in cardiac hypertrophy and heart failure: functions, mechanisms and clinical prospects
Author / Creator:Mably, John D. ; Wang, Da-Zhi
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews cardiology, 2024-05, Vol.21 (5), p.326-345
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Cardiac specific PRMT1 ablation causes heart failure through CaMKII dysregulation
Author / Creator:Pyun, Jung-Hoon ; Kim, Hyun-Ji ; Jeong, Myong-Ho ; Ahn, Byeong-Yun ; Vuong, Tuan Anh ; Lee, Dong I. ; Choi, Seri ; Koo, Seung-Hoi ; Cho, Hana ; Kang, Jong-Sun
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-11, Vol.9 (1), p.5107-15, Article 5107
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Metabolic mechanisms in physiological and pathological cardiac hypertrophy: new paradigms and challenges

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The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy

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Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential

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Molecular basis of physiological heart growth: fundamental concepts and new players

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Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease

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Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation

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Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart

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Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart

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Fibroblast growth factor 21 protects against cardiac hypertrophy in mice

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Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

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The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

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Microtubules orchestrate local translation to enable cardiac growth

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Correction to: Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice

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The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling

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PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress

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Structural basis of agonist specificity of α1A-adrenergic receptor

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Myricitrin Alleviates Oxidative Stress-induced Inflammation and Apoptosis and Protects Mice against Diabetic Cardiomyopathy

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The KLF7/PFKL/ACADL axis modulates cardiac metabolic remodelling during cardiac hypertrophy in male mice

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Long non-coding RNAs in cardiac hypertrophy and heart failure: functions, mechanisms and clinical prospects

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Cardiac specific PRMT1 ablation causes heart failure through CaMKII dysregulation

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