Clinical trial links oncolytic immunoactivation to survival in glioblastoma
Clinical trial links oncolytic immunoactivation to survival in glioblastoma
About this item
Full title
Author / Creator
Ling, Alexander L. , Solomon, Isaac H. , Landivar, Ana Montalvo , Nakashima, Hiroshi , Woods, Jared K. , Santos, Andres , Masud, Nafisa , Fell, Geoffrey , Mo, Xiaokui , Yilmaz, Ayse S. , Grant, James , Zhang, Abigail , Bernstock, Joshua D. , Torio, Erickson , Ito, Hirotaka , Liu, Junfeng , Shono, Naoyuki , Nowicki, Michal O. , Triggs, Daniel , Halloran, Patrick , Piranlioglu, Raziye , Soni, Himanshu , Stopa, Brittany , Bi, Wenya Linda , Peruzzi, Pierpaolo , Chen, Ethan , Malinowski, Seth W. , Prabhu, Michael C. , Zeng, Yu , Carlisle, Anne , Rodig, Scott J. , Wen, Patrick Y. , Lee, Eudocia Quant , Nayak, Lakshmi , Chukwueke, Ugonma , Gonzalez Castro, L. Nicolas , Dumont, Sydney D. , Batchelor, Tracy , Kittelberger, Kara , Tikhonova, Ekaterina , Miheecheva, Natalia , Tabakov, Dmitry , Shin, Nara , Gorbacheva, Alisa , Shumskiy, Artemy , Frenkel, Felix , Aguilar-Cordova, Estuardo , Aguilar, Laura K. , Krisky, David , Wechuck, James , Manzanera, Andrea , Matheny, Chris , Tak, Paul P. , Barone, Francesca , Kovarsky, Daniel , Tirosh, Itay , Suvà, Mario L. , Wucherpfennig, Kai W. , Ligon, Keith , Reardon, David A. and Chiocca, E. Antonio
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Immunotherapy failures can result from the highly suppressive tumour microenvironment that characterizes aggressive forms of cancer such as recurrent glioblastoma (rGBM)
1
,
2
. Here we report the results of a first-in-human phase I trial in 41 patients with rGBM who were injected with CAN-3110—an oncolytic herpes virus (oHSV)
3
....
Alternative Titles
Full title
Clinical trial links oncolytic immunoactivation to survival in glioblastoma
Authors, Artists and Contributors
Author / Creator
Solomon, Isaac H.
Landivar, Ana Montalvo
Nakashima, Hiroshi
Woods, Jared K.
Santos, Andres
Masud, Nafisa
Fell, Geoffrey
Mo, Xiaokui
Yilmaz, Ayse S.
Grant, James
Zhang, Abigail
Bernstock, Joshua D.
Torio, Erickson
Ito, Hirotaka
Liu, Junfeng
Shono, Naoyuki
Nowicki, Michal O.
Triggs, Daniel
Halloran, Patrick
Piranlioglu, Raziye
Soni, Himanshu
Stopa, Brittany
Bi, Wenya Linda
Peruzzi, Pierpaolo
Chen, Ethan
Malinowski, Seth W.
Prabhu, Michael C.
Zeng, Yu
Carlisle, Anne
Rodig, Scott J.
Wen, Patrick Y.
Lee, Eudocia Quant
Nayak, Lakshmi
Chukwueke, Ugonma
Gonzalez Castro, L. Nicolas
Dumont, Sydney D.
Batchelor, Tracy
Kittelberger, Kara
Tikhonova, Ekaterina
Miheecheva, Natalia
Tabakov, Dmitry
Shin, Nara
Gorbacheva, Alisa
Shumskiy, Artemy
Frenkel, Felix
Aguilar-Cordova, Estuardo
Aguilar, Laura K.
Krisky, David
Wechuck, James
Manzanera, Andrea
Matheny, Chris
Tak, Paul P.
Barone, Francesca
Kovarsky, Daniel
Tirosh, Itay
Suvà, Mario L.
Wucherpfennig, Kai W.
Ligon, Keith
Reardon, David A.
Chiocca, E. Antonio
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10620094
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10620094
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06623-2
