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17 results for Adenosine+Monophosphate+-+pharmacokinetics

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Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2
Author / Creator:Williamson, Brandi N. ; Feldmann, Friederike ; Schwarz, Benjamin ; Meade-White, Kimberly ; Porter, Danielle P. ; Schulz, Jonathan ; van Doremalen, Neeltje ; Leighton, Ian ; Yinda, Claude Kwe ; Pérez-Pérez, Lizzette ; Okumura, Atsushi ; Lovaglio, Jamie ; Hanley, Patrick W. ; Saturday, Greg ; Bosio, Catharine M. ; Anzick, Sarah ; Barbian, Kent ; Cihlar, Tomas ; Martens, Craig ; Scott, Dana P. ; Munster, Vincent J. ; de Wit, Emmie
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-09, Vol.585 (7824), p.273-276
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Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19
Author / Creator:Boras, Britton ; Jones, Rhys M. ; Anson, Brandon J. ; Arenson, Dan ; Aschenbrenner, Lisa ; Bakowski, Malina A. ; Beutler, Nathan ; Binder, Joseph ; Chen, Emily ; Eng, Heather ; Hammond, Holly ; Hammond, Jennifer ; Haupt, Robert E. ; Hoffman, Robert ; Kadar, Eugene P. ; Kania, Rob ; Kimoto, Emi ; Kirkpatrick, Melanie G. ; Lanyon, Lorraine ; Lendy, Emma K. ; Lillis, Jonathan R. ; Logue, James ; Luthra, Suman A. ; Ma, Chunlong ; Mason, Stephen W. ; McGrath, Marisa E. ; Noell, Stephen ; Obach, R. Scott ; O’ Brien, Matthew N. ; O’Connor, Rebecca ; Ogilvie, Kevin ; Owen, Dafydd ; Pettersson, Martin ; Reese, Matthew R. ; Rogers, Thomas F. ; Rosales, Romel ; Rossulek, Michelle I. ; Sathish, Jean G. ; Shirai, Norimitsu ; Steppan, Claire ; Ticehurst, Martyn ; Updyke, Lawrence W. ; Weston, Stuart ; Zhu, Yuao ; White, Kris M. ; García-Sastre, Adolfo ; Wang, Jun ; Chatterjee, Arnab K. ; Mesecar, Andrew D. ; Frieman, Matthew B. ; Anderson, Annaliesa S. ; Allerton, Charlotte
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-10, Vol.12 (1), p.6055-17, Article 6055
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Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor
Author / Creator:Humeniuk, Rita ; Mathias, Anita ; Kirby, Brian J. ; Lutz, Justin D. ; Cao, Huyen ; Osinusi, Anu ; Babusis, Darius ; Porter, Danielle ; Wei, Xuelian ; Ling, John ; Reddy, Y. Sunila ; German, Polina
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2021-05, Vol.60 (5), p.569-583
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Remdesivir for severe acute respiratory syndrome coronavirus 2 causing COVID-19: An evaluation of the evidence
Author / Creator:Cao, Yu-chen ; Deng, Qi-xin ; Dai, Shi-xue
Publisher:Netherlands: Elsevier Ltd
Journal title:Travel medicine and infectious disease, 2020-05, Vol.35, p.101647-101647, Article 101647
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Safety, Tolerability, and Pharmacokinetics of Remdesivir, An Antiviral for Treatment of COVID‐19, in Healthy Subjects
Author / Creator:Humeniuk, Rita ; Mathias, Anita ; Cao, Huyen ; Osinusi, Anu ; Shen, Gong ; Chng, Estelle ; Ling, John ; Vu, Amanda ; German, Polina
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2020-09, Vol.13 (5), p.896-906
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Ecofriendly spectrophotometric methods for simultaneous determination of remdesivir and moxifloxacin hydrochloride as co administered drugs in corona virus treatment
Author / Creator:Madbouly, Eman A. ; El-Shanawani, Abdalla A. ; El-adl, Sobhy M. ; Abdelkhalek, Ahmed S.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-01, Vol.15 (1), p.1721-16, Article 1721
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An in vitro study for reducing the cytotoxicity and dose dumping risk of remdesivir via entrapment in nanostructured lipid carriers
Author / Creator:Amiri, Fatemeh ; Ziaei Chamgordani, Sepideh ; Ghourchian, Hedayatollah
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-08, Vol.14 (1), p.19360-14, Article 19360
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A Review on Remdesivir: A Possible Promising Agent for the Treatment of COVID-19
Author / Creator:Hashemian, Seyed MohammadReza ; Farhadi, Tayebeh ; Velayati, Ali Akbar
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Drug design, development and therapy, 2020-01, Vol.14, p.3215-3222
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Pharmacodynamic effects of cangrelor and clopidogrel: the platelet function substudy from the cangrelor versus standard therapy to achieve optimal management of platelet inhibition (CHAMPION) trials
Author / Creator:Angiolillo, Dominick J. ; Schneider, David J. ; Bhatt, Deepak L. ; French, William J. ; Price, Matthew J. ; Saucedo, Jorge F. ; Shaburishvili, Tamaz ; Huber, Kurt ; Prats, Jayne ; Liu, Tiepu ; Harrington, Robert A. ; Becker, Richard C.
Publisher:Boston: Springer US
Journal title:Journal of thrombosis and thrombolysis, 2012-07, Vol.34 (1), p.44-55
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Synthesis of Nucleoside-like Molecules from a Pyrolysis Product of Cellulose and Their Computational Prediction as Potential SARS-CoV-2 RNA-Dependent RNA Polymerase Inhibitors
Author / Creator:Defant, Andrea ; Dosi, Federico ; Innocenti, Nicole ; Mancini, Ines
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-01, Vol.23 (1), p.518
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Pharmacokinetics of SARS‐CoV‐2 RNA Polymerase Inhibitor Remdesivir in Participants With Moderate and Severe Hepatic Impairment
Author / Creator:Regan, Sean ; Humeniuk, Rita ; Caro, Luzelena ; Abdelghany, Mazin ; Davies, Santosh ; Baysa, Amarylliz ; Shen, Gong ; Hyland, Robert H. ; Kim, Aryun
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2025-02, Vol.18 (2), p.e70159-n/a
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A mechanism‐based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID‐19 treatment in humans
Author / Creator:Hanafin, Patrick O. ; Jermain, Brian ; Hickey, Anthony J. ; Kabanov, Alexander V. ; Kashuba, Angela DM ; Sheahan, Timothy P. ; Rao, Gauri G.
Publisher:United States: John Wiley & Sons, Inc
Journal title:CPT: pharmacometrics and systems pharmacology, 2021-02, Vol.10 (2), p.89-99
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Population pharmacokinetic modeling of GS‐441524, the active metabolite of remdesivir, in Japanese COVID‐19 patients with renal dysfunction
Author / Creator:Sukeishi, Asami ; Itohara, Kotaro ; Yonezawa, Atsushi ; Sato, Yuki ; Matsumura, Katsuyuki ; Katada, Yoshiki ; Nakagawa, Takayuki ; Hamada, Satoshi ; Tanabe, Naoya ; Imoto, Eishi ; Kai, Shinichi ; Hirai, Toyohiro ; Yanagita, Motoko ; Ohtsuru, Shigeru ; Terada, Tomohiro ; Ito, Isao
Publisher:United States: John Wiley & Sons, Inc
Journal title:CPT: pharmacometrics and systems pharmacology, 2022-01, Vol.11 (1), p.94-103
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Hemoadsorption eliminates remdesivir from the circulation: Implications for the treatment of COVID‐19
Author / Creator:Biever, Paul ; Staudacher, Dawid L. ; Sommer, Michaela J. ; Triebel, Hannah ; Neukamm, Merja A. ; Bode, Christoph ; Supady, Alexander ; Lother, Achim
Publisher:United States: John Wiley & Sons, Inc
Journal title:Pharmacology research & perspectives, 2021-04, Vol.9 (2), p.e00743-n/a
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A Novel Adenosine Precursor 2′,3′-Cyclic Adenosine Monophosphate Inhibits Formation of Post-surgical Adhesions
Author / Creator:Forman, Mervyn B. ; Gillespie, Delbert G. ; Cheng, Dongmei ; Jackson, Edwin K.
Publisher:Boston: Springer US
Journal title:Digestive diseases and sciences, 2014-09, Vol.59 (9), p.2118-2125
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Synthesis and Biodistribution of [11C]Adenosine 5′-Monophosphate ([11C]AMP)
Author / Creator:Mathews, William B. ; Nakamoto, Yuji ; Abraham, Edward H. ; Scheffel, Ursula ; Hilton, John ; Ravert, Hayden T. ; Tatsumi, Mitsuaki ; Rauseo, Paige A. ; Traughber, Bryan J. ; Salikhova, Anna Y. ; Dannals, Robert F. ; Wahl, Richard L.
Publisher:United States: Springer Nature B.V
Journal title:Molecular imaging and biology, 2005-05, Vol.7 (3), p.203-208
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The Expression of hCG Receptor mRNA in Four Human Ovarian Cancer Cell Lines Varies Considerably under Different Experimental Conditions
Author / Creator:Steinmeyer, Christoph ; Berkholz, Alexander ; Gebauer, Gerhard ; Jäger, Wolfram
Publisher:Basel, Switzerland: Karger
Journal title:Tumor biology, 2003-01, Vol.24 (1), p.13-22
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Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

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Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19

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Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor

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Remdesivir for severe acute respiratory syndrome coronavirus 2 causing COVID-19: An evaluation of the evidence

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Safety, Tolerability, and Pharmacokinetics of Remdesivir, An Antiviral for Treatment of COVID‐19, in Healthy Subjects

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Ecofriendly spectrophotometric methods for simultaneous determination of remdesivir and moxifloxacin hydrochloride as co administered drugs in corona virus treatment

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An in vitro study for reducing the cytotoxicity and dose dumping risk of remdesivir via entrapment in nanostructured lipid carriers

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A Review on Remdesivir: A Possible Promising Agent for the Treatment of COVID-19

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Pharmacodynamic effects of cangrelor and clopidogrel: the platelet function substudy from the cangrelor versus standard therapy to achieve optimal management of platelet inhibition (CHAMPION) trials

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Synthesis of Nucleoside-like Molecules from a Pyrolysis Product of Cellulose and Their Computational Prediction as Potential SARS-CoV-2 RNA-Dependent RNA Polymerase Inhibitors

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Pharmacokinetics of SARS‐CoV‐2 RNA Polymerase Inhibitor Remdesivir in Participants With Moderate and Severe Hepatic Impairment

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A mechanism‐based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID‐19 treatment in humans

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Population pharmacokinetic modeling of GS‐441524, the active metabolite of remdesivir, in Japanese COVID‐19 patients with renal dysfunction

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Hemoadsorption eliminates remdesivir from the circulation: Implications for the treatment of COVID‐19

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A Novel Adenosine Precursor 2′,3′-Cyclic Adenosine Monophosphate Inhibits Formation of Post-surgical Adhesions

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Synthesis and Biodistribution of [11C]Adenosine 5′-Monophosphate ([11C]AMP)

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The Expression of hCG Receptor mRNA in Four Human Ovarian Cancer Cell Lines Varies Considerably under Different Experimental Conditions

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