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ArticlesPeer ReviewedFull Text
Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury
Author / Creator:Lin, Feiyan ; Chen, Wenyi ; Zhou, Jiahang ; Zhu, Jiaqi ; Yao, Qigu ; Feng, Bing ; Feng, Xudong ; Shi, Xiaowei ; Pan, Qiaoling ; Yu, Jiong ; Li, Lanjuan ; Cao, Hongcui
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2022-03, Vol.13 (3), p.271-271, Article 271
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ArticlesPeer ReviewedFull Text
Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity
Author / Creator:Janas, Maja M ; Schlegel, Mark K ; Harbison, Carole E ; Yilmaz, Vedat O ; Jiang, Yongfeng ; Parmar, Rubina ; Zlatev, Ivan ; Castoreno, Adam ; Xu, Huilei ; Shulga-Morskaya, Svetlana ; Rajeev, Kallanthottathil G ; Manoharan, Muthiah ; Keirstead, Natalie D ; Maier, Martin A ; Jadhav, Vasant
Publisher:London: Nature Publishing Group
Journal title:Nature communications, 2018-02, Vol.9, p.1-10
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ArticlesPeer ReviewedFull Text
Hepatotoxicity of immune checkpoint inhibitors: a histology study of seven cases in comparison with autoimmune hepatitis and idiosyncratic drug-induced liver injury
Author / Creator:Zen, Yoh ; Yeh, Matthew M.
Publisher:New York: Elsevier Inc
Journal title:Modern pathology, 2018-06, Vol.31 (6), p.965-973
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ArticlesPeer ReviewedFull Text
Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure
Author / Creator:Yamada Naoya ; Karasawa Tadayoshi ; Kimura Hiroaki ; Watanabe, Sachiko ; Komada Takanori ; Kamata Ryo ; Sampilvanjil Ariunaa ; Ito Junya ; Nakagawa Kiyotaka ; Kuwata, Hiroshi ; Hara Shuntaro ; Mizuta Koichi ; Sakuma Yasunaru ; Sata Naohiro ; Takahashi, Masafumi
Publisher:London: Springer Nature B.V
Journal title:Cell death & disease, 2020-02, Vol.11 (2)
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Human biomimetic liver microphysiology systems in drug development and precision medicine
Author / Creator:Gough, Albert ; Soto-Gutierrez, Alejandro ; Vernetti, Lawrence ; Ebrahimkhani, Mo R. ; Stern, Andrew M. ; Taylor, D. Lansing
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Gastroenterology & hepatology, 2021-04, Vol.18 (4), p.252-268
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Successful elimination of bilirubin in critically ill patients with acute liver dysfunction using a cytokine adsorber and albumin dialysis: a pilot study
Author / Creator:Scharf, Christina ; Liebchen, Uwe ; Paal, Michael ; Becker-Pennrich, Andrea ; Irlbeck, Michael ; Zoller, Michael ; Schroeder, Ines
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-05, Vol.11 (1), p.10190-10190, Article 10190
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Regulating Nrf2-GPx4 axis by bicyclol can prevent ferroptosis in carbon tetrachloride-induced acute liver injury in mice
Author / Creator:Zhao, Tianming ; Yu, Zihan ; Zhou, Lei ; Wang, Xiaoyu ; Hui, Yangyang ; Mao, Lihong ; Fan, Xiaofei ; Wang, Bangmao ; Zhao, Xingliang ; Sun, Chao
Publisher:New York: Springer Nature B.V
Journal title:Cell death discovery, 2022-09, Vol.8 (1)
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Nobiletin ameliorates hepatic ischemia and reperfusion injury through the activation of SIRT-1/FOXO3a-mediated autophagy and mitochondrial biogenesis
Author / Creator:Dusabimana, Theodomir ; Kim, So Ra ; Kim, Hye Jung ; Park, Sang Won ; Kim, Hwajin
Publisher:London: Nature Publishing Group UK
Journal title:Experimental and Molecular Medicine, 2019, 51(0), , pp.1-16
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Critical role of caveolin-1 in aflatoxin B1-induced hepatotoxicity via the regulation of oxidation and autophagy
Author / Creator:Xu Qingqiang ; Shi Wenwen ; Pan, Lv ; Meng Wenqi ; Mao Guanchao ; Gong Chuchu ; Chen, Yongchun ; Youheng, Wei ; He, Xiaowen ; Zhao, Jie ; Han, Hua ; Sun Mingxue ; Xiao, Kai
Publisher:London: Springer Nature B.V
Journal title:Cell death & disease, 2020-01, Vol.11 (1)
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Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury
Author / Creator:Vliegenthart, A. D. B. ; Shaffer, J. M. ; Clarke, J. I. ; Peeters, L. E. J. ; Caporali, A. ; Bateman, D. N. ; Wood, D. M. ; Dargan, P. I. ; Craig, D. G. ; Moore, J. K. ; Thompson, A. I. ; Henderson, N. C. ; Webb, D. J. ; Sharkey, J. ; Antoine, D. J. ; Park, B. K. ; Bailey, M. A. ; Lader, E. ; Simpson, K. J. ; Dear, J. W.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-10, Vol.5 (1), p.15501, Article 15501
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ArticlesPeer ReviewedFull Text
MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity
Author / Creator:Gill, Pritmohinder ; Bhattacharyya, Sudeepa ; McCullough, Sandra ; Letzig, Lynda ; Mishra, Prasun J. ; Luo, Chunqiao ; Dweep, Harsh ; James, Laura
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-09, Vol.7 (1), p.12331-11, Article 12331
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ArticlesPeer ReviewedFull Text
Histone deacetylase 2 regulates ULK1 mediated pyroptosis during acute liver failure by the K68 acetylation site
Author / Creator:Wang, Yao ; Chen, Qian ; Jiao Fangzhou ; Shi Chunxia ; Pei Maohua ; Wang, Luwen ; Gong Zuojiong
Publisher:London: Springer Nature B.V
Journal title:Cell death & disease, 2021-01, Vol.12 (1)
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Selectively targeting the AdipoR2-CaM-CaMKII-NOS3 axis by SCM-198 as a rapid-acting therapy for advanced acute liver failure
Author / Creator:Wang, Rui ; Chen, Youwei ; Han, Jiazhen ; Ye, Huikang ; Yang, Huiran ; Li, Qianyan ; He, Yizhen ; Ma, Boyu ; Zhang, Junjie ; Ge, Yanli ; Wang, Zhe ; Sun, Bo ; Liu, Huahua ; Cheng, Liming ; Wang, Zhirong ; Lin, Gufa
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-12, Vol.15 (1), p.10690-22, Article 10690
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The liver in itai-itai disease (chronic cadmium poisoning): pathological features and metallothionein expression
Author / Creator:Baba, Hayato ; Tsuneyama, Koichi ; Yazaki, Megumi ; Nagata, Kohei ; Minamisaka, Takashi ; Tsuda, Tatsuhiro ; Nomoto, Kazuhiro ; Hayashi, Shinichi ; Miwa, Shigeharu ; Nakajima, Takahiko ; Nakanishi, Yuko ; Aoshima, Keiko ; Imura, Johji
Publisher:New York: Nature Publishing Group US
Journal title:Modern pathology, 2013-09, Vol.26 (9), p.1228-1234
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ArticlesPeer ReviewedFull Text
Transient growth factor expression via mRNA in lipid nanoparticles promotes hepatocyte cell therapy in mice
Author / Creator:Smith, Anna R. ; Rizvi, Fatima ; Everton, Elissa ; Adeagbo, Anisah ; Wu, Susan ; Tam, Ying ; Muramatsu, Hiromi ; Pardi, Norbert ; Weissman, Drew ; Gouon-Evans, Valerie
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-06, Vol.15 (1), p.5010-12, Article 5010
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The effect of Alnus incana (L.) Moench extracts in ameliorating iron overload-induced hepatotoxicity in male albino rats
Author / Creator:Abo-Elghiet, Fatma ; Mohamed, Shaza A. ; Yasin, Noha A. E. ; Temraz, Abeer ; El-Tantawy, Walid Hamdy ; Ahmed, Samah Fathy
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-05, Vol.13 (1), p.7635-7635, Article 7635
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Mesenchymal stem cells ameliorate lipid metabolism through reducing mitochondrial damage of hepatocytes in the treatment of post-hepatectomy liver failure
Author / Creator:Jing-lin, Wang ; Hao-ran, Ding ; Chen-yan, Pan ; Xiao-lei, Shi ; Hao-zhen, Ren
Publisher:London: Springer Nature B.V
Journal title:Cell death & disease, 2021-01, Vol.12 (1)
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ArticlesPeer ReviewedFull Text
Shenfu injection alleviates lipopolysaccharide-induced liver injury in septic mice
Author / Creator:Lu, Bai-Tao ; Wang, Ya-Jun ; Wang, Lei ; Wu, Di ; Lin, Yi-Lu ; Xu, Jia-Xi ; Zhang, Jia-Ning ; Liu, Bo-Wen ; Liu, Hui-Ying ; Meng, Huan ; Gao, Yang ; Wang, Hong-Liang ; Kang, Kai
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-04, Vol.15 (1), p.14004-14, Article 14004
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ArticlesPeer ReviewedFull Text
Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co-therapy
Author / Creator:Li, Feng ; Lu, Jie ; Cheng, Jie ; Wang, Laiyou ; Matsubara, Tsutomu ; Csanaky, Iván L ; Klaassen, Curtis D ; Gonzalez, Frank J ; Ma, Xiaochao
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2013-04, Vol.19 (4), p.418-420
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Evaluation of tolvaptan-associated hepatic disorder using different national pharmacovigilance databases
Author / Creator:Uno, Takaya ; Hosomi, Kouichi ; Yokoyama, Satoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-10, Vol.14 (1), p.25943-10, Article 25943
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Showing 1 to 20 of 71 results

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Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury

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Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity

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Hepatotoxicity of immune checkpoint inhibitors: a histology study of seven cases in comparison with autoimmune hepatitis and idiosyncratic drug-induced liver injury

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Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure

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Human biomimetic liver microphysiology systems in drug development and precision medicine

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Successful elimination of bilirubin in critically ill patients with acute liver dysfunction using a cytokine adsorber and albumin dialysis: a pilot study

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Regulating Nrf2-GPx4 axis by bicyclol can prevent ferroptosis in carbon tetrachloride-induced acute liver injury in mice

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Nobiletin ameliorates hepatic ischemia and reperfusion injury through the activation of SIRT-1/FOXO3a-mediated autophagy and mitochondrial biogenesis

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Critical role of caveolin-1 in aflatoxin B1-induced hepatotoxicity via the regulation of oxidation and autophagy

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Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury

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MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity

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Histone deacetylase 2 regulates ULK1 mediated pyroptosis during acute liver failure by the K68 acetylation site

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Selectively targeting the AdipoR2-CaM-CaMKII-NOS3 axis by SCM-198 as a rapid-acting therapy for advanced acute liver failure

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The liver in itai-itai disease (chronic cadmium poisoning): pathological features and metallothionein expression

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Transient growth factor expression via mRNA in lipid nanoparticles promotes hepatocyte cell therapy in mice

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The effect of Alnus incana (L.) Moench extracts in ameliorating iron overload-induced hepatotoxicity in male albino rats

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Mesenchymal stem cells ameliorate lipid metabolism through reducing mitochondrial damage of hepatocytes in the treatment of post-hepatectomy liver failure

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Shenfu injection alleviates lipopolysaccharide-induced liver injury in septic mice

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Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co-therapy

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Evaluation of tolvaptan-associated hepatic disorder using different national pharmacovigilance databases

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