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ArticlesPeer ReviewedFull Text
High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial
Author / Creator:Boeree, Martin J, PhD ; Heinrich, Norbert, MD ; Aarnoutse, Rob, PhD ; Diacon, Andreas H, PhD ; Dawson, Rodney, PhD ; Rehal, Sunita, MSc ; Kibiki, Gibson S, Prof ; Churchyard, Gavin, Prof ; Sanne, Ian, FRCP ; Ntinginya, Nyanda E, MD ; Minja, Lilian T, MD ; Hunt, Robert D, BSc ; Charalambous, Salome, PhD ; Hanekom, Madeleine, PhD ; Semvua, Hadija H, PhD ; Mpagama, Stellah G, PhD ; Manyama, Christina, MD ; Mtafya, Bariki, MSc ; Reither, Klaus, MD ; Wallis, Robert S, Prof ; Venter, Amour, NatDipMicr ; Narunsky, Kim, MD ; Mekota, Anka, PhD ; Henne, Sonja, MSc ; Colbers, Angela, PhD ; van Balen, Georgette Plemper, PhD ; Gillespie, Stephen H, Prof ; Phillips, Patrick P J, PhD ; Hoelscher, Michael, Prof
Publisher:United States: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2017, Vol.17 (1), p.39-49
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Points to consider for the treatment of immune-mediated inflammatory diseases with Janus kinase inhibitors: a consensus statement
Author / Creator:Nash, Peter ; Kerschbaumer, Andreas ; Dörner, Thomas ; Dougados, Maxime ; Fleischmann, Roy M ; Geissler, Klaus ; McInnes, Iain ; Pope, Janet E ; van der Heijde, Désirée ; Stoffer-Marx, Michaela ; Takeuchi, Tsutomu ; Trauner, Michael ; Winthrop, Kevin L ; de Wit, Maarten ; Aletaha, Daniel ; Baraliakos, Xenofon ; Boehncke, Wolf-Henning ; Emery, Paul ; Isaacs, John D ; Kremer, Joel ; Lee, Eun Bong ; Maksymowych, Walter P ; Voshaar, Marieke ; Tam, Lai-Shan ; Tanaka, Yoshiya ; van den Bosch, Filip ; Westhovens, René ; Xavier, Ricardo ; Smolen, Josef S
Publisher:England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2021-01, Vol.80 (1), p.71-87
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Mechanically induced chemiluminescence from polymers incorporating a 1,2-dioxetane unit in the main chain
Author / Creator:Chen, Yulan ; Spiering, A. J. H. ; Karthikeyan, S. ; Peters, Gerrit W. M. ; Meijer, E. W. ; Sijbesma, Rint P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature chemistry, 2012-07, Vol.4 (7), p.559-562
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Saxagliptin and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus
Author / Creator:Scirica, Benjamin M ; Bhatt, Deepak L ; Braunwald, Eugene ; Steg, P. Gabriel ; Davidson, Jaime ; Hirshberg, Boaz ; Ohman, Peter ; Frederich, Robert ; Wiviott, Stephen D ; Hoffman, Elaine B ; Cavender, Matthew A ; Udell, Jacob A ; Desai, Nihar R ; Mosenzon, Ofri ; McGuire, Darren K ; Ray, Kausik K ; Leiter, Lawrence A ; Raz, Itamar
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2013-10, Vol.369 (14), p.1317-1326
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Efficacy and safety of peficitinib (ASP015K) in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a phase III randomised, double-blind, placebo-controlled trial...
Author / Creator:Takeuchi, Tsutomu ; Tanaka, Yoshiya ; Tanaka, Sakae ; Kawakami, Atsushi ; Iwasaki, Manabu ; Katayama, Kou ; Rokuda, Mitsuhiro ; Izutsu, Hiroyuki ; Ushijima, Satoshi ; Kaneko, Yuichiro ; Shiomi, Teruaki ; Yamada, Emi ; van der Heijde, Désirée
Publisher:England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2019-10, Vol.78 (10), p.1305-1319
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Malaria biology and disease pathogenesis: insights for new treatments
Author / Creator:Miller, Louis H ; Ackerman, Hans C ; Su, Xin-zhuan ; Wellems, Thomas E
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2013-02, Vol.19 (2), p.156-167
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Efficacy and safety of the oral Janus kinase inhibitor peficitinib (ASP015K) monotherapy in patients with moderate to severe rheumatoid arthritis in Japan: a 12-week, randomised, double-blind, placebo...
Author / Creator:Takeuchi, Tsutomu ; Tanaka, Yoshiya ; Iwasaki, Manabu ; Ishikura, Hiroaki ; Saeki, Satoshi ; Kaneko, Yuichiro
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2016-06, Vol.75 (6), p.1057-1064
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Efficacy and safety of peficitinib (ASP015K) in patients with rheumatoid arthritis and an inadequate response to conventional DMARDs: a randomised, double-blind, placebo-controlled phase III trial (RA...
Author / Creator:Tanaka, Yoshiya ; Takeuchi, Tsutomu ; Tanaka, Sakae ; Kawakami, Atsushi ; Iwasaki, Manabu ; Song, Yeong Wook ; Chen, Yi-Hsing ; Wei, James Cheng-Chung ; Lee, Sang-Heon ; Rokuda, Mitsuhiro ; Izutsu, Hiroyuki ; Ushijima, Satoshi ; Kaneko, Yuichiro ; Akazawa, Rio ; Shiomi, Teruaki ; Yamada, Emi
Publisher:England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2019-10, Vol.78 (10), p.1320-1332
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Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial
Author / Creator:Phyo, Aung Pyae, MD ; Jittamala, Podjanee, MD ; Nosten, François H, Prof ; Pukrittayakamee, Sasithon, Prof ; Imwong, Mallika, PhD ; White, Nicholas J, Prof ; Duparc, Stephan, MD ; Macintyre, Fiona, PhD ; Baker, Mark, PhD ; Möhrle, Jörg J, Dr
Publisher:United States: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2016-01, Vol.16 (1), p.61-69
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Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection
Author / Creator:Côté, Marceline ; Misasi, John ; Ren, Tao ; Bruchez, Anna ; Lee, Kyungae ; Filone, Claire Marie ; Hensley, Lisa ; Li, Qi ; Ory, Daniel ; Chandran, Kartik ; Cunningham, James
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-09, Vol.477 (7364), p.344-348
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Unusual architecture of the p7 channel from hepatitis C virus
Author / Creator:OuYang, Bo ; Xie, Shiqi ; Berardi, Marcelo J. ; Zhao, Xinhao ; Dev, Jyoti ; Yu, Wenjing ; Sun, Bing ; Chou, James J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-06, Vol.498 (7455), p.521-525
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A controlled human malaria infection model enabling evaluation of transmission-blocking interventions
Author / Creator:Collins, Katharine A. ; Wang, Claire Y.T. ; Adams, Matthew ; Mitchell, Hayley ; Rampton, Melanie ; Elliott, Suzanne ; Reuling, Isaie J. ; Bousema, Teun ; Sauerwein, Robert ; Chalon, Stephan ; Möhrle, Jörg J. ; McCarthy, James S.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-04, Vol.128 (4), p.1551-1562
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SGLT-2 Inhibition with Dapagliflozin Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Cardiomyopathy in Mice with Type 2 Diabetes. Further Augmentation o...
Author / Creator:Ye, Yumei ; Bajaj, Mandeep ; Yang, Hsiu-Chiung ; Perez-Polo, Jose R. ; Birnbaum, Yochai
Publisher:New York: Springer US
Journal title:Cardiovascular drugs and therapy, 2017-04, Vol.31 (2), p.119-132
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Peficitinib: First Global Approval
Author / Creator:Markham, Anthony ; Keam, Susan J.
Publisher:Cham: Springer International Publishing
Journal title:Drugs (New York, N.Y.), 2019-06, Vol.79 (8), p.887-891
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Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane
Author / Creator:Grzegorzewicz, Anna E ; Pham, Ha ; Gundi, Vijay A K B ; Scherman, Michael S ; North, Elton J ; Hess, Tamara ; Jones, Victoria ; Gruppo, Veronica ; Born, Sarah E M ; Korduláková, Jana ; Chavadi, Sivagami Sundaram ; Morisseau, Christophe ; Lenaerts, Anne J ; Lee, Richard E ; McNeil, Michael R ; Jackson, Mary
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2012-02, Vol.8 (4), p.334-341
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Safety and Efficacy of an Oral Inhibitor of the Purinergic Receptor P2X7 in Adult Patients with Moderately to Severely Active Crohnʼs Disease: A Randomized Placebo-controlled, Double-blind, Phase IIa...
Author / Creator:Eser, Alexander ; Colombel, Jean-Frederic ; Rutgeerts, Paul ; Vermeire, Severine ; Vogelsang, Harald ; Braddock, Martin ; Persson, Tore ; Reinisch, Walter
Publisher:England: Oxford University Press
Journal title:Inflammatory bowel diseases, 2015-10, Vol.21 (10), p.1-2253
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Reduction of Oxidative Stress and Inflammation by Blunting Daily Acute Glucose Fluctuations in Patients With Type 2 Diabetes: Role of dipeptidyl peptidase-IV inhibition
Author / Creator:ROSARIA RIZZO, Maria ; BARBIERI, Michelangela ; MARFELLA, Raffaele ; PAOLISSO, Giuseppe
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes care, 2012-10, Vol.35 (10), p.2076-2082
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Structural modulation of the gut microbiota and the relationship with body weight: compared evaluation of liraglutide and saxagliptin treatment
Author / Creator:Wang, Lin ; Li, Peicheng ; Tang, Zhaosheng ; Yan, Xinfeng ; Feng, Bo
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-09, Vol.6 (1), p.33251-33251, Article 33251
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Reversible synaptic adaptations in a subpopulation of murine hippocampal neurons following early-life seizures
Author / Creator:Xing, Bo ; Barbour, Aaron J. ; Vithayathil, Joseph ; Li, Xiaofan ; Dutko, Sierra ; Fawcett-Patel, Jessica ; Lancaster, Eunjoo ; Talos, Delia M. ; Jensen, Frances E.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2024-03, Vol.134 (5), p.1-16
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DPP-4 inhibitors: impact on glycemic control and cardiovascular risk factors
Author / Creator:Dicker, Dror
Publisher:United States: American Diabetes Association
Journal title:Diabetes care, 2011-05, Vol.34 Suppl 2 (5), p.S276-S278
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High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial

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Points to consider for the treatment of immune-mediated inflammatory diseases with Janus kinase inhibitors: a consensus statement

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Mechanically induced chemiluminescence from polymers incorporating a 1,2-dioxetane unit in the main chain

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Saxagliptin and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus

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Efficacy and safety of peficitinib (ASP015K) in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a phase III randomised, double-blind, placebo-controlled trial...

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Malaria biology and disease pathogenesis: insights for new treatments

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Efficacy and safety of the oral Janus kinase inhibitor peficitinib (ASP015K) monotherapy in patients with moderate to severe rheumatoid arthritis in Japan: a 12-week, randomised, double-blind, placebo...

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Efficacy and safety of peficitinib (ASP015K) in patients with rheumatoid arthritis and an inadequate response to conventional DMARDs: a randomised, double-blind, placebo-controlled phase III trial (RA...

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Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial

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Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

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Unusual architecture of the p7 channel from hepatitis C virus

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A controlled human malaria infection model enabling evaluation of transmission-blocking interventions

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SGLT-2 Inhibition with Dapagliflozin Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Cardiomyopathy in Mice with Type 2 Diabetes. Further Augmentation o...

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Peficitinib: First Global Approval

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Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

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Safety and Efficacy of an Oral Inhibitor of the Purinergic Receptor P2X7 in Adult Patients with Moderately to Severely Active Crohnʼs Disease: A Randomized Placebo-controlled, Double-blind, Phase IIa...

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Reduction of Oxidative Stress and Inflammation by Blunting Daily Acute Glucose Fluctuations in Patients With Type 2 Diabetes: Role of dipeptidyl peptidase-IV inhibition

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Structural modulation of the gut microbiota and the relationship with body weight: compared evaluation of liraglutide and saxagliptin treatment

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Reversible synaptic adaptations in a subpopulation of murine hippocampal neurons following early-life seizures

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DPP-4 inhibitors: impact on glycemic control and cardiovascular risk factors

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