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ArticlesPeer ReviewedFull Text
Leveraging external data in the design and analysis of clinical trials in neuro-oncology
Author / Creator:Rahman, Rifaquat, MD ; Ventz, Steffen, PhD ; McDunn, Jon, PhD ; Louv, Bill, PhD ; Reyes-Rivera, Irmarie, PhD ; Polley, Mei-Yin C, PhD ; Merchant, Fahar, PhD ; Abrey, Lauren E, MD ; Allen, Joshua E, PhD ; Aguilar, Laura K, MD ; Aguilar-Cordova, Estuardo, MD ; Arons, David, JD ; Tanner, Kirk, PhD ; Bagley, Stephen, MD ; Khasraw, Mustafa, MD ; Cloughesy, Timothy, Prof ; Wen, Patrick Y, Prof ; Alexander, Brian M, MD ; Trippa, Lorenzo, PhD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2021-10, Vol.22 (10), p.e456-e465
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Gene-mediated cytotoxic immunotherapy as adjuvant to surgery or chemoradiation for pancreatic adenocarcinoma
Author / Creator:Aguilar, Laura K. ; Shirley, Lawrence A. ; Chung, Vincent M. ; Marsh, Christopher L. ; Walker, Jon ; Coyle, Walter ; Marx, Howard ; Bekaii-Saab, Tanios ; Lesinski, Gregory B. ; Swanson, Benjamin ; Sanchez, Daniel ; Manzanera, Andrea G. ; Aguilar-Cordova, Estuardo ; Bloomston, Mark
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2015-06, Vol.64 (6), p.727-736
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468 Enhancers and repressors of immunotherapy: translational perspectives on gene-mediated cytotoxic immunotherapy in glioblastoma
Author / Creator:Lawler, Sean ; Koch, Marilin ; Zdioruk, Mikolay ; Aguilar-Cordova, Estuardo ; Aguilar, Laura ; Guzik, Brian ; Tabatabai, Ghazaleh ; Nowicki, Michal ; Antonio Chiocca, E
Publisher:London: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A498-A498
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395 Detection of viral antigen and immune activation after intra-tumor injection of CAN-3110 (ICP-34.5 expressing HSV-1 oncolytic virus) in patients with recurrent high-grade glioma
Author / Creator:Barone, Francesca ; Lawler, Sean ; Aguilar, Laura ; Dwyer, Jessica ; Guzik, Brian ; Soloman, Isaac ; Nakashima, Hiroshi ; Triggs, Daniel ; Zhang, Abigail Tianai ; Zeng, Yu ; Woods, Jared ; Grant, James ; Reardon, David ; Wen, Patrick ; Lee, Eudocia Quant ; Ligon, Keith ; Pisano, William ; Rodig, Scott ; Suva, Mario ; Wucherpfennig, Kai ; Marx, Sascha ; Gritsch, Simon ; Mathewson, Nathan ; Severgnini, Mariano ; Giobbie-Hurder, Anita ; Krisky, David ; Aguilar-Cordova, Estuardo ; Tak, Paul ; Antonio Chiocca, E
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A427-A427
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Therapeutic Endoscopic Ultrasonography : Intratumoral Injection for Pancreatic Adenocarcinoma
Author / Creator:Bloomston, P. Mark ; Aguilar, Laura K. ; Aguilar-Cordova, Estuardo ; Walker, Jon P. ; Shirley, Lawrence A.
Publisher:Cairo, Egypt: Hindawi Puplishing Corporation
Journal title:Gastroenterology research and practice, 2013-01, Vol.2013 (2013), p.1-3
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Biological response determinants in HSV-tk + ganciclovir gene therapy for prostate cancer
Author / Creator:Ayala, Gustavo ; Satoh, Takefumi ; Li, Rile ; Shalev, Moshe ; Gdor, Yehoshua ; Aguilar-Cordova, Estuardo ; Frolov, Anna ; Wheeler, Thomas M ; Miles, Brian J ; Rauen, Kate ; Teh, Bin S ; Butler, E Brian ; Thompson, Timothy C ; Kadmon, Dov
Publisher:United States: Elsevier Limited
Journal title:Molecular therapy, 2006-04, Vol.13 (4), p.716-728
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TAK, an HIV Tat-Associated Kinase, is a Member of the Cyclin-Dependent Family of Protein Kinases and is Induced by Activation of Peripheral Blood Lymphocytes and Differentiation of Promonocytic Cell L...
Author / Creator:Yang, Xinzhen ; Gold, Moses O. ; Tang, Derek Ng ; Lewis, Dorothy E. ; Aguilar-Cordova, Estuardo ; Rice, Andrew P. ; Herrmann, Christine H.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1997-11, Vol.94 (23), p.12331-12336
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Multiplicity of Infection/Multiplicity of Confusion
Author / Creator:Shabram, Paul ; Aguilar-Cordova, Estuardo
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2000-11, Vol.2 (5), p.420-421
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Impact of Preimmunization on Adenoviral Vector Expression and Toxicity in a Subcutaneous Mouse Cancer Model
Author / Creator:Vlachaki, Maria T. ; Hernandez-Garcia, Andres ; Ittmann, Michael ; Chhikara, Madhu ; Aguilar, Laura K. ; Zhu, Xiaohong ; The, Bin S. ; Butler, E.Brian ; Woo, Shiao ; Thompson, Timothy C. ; Barrera-Saldana, Hugo ; Aguilar-Cordova, Estuardo
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2002-09, Vol.6 (3), p.342-348
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Coxsackievirus-adenovirus receptor expression in ovarian cancer cell lines is associated with increased adenovirus transduction efficiency and transgene expression
Author / Creator:You, Z ; Fischer, D C ; Tong, X ; Hasenburg, A ; Aguilar-Cordova, E ; Kieback, D G
Publisher:England: Nature Publishing Group
Journal title:Cancer gene therapy, 2001-03, Vol.8 (3), p.168-175
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Clinical trial links oncolytic immunoactivation to survival in glioblastoma
Author / Creator:Ling, Alexander L. ; Solomon, Isaac H. ; Landivar, Ana Montalvo ; Nakashima, Hiroshi ; Woods, Jared K. ; Santos, Andres ; Masud, Nafisa ; Fell, Geoffrey ; Mo, Xiaokui ; Yilmaz, Ayse S. ; Grant, James ; Zhang, Abigail ; Bernstock, Joshua D. ; Torio, Erickson ; Ito, Hirotaka ; Liu, Junfeng ; Shono, Naoyuki ; Nowicki, Michal O. ; Triggs, Daniel ; Halloran, Patrick ; Piranlioglu, Raziye ; Soni, Himanshu ; Stopa, Brittany ; Bi, Wenya Linda ; Peruzzi, Pierpaolo ; Chen, Ethan ; Malinowski, Seth W. ; Prabhu, Michael C. ; Zeng, Yu ; Carlisle, Anne ; Rodig, Scott J. ; Wen, Patrick Y. ; Lee, Eudocia Quant ; Nayak, Lakshmi ; Chukwueke, Ugonma ; Gonzalez Castro, L. Nicolas ; Dumont, Sydney D. ; Batchelor, Tracy ; Kittelberger, Kara ; Tikhonova, Ekaterina ; Miheecheva, Natalia ; Tabakov, Dmitry ; Shin, Nara ; Gorbacheva, Alisa ; Shumskiy, Artemy ; Frenkel, Felix ; Aguilar-Cordova, Estuardo ; Aguilar, Laura K. ; Krisky, David ; Wechuck, James ; Manzanera, Andrea ; Matheny, Chris ; Tak, Paul P. ; Barone, Francesca ; Kovarsky, Daniel ; Tirosh, Itay ; Suvà, Mario L. ; Wucherpfennig, Kai W. ; Ligon, Keith ; Reardon, David A. ; Chiocca, E. Antonio
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-11, Vol.623 (7985), p.157-166
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Improved Effects of Viral Gene Delivery of Human uPA plus Biliodigestive Anastomosis Induce Recovery from Experimental Biliary Cirrhosis
Author / Creator:Miranda-Díaz, Alejandra ; Rincón, Ana Rosa ; Salgado, Silvia ; Vera-Cruz, José ; Gálvez, Javier ; Islas, Ma Cristina ; Berumen, Jaime ; Aguilar Cordova, Estuardo ; Armendáriz-Borunda, Juan
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2004-01, Vol.9 (1), p.30-37
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Thymidine kinase gene therapy with concomitant topotecan chemotherapy for recurrent ovarian cancer
Author / Creator:Hasenburg, A ; Tong, X W ; Rojas-Martinez, A ; Nyberg-Hoffman, C ; Kieback, C C ; Kaplan, A ; Kaufman, R H ; Ramzy, I ; Aguilar-Cordova, E ; Kieback, D G
Publisher:England: Nature Publishing Group
Journal title:Cancer gene therapy, 2000-06, Vol.7 (6), p.839-844
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The combination of adenoviral HSV TK gene therapy and radiation is effective in athymic mouse glioblastoma xenografts without increasing toxic side effects
Author / Creator:NESTLER, Ulf ; WAKIMOTO, Hiroaki ; SILLER-LOPEZ, Fernando ; AGUILAR, Laura K ; CHAKRAVARTI, Arnab ; MUZIKANSKY, Alona ; STEMMER-RACHAMIMOV, Anat ; CHIOCCA, E. Antonio ; AGUILAR-CORDOVA, Estuardo ; HOCHBERG, Fred H
Publisher:Dordrecht: Springer
Journal title:Journal of neuro-oncology, 2004-03, Vol.67 (1-2), p.177-188
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Metastatic and Nonmetastatic Models of Retinoblastoma
Author / Creator:Chévez-Barrios, Patricia ; Hurwitz, Mary Y. ; Louie, Kathryn ; Marcus, Karen T. ; Holcombe, Vien N. ; Schafer, Pamela ; Aguilar-Cordova, C. Estuardo ; Hurwitz, Richard L.
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 2000-10, Vol.157 (4), p.1405-1412
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Hepatocyte Gene Therapy in a Large Animal: A Neonatal Bovine Model of Citrullinemia
Author / Creator:Lee, Brendan ; Dennis, Julie A. ; Healy, Peter J. ; Mull, Benjamin ; Pastore, Lucio ; Yu, Hung ; Aguilar-Cordova, Estuardo ; O'Brien, William ; Reeds, Peter ; Beaudet, Arthur L.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (7), p.3981-3986
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Administration of Helper-Dependent Adenoviral Vectors and Sequential Delivery of Different Vector Serotype for Long-Term Liver-Directed Gene Transfer in Baboons
Author / Creator:Morral, Núria ; O'Neal, Wanda ; Rice, Karen ; Leland, Michele ; Kaplan, Johanne ; Piedra, Pedro A. ; Zhou, Heshan ; Parks, Robin J. ; Velji, Rizwan ; Aguilar-Córdova, Estuardo ; Wadsworth, Samuel ; Graham, Frank L. ; Kochanek, Stefan ; Carey, K. Dee ; Beaudet, Arthur L.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (22), p.12816-12821
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Intraperitoneal adenovirus-mediated suicide gene therapy in combination with either topotecan or paclitaxel in nude mice with human ovarian cancer
Author / Creator:Kieback, Dirk G ; Fischer, Dagmar-Christiane ; Engehausen, Dirk G ; Sauerbrei, Willi ; Oehler, Martin K ; Tong, Xiao-Wen ; Aguilar-Cordova, Estuardo
Publisher:New York: Nature Publishing Group US
Journal title:Cancer gene therapy, 2002-05, Vol.9 (5), p.478-481
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The Spectrum of Vaccine Therapies for Patients With Glioblastoma Multiforme
Author / Creator:Aguilar, Laura K. ; Arvizu, Mariel ; Aguilar-Cordova, Estuardo ; Chiocca, E. Antonio
Publisher:New York: Current Science Inc
Journal title:Current treatment options in oncology, 2012-12, Vol.13 (4), p.437-450
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Intraprostatic distribution and long-term follow-up after AdV-tk immunotherapy as neoadjuvant to surgery in patients with prostate cancer
Author / Creator:Rojas-Martínez, A ; Manzanera, A G ; Sukin, S W ; Esteban-María, J ; González-Guerrero, J F ; Gomez-Guerra, L ; Garza-Guajardo, R ; Flores-Gutiérrez, J P ; Elizondo Riojas, G ; Delgado-Enciso, I ; Ortiz-López, R ; Aguilar, L K ; Butler, E B ; Barrera-Saldaña, H A ; Aguilar-Cordova, E
Publisher:New York: Nature Publishing Group US
Journal title:Cancer gene therapy, 2013-11, Vol.20 (11), p.642-649
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Leveraging external data in the design and analysis of clinical trials in neuro-oncology

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Gene-mediated cytotoxic immunotherapy as adjuvant to surgery or chemoradiation for pancreatic adenocarcinoma

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468 Enhancers and repressors of immunotherapy: translational perspectives on gene-mediated cytotoxic immunotherapy in glioblastoma

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395 Detection of viral antigen and immune activation after intra-tumor injection of CAN-3110 (ICP-34.5 expressing HSV-1 oncolytic virus) in patients with recurrent high-grade glioma

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Therapeutic Endoscopic Ultrasonography : Intratumoral Injection for Pancreatic Adenocarcinoma

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Biological response determinants in HSV-tk + ganciclovir gene therapy for prostate cancer

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TAK, an HIV Tat-Associated Kinase, is a Member of the Cyclin-Dependent Family of Protein Kinases and is Induced by Activation of Peripheral Blood Lymphocytes and Differentiation of Promonocytic Cell L...

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Multiplicity of Infection/Multiplicity of Confusion

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Impact of Preimmunization on Adenoviral Vector Expression and Toxicity in a Subcutaneous Mouse Cancer Model

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Coxsackievirus-adenovirus receptor expression in ovarian cancer cell lines is associated with increased adenovirus transduction efficiency and transgene expression

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Clinical trial links oncolytic immunoactivation to survival in glioblastoma

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Improved Effects of Viral Gene Delivery of Human uPA plus Biliodigestive Anastomosis Induce Recovery from Experimental Biliary Cirrhosis

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Thymidine kinase gene therapy with concomitant topotecan chemotherapy for recurrent ovarian cancer

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The combination of adenoviral HSV TK gene therapy and radiation is effective in athymic mouse glioblastoma xenografts without increasing toxic side effects

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Metastatic and Nonmetastatic Models of Retinoblastoma

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Hepatocyte Gene Therapy in a Large Animal: A Neonatal Bovine Model of Citrullinemia

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Administration of Helper-Dependent Adenoviral Vectors and Sequential Delivery of Different Vector Serotype for Long-Term Liver-Directed Gene Transfer in Baboons

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Intraperitoneal adenovirus-mediated suicide gene therapy in combination with either topotecan or paclitaxel in nude mice with human ovarian cancer

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The Spectrum of Vaccine Therapies for Patients With Glioblastoma Multiforme

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Intraprostatic distribution and long-term follow-up after AdV-tk immunotherapy as neoadjuvant to surgery in patients with prostate cancer

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