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ArticlesPeer ReviewedFull Text
Generation of App knock-in mice reveals deletion mutations protective against Alzheimer’s disease-like pathology
Author / Creator:Nagata, Kenichi ; Takahashi, Mika ; Matsuba, Yukio ; Okuyama-Uchimura, Fumi ; Sato, Kaori ; Hashimoto, Shoko ; Saito, Takashi ; Saido, Takaomi C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-05, Vol.9 (1), p.1800-7, Article 1800
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ArticlesPeer ReviewedFull Text
Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1
Author / Creator:Johnson, Erik C B ; Ho, Kaitlyn ; Yu, Gui-Qiu ; Das, Melanie ; Sanchez, Pascal E ; Djukic, Biljana ; Lopez, Isabel ; Yu, Xinxing ; Gill, Michael ; Zhang, Weiping ; Paz, Jeanne T ; Palop, Jorge J ; Mucke, Lennart
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2020-09, Vol.15 (1), p.53-53, Article 53
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APP Knock-In Mice Produce E22P-Aβ Exhibiting an Alzheimer’s Disease-like Phenotype with Dysregulation of Hypoxia-Inducible Factor Expression
Author / Creator:Maki, Takahito ; Sawahata, Masahito ; Akutsu, Ichiro ; Amaike, Shohei ; Hiramatsu, Genki ; Uta, Daisuke ; Izuo, Naotaka ; Shimizu, Takahiko ; Irie, Kazuhiro ; Kume, Toshiaki
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2022-11, Vol.23 (21), p.13259
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The senile plaque: Morphological differences in APP knock‐in mice brains by fixatives
Author / Creator:Yoshimura, Rikuya ; Miyasaka, Tomohiro ; Funamoto, Satoru ; Saito, Takashi ; Saido, Takaomi C. ; Ikegawa, Masaya ; Kakuda, Nobuto
Publisher:United States: John Wiley & Sons, Inc
Journal title:Brain and behavior, 2023-04, Vol.13 (4), p.e2953-n/a
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Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice
Author / Creator:Wieg, Laura ; Ciola, Jason C ; Wasén, Caroline C ; Gaba, Fidelia ; Colletti, Brianna R ; Schroeder, Maren K ; Hinshaw, Robert G ; Ekwudo, Millicent N ; Holtzman, David M ; Saito, Takashi ; Sasaguri, Hiroki ; Saido, Takaomi C ; Cox, Laura M ; Lemere, Cynthia A
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-09, Vol.25 (17), p.9379
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Autophagy Impairment in App Knock-in Alzheimer’s Model Mice
Author / Creator:Jiang, Richeng ; Shimozawa, Makoto ; Mayer, Johanna ; Tambaro, Simone ; Kumar, Rakesh ; Abelein, Axel ; Winblad, Bengt ; Bogdanovic, Nenad ; Nilsson, Per
Publisher:Lausanne: Frontiers Research Foundation
Journal title:Frontiers in aging neuroscience, 2022-05
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The Expression of the Endocannabinoid Receptors CB2 and GPR55 is Highly Increased during the Progression of Alzheimer’s Disease in AppNL-G-F Knock-In Mice
Author / Creator:Medina-Vera, Dina ; Zhao, Hongjing ; Bereczki, Erika ; Rosell-Valle, Cristina ; Shimozawa, Makoto ; Chen, Gefei ; de Fonseca, Fernando Rodríguez de ; Nilsson, Per ; Tambaro, Simone
Publisher:Basel: MDPI AG
Journal title:Biology (Basel, Switzerland), 2023-05, Vol.12 (6), p.805
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ArticlesPeer ReviewedFull Text
Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
Author / Creator:Jiang, Richeng ; Smailovic, Una ; Haytural, Hazal ; Tijms, Betty M. ; Li, Hao ; Haret, Robert Mihai ; Shevchenko, Ganna ; Chen, Gefei ; Abelein, Axel ; Gobom, Johan ; Frykman, Susanne ; Sekiguchi, Misaki ; Fujioka, Ryo ; Watamura, Naoto ; Sasaguri, Hiroki ; Nyström, Sofie ; Hammarström, Per ; Saido, Takaomi C. ; Jelic, Vesna ; Syvänen, Stina ; Zetterberg, Henrik ; Winblad, Bengt ; Bergquist, Jonas ; Visser, Pieter Jelle ; Nilsson, Per
Publisher:London: BioMed Central
Journal title:Acta neuropathologica communications, 2022, Vol.10 (1), p.1-96, Article 96
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ArticlesPeer ReviewedFull Text
Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and human proteomic studies
Author / Creator:Delvenne, Aurore ; Vandendriessche, Charysse ; Gobom, Johan ; Burgelman, Marlies ; Dujardin, Pieter ; De Nolf, Clint ; Tijms, Betty M ; Teunissen, Charlotte E ; Schindler, Suzanne E ; Verhey, Frans ; Ramakers, Inez ; Martinez-Lage, Pablo ; Tainta, Mikel ; Vandenberghe, Rik ; Schaeverbeke, Jolien ; Engelborghs, Sebastiaan ; De Roeck, Ellen ; Popp, Julius ; Peyratout, Gwendoline ; Tsolaki, Magda ; Freund-Levi, Yvonne ; Lovestone, Simon ; Streffer, Johannes ; Bertram, Lars ; Blennow, Kaj ; Zetterberg, Henrik ; Visser, Pieter Jelle ; Vandenbroucke, Roosmarijn E ; Vos, Stephanie J B
Publisher:England: BioMed Central Ltd
Journal title:Fluids and barriers of the CNS, 2024-07, Vol.21 (1), p.58-17, Article 58
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Newsletter articlesFull Text
Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice (Updated June 14, 2024)
Publisher:NewsRX LLC
Journal title:Health & Medicine Week, 2024, p.770
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ReportsFull Text
Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice
Publisher:NewsRX LLC
Journal title:Health & Medicine Week, 2024, p.770
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ReportsFull Text
Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice
Publisher:NewsRX LLC
Journal title:Health & Medicine Week, 2024, p.770
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ArticlesFull Text
Studies from Toyama University Describe New Findings in Alzheimer Disease (App Knock-in Mice Produce E22p-a Beta Exhibiting an Alzheimer's Disease-like Phenotype With Dysregulation of Hypoxia-inducibl...
Publisher:NewsRX LLC
Journal title:Obesity, fitness, & wellness week, 2022-12, p.6706
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Newsletter articlesFull Text
Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice
Publisher:NewsRX LLC
Journal title:Life Science Weekly, 2023, p.525
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ReportsFull Text
Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice
Publisher:NewsRX LLC
Journal title:Life Science Weekly, 2023, p.525
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ReportsFull Text
Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice
Publisher:NewsRX LLC
Journal title:Life Science Weekly, 2023, p.525
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ArticlesPeer ReviewedFull Text
The two faces of synaptic failure in App NL-G-F knock-in mice
Author / Creator:Latif-Hernandez, Amira ; Sabanov, Victor ; Ahmed, Tariq ; Craessaerts, Katleen ; Saito, Takashi ; Saido, Takaomi ; Balschun, Detlef
Publisher:England: BMC
Journal title:Alzheimer's research & therapy, 2020-08, Vol.12 (1), p.100-15
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Newsletter articlesFull Text
Data on Alzheimer Disease Described by Researchers at Southern Illinois University (Sexual Dimorphism, Altered Hippocampal Glutamatergic Neurotransmission, and Cognitive Impairment In App Knock-in Mic...
Publisher:NewsRX LLC
Journal title:Health & Medicine Week, 2025, p.1478
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ArticlesFull Text
Levetiracetam treatment normalizes levels of the presynaptic endocytosis machinery and restores non-amyloidogenic APP processing in App knock-in mice
Author / Creator:Rao, Nalini R ; Savas, Jeffrey N
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-02
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ArticlesFull Text
Studies from University of Tsukuba Update Current Data on Alzheimer Disease (Progressive Changes In Sleep and Its Relations To Amyloid-beta Distribution and Learning In Single App Knock-in Mice)
Publisher:NewsRX LLC
Journal title:Obesity, fitness, & wellness week, 2020-10, p.7330
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Generation of App knock-in mice reveals deletion mutations protective against Alzheimer’s disease-like pathology

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Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1

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APP Knock-In Mice Produce E22P-Aβ Exhibiting an Alzheimer’s Disease-like Phenotype with Dysregulation of Hypoxia-Inducible Factor Expression

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The senile plaque: Morphological differences in APP knock‐in mice brains by fixatives

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Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice

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Autophagy Impairment in App Knock-in Alzheimer’s Model Mice

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The Expression of the Endocannabinoid Receptors CB2 and GPR55 is Highly Increased during the Progression of Alzheimer’s Disease in AppNL-G-F Knock-In Mice

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Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis

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Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and human proteomic studies

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Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice (Updated June 14, 2024)

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Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice

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Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice

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Studies from Toyama University Describe New Findings in Alzheimer Disease (App Knock-in Mice Produce E22p-a Beta Exhibiting an Alzheimer's Disease-like Phenotype With Dysregulation of Hypoxia-inducibl...

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Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice

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Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice

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Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice

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The two faces of synaptic failure in App NL-G-F knock-in mice

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Data on Alzheimer Disease Described by Researchers at Southern Illinois University (Sexual Dimorphism, Altered Hippocampal Glutamatergic Neurotransmission, and Cognitive Impairment In App Knock-in Mic...

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Levetiracetam treatment normalizes levels of the presynaptic endocytosis machinery and restores non-amyloidogenic APP processing in App knock-in mice

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Studies from University of Tsukuba Update Current Data on Alzheimer Disease (Progressive Changes In Sleep and Its Relations To Amyloid-beta Distribution and Learning In Single App Knock-in Mice)

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